Zobrazeno 1 - 8 of 8 pro vyhledávání: '"João M A Delou"'
1
Akademický článek
Saxitoxin potentiates human neuronal cell death induced by Zika virus while sparing neural progenitors and astrocytes
Autor: Leticia R. Q. Souza, Carolina G. da S. Pedrosa, Teresa Puig-Pijuan, Camila da Silva dos Santos, Gabriela Vitória, João M. A. Delou, Pedro Setti-Perdigão, Luiza M. Higa, Amilcar Tanuri, Stevens Kastrup Rehen, Marília Zaluar P. Guimarães
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The Zika virus (ZIKV) epidemic declared in Brazil between 2015 and 2016 was associated with an increased prevalence of severe congenital malformations, including microcephaly. The distribution of microcephaly cases was not uniform across the
Externí odkaz: https://doaj.org/article/d8dcaae1fcbd48feb4760630394c60cb
Zobrazit plný text záznamu
2
Akademický článek
Highlights in Resistance Mechanism Pathways for Combination Therapy
Autor: João M. A. Delou, Alana S. O. Souza, Leonel C. M. Souza, Helena L. Borges
Publikováno v: Cells, Vol 8, Iss 9, p 1013 (2019)
Combination chemotherapy has been a mainstay in cancer treatment for the last 60 years. Although the mechanisms of action and signaling pathways affected by most treatments with single antineoplastic agents might be relatively well understood, most c
Externí odkaz: https://doaj.org/article/6cfa520b675d41ff99a05cf469709d35
Zobrazit plný text záznamu
3
Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells
Autor: Rodrigo A. P. Martins, João M A Delou, Stevens K. Rehen, Renata de Moraes Maciel, Nathassya Accioly Lins Vidal Rodrigues, Helena L. Borges, Vera Lucia Antunes Chagas, Rossana C. Soletti, Deborah Biasoli
Publikováno v: Translational Oncology, Vol 10, Iss 5, Pp 726-733 (2017)
Translational Oncology
Esophageal cancer is the sixth most common cause of cancer-related death worldwide. Current chemotherapy regimens include a combination of 5-fluorouracil (5-FU) and cisplatin, but more efficient therapy strategies are needed to increase 5-year surviv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c383aaa85179b7ca4cd30e27011ecd15
http://www.sciencedirect.com/science/article/pii/S1936523317302024
Zobrazit plný text záznamu
4
The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB
Autor: Helena L. Borges, Deborah Biasoli, João M A Delou
Publikováno v: Anais da Academia Brasileira de Ciências, Vol 88, Iss 4, Pp 2257-2275
Anais da Academia Brasileira de Ciências, Volume: 88, Issue: 4, Pages: 2257-2275, Published: DEC 2016
Anais da Academia Brasileira de Ciências v.88 n.4 2016
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Physiological processes, as autophagy, proliferation and apoptosis are affected during carcinogenesis. Restoring cellular sensitivity to apoptotic stimuli, such as the antineoplastic cocktails, has been explored as a strategy to eliminate cancer cell
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02003f9201fccb0ac0c4c8df96ee213d
https://doi.org/10.1590/0001-3765201620160127
Zobrazit plný text záznamu
5
The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation
Autor: Alice H. Reis, Luiz F. S. Oliveira, Carlos A. M. Fraga, Laís S. S. Ferreira, Danilo Predes, Fabio A. Mendes, José G. Abreu, Helena L. Borges, Igor F. de Oliveira, Anderson Faletti, João M A Delou, Ricardo Machado Kuster, Nathalia G. Amado, Lorena A. Maia
Publikováno v: Cancers
Volume 11
Issue 12
The deregulation of the Wnt/&beta
catenin signaling pathway is a central event in colorectal cancer progression, thus a promising target for drug development. Many natural compounds, such as flavonoids, have been described as Wnt/&beta
cate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dde77e02d03618a9eb334910140ade4
https://pubmed.ncbi.nlm.nih.gov/31817828
Zobrazit plný text záznamu
7
The Role of KATP Channels on Propofol Preconditioning in a Cellular Model of Renal Ischemia-Reperfusion
Autor: Marcia A. M. Capella, Leonardo Marques da Fonseca, João M A Delou, Alexandra R. Assad, José Nascimento, Nivaldo R. Villela, Anibal Gil Lopes, Nubia Verçosa
Publikováno v: Anesthesia & Analgesia. 109:1486-1492
BACKGROUND: Propofol (2,6-diisopropylphenol) has been shown to protect several organs, including the kidneys, from ischemia-reperfusion (I-R)-induced injury. Although propofol affects adenosine triphosphate-sensitive potassium (KATP) channels in nonr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4cafcd513ce8b8151bdba9a40877a7
https://doi.org/10.1213/ane.0b013e3181b76396
Zobrazit plný text záznamu
8
Betulinic acid does not modulate the activity of P-gp/ABCB1 or MRP1/ABCC1 in a non-tumoral renal cell line: Possible utility in multidrug resistance cancer chemotherapy
Autor: Marcia A. M. Capella, Cerli Rocha Gattass, João M A Delou
Publikováno v: Molecular medicine reports. 2(2)
Multidrug resistance (MDR) is a multifactorial phenomenon considered to be the main cause of failure in cancer chemotherapy. One of the underlying mechanisms of MDR is the overexpression of membrane transporter proteins, such as P-glycoprotein (P-gp/
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0de78560c839bc5f87bee2f66d7609
https://pubmed.ncbi.nlm.nih.gov/21475824
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje