Zobrazeno 1 - 6
of 6
pro vyhledávání: '"João N. Moreira"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Over the last decades, monoclonal antibodies have substantially improved the treatment of several conditions. The continuous search for novel therapeutic targets and improvements in antibody’s structure, demands for a constant optimization
Externí odkaz:
https://doaj.org/article/17c3af32150a45968f8b91c5e5f4f957
Autor:
Ângela Valério-Fernandes, Nuno A. Fonseca, Nélio Gonçalves, Ana F. Cruz, Marta I. Pereira, Ana C. Gregório, Vera Moura, Ana F. Ladeirinha, Ana Alarcão, Joana Gonçalves, Antero Abrunhosa, Joana B. Melo, Lina Carvalho, Sérgio Simões, João N. Moreira
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2217
Notwithstanding the advances in the treatment of lung cancer with immune checkpoint inhibitors, the high percentage of non-responders supports the development of novel anticancer treatments. Herein, the expression of the onco-target nucleolin in pati
Autor:
Pedro M Costa, Ana L Cardoso, Liliana S Mendonça, Angelo Serani, Carlos Custódia, Mariana Conceição, Sérgio Simões, João N Moreira, Luís Pereira de Almeida, Maria C Pedroso de Lima
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
The present work aimed at the development and application of a lipid-based nanocarrier for targeted delivery of nucleic acids to glioblastoma (GBM). For this purpose, chlorotoxin (CTX), a peptide reported to bind selectively to glioma cells while sho
Externí odkaz:
https://doaj.org/article/66ac7cd847d140d19c87aab6c7cc7aeb
Autor:
Nelson, Monteiro, Albino, Martins, Diana, Ribeiro, Susana, Faria, Nuno A, Fonseca, João N, Moreira, Rui L, Reis, Nuno M, Neves
Publikováno v:
Journal of tissue engineering and regenerative medicine. 9(9)
Stem cells have received considerable attention by the scientific community because of their potential for tissue engineering and regenerative medicine. The most frequently used method to promote their differentiation is supplementation of the in vit
Autor:
Chiara Brignole, Veronica Bensa, Nuno A. Fonseca, Genny Del Zotto, Silvia Bruno, Ana F. Cruz, Fabiana Malaguti, Barbara Carlini, Fabio Morandi, Enzo Calarco, Patrizia Perri, Vera Moura, Laura Emionite, Michele Cilli, Francesco De Leonardis, Annalisa Tondo, Loredana Amoroso, Massimo Conte, Alberto Garaventa, Angela R. Sementa, Maria V. Corrias, Mirco Ponzoni, Joao N. Moreira, Fabio Pastorino
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Abstract Background Neuroblastoma (NB) represents the most frequent and aggressive form of extracranial solid tumor of infants. Nucleolin (NCL) is a protein overexpressed and partially localized on the cell surface of tumor cells of adult cancers. Li
Externí odkaz:
https://doaj.org/article/74d59ac150f64c2ab3aaf5e3f878f108
Publikováno v:
Pharmaceutical research. 19(3)
Simple methods for the large-scale manufacture of ligand-targeted liposomes will be needed if clinical trials are to proceed. We tested a recently developed technology for inserting peptide ligands into preformed Stealth liposomes. Antagonist G-targe