Zobrazeno 1 - 10
of 295
pro vyhledávání: '"João Moreno"'
Autor:
Cristiana L. Pires, Maria João Moreno
Publikováno v:
Membranes, Vol 14, Iss 7, p 157 (2024)
The ability to predict the rate of permeation of new compounds across biological membranes is of high importance for their success as drugs, as it determines their efficacy, pharmacokinetics, and safety profile. In vitro permeability assays using Cac
Externí odkaz:
https://doaj.org/article/761a2770b15f49c68b85a6235b5239a8
Autor:
Coreta-Gomes, Filipe, Silva, Inês M.V., Nunes, Cláudia, Marin-Montesinos, Ildefonso, Evtuguin, Dmitry, Geraldes, Carlos F.G.C., João Moreno, Maria, Coimbra, Manuel A.
Publikováno v:
In Journal of Colloid And Interface Science 15 September 2023 646:775-783
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 620 (2024)
This Special Issue presents five contributions covering various topics, as it would be expected for an area as comprehensive and multidisciplinary as Macromolecules [...]
Externí odkaz:
https://doaj.org/article/6d6045a1e93444de806aa46584a66d5e
Autor:
Iris Correia, Madalena Antunes, Carla Tecelão, Marta Neves, Cristiana L. Pires, Pedro F. Cruz, Maria Rodrigues, Claúdia C. Peralta, Cidália D. Pereira, Fernando Reboredo, Maria João Moreno, Rui M. M. Brito, Vânia S. Ribeiro, Daniela C. Vaz, Maria Jorge Campos
Publikováno v:
Plants, Vol 13, Iss 3, p 427 (2024)
Crithmum maritimum L. (sea fennel), an edible xerophyte of coastal habitats, is considered an emerging cash crop for biosaline agriculture due to its salt-tolerance ability and potential applications in the agri-food sector. Here, the nutritional val
Externí odkaz:
https://doaj.org/article/fbd3204ff8504e4d9c0916ec3d4d8bd9
Publikováno v:
Membranes, Vol 13, Iss 6, p 551 (2023)
Permeation through biomembranes is ubiquitous for drugs to reach their active sites. Asymmetry of the cell plasma membrane (PM) has been described as having an important role in this process. Here we describe the interaction of a homologous series of
Externí odkaz:
https://doaj.org/article/a6f05a4d9cbc4413a275bdd632df30d8
Autor:
Diogo A. Pereira, Alexandre D. Silva, Patricia A. T. Martins, Ana P. Piedade, Dmitro Martynowych, David Veysset, Maria João Moreno, Carlos Serpa, Keith A. Nelson, Luis G. Arnaut
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Target delivery of large foreign materials to cells requires transient permeabilization of the cell membrane without toxicity. Giant unilamellar vesicles (GUVs) mimic the phospholipid bilayer of the cell membrane and are also useful drug del
Externí odkaz:
https://doaj.org/article/74c5f6fd006045a8b42db599ba9f2875
Autor:
Maria João Moreno, Armindo Salvador
Publikováno v:
Molecules, Vol 28, Iss 7, p 3136 (2023)
Ligand-protein interactions are usually studied in complex media that also contain lipids. This is particularly relevant for membrane proteins that are always associated with lipid bilayers, but also for water-soluble proteins studied in in vivo cond
Externí odkaz:
https://doaj.org/article/480d3902534a4f868f0f72591105b4ff
Autor:
Maria João Moreno, Hugo A. L. Filipe, Susana V. P. Cunha, Cristiana V. Ramos, Patrícia A. T. Martins, Biebele Abel, Luís M. S. Loura, Suresh V. Ambudkar
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 174 (2023)
The transport of drugs by efflux transporters in biomembranes limits their bioavailability and is a major determinant of drug resistance development by cancer cells and pathogens. A large number of chemically dissimilar drugs are transported, and des
Externí odkaz:
https://doaj.org/article/254c0ff6fc114e2ea036bbb3622ea762
Autor:
Ricardo C. deAbreu, Cristiana V. Ramos, Clarissa Becher, Miguel Lino, Carlos Jesus, Paula A. daCosta Martins, Patrícia A. T. Martins, Maria João Moreno, Hugo Fernandes, Lino Ferreira
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 10, Pp n/a-n/a (2021)
Abstract Small extracellular vesicles (sEVs), through their natural ability to interact with biological membranes and exploit endogenous processing pathways to convey biological information, are quintessential for the delivery of therapeutically rele
Externí odkaz:
https://doaj.org/article/4484de6cbf564657ba2c609e2c3bab5b
Autor:
Cristiana L. Pires, Inês M. V. Silva, Manuel A. Coimbra, Maria João Moreno, Filipe Coreta-Gomes
Publikováno v:
Foods, Vol 11, Iss 19, p 2935 (2022)
Absorption at the intestinal epithelium is a major determinant of cholesterol levels in the organism, influencing the entry of dietary cholesterol and the excretion of endogenous cholesterol. Several strategies are currently being followed to reduce
Externí odkaz:
https://doaj.org/article/9fe5d49e3a454c78a195aab13b1c53e3