Zobrazeno 1 - 10 of 23 pro vyhledávání: '"João L, Baldim"'
1
Molecular dereplication of volatile oils from Saururus cernuus L. and evaluation of anti-Trypanosoma cruzi activity
Autor: João L. Baldim, Andre G. Tempone, Juliana Ferreira de Brito, Edgard A. Ferreira, Vinicius S. Londero, Thais A. Costa-Silva, João Henrique G. Lago
Publikováno v: Química Nova v.45 n.2 2022
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ
Química Nova, Volume: 45, Issue: 2, Pages: 159-164, Published: 22 APR 2022
The present study reports the molecular dereplication and the evaluation of anti-Trypanosoma cruzi activity of volatile oils from inflorescences, leaves, branches, and roots of Saururus cernuus L. (Saururaceae). Chemically, the oils showed the predom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b12ad8f815a69d199820be64041b50e
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000200159
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3
Akademický článek
The Genus Caesalpinia L. (Caesalpiniaceae): Phytochemical and Pharmacological Characteristics
Autor: João L. Baldim Zanin, Bianca A. de Carvalho, Paloma Salles Martineli, Marcelo Henrique dos Santos, João Henrique G. Lago, Patrícia Sartorelli, Cláudio Viegas, Marisi G. Soares
Publikováno v: Molecules, Vol 17, Iss 7, Pp 7887-7902 (2012)
The genus Caesalpinia (Caesalpiniaceae) has more than 500 species, many of which have not yet been investigated for potential pharmacological activity. Several classes of chemical compounds, such as flavonoids, diterpenes, and steroids, have been iso
Externí odkaz: https://doaj.org/article/b47ed2a57d64417593ddb6024d3aceea
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4
Akademický článek
Design and Synthesis of New Benzophenone Derivatives with In Vivo Anti-Inflammatory Activity through Dual Inhibition of Edema and Neutrophil Recruitment
Autor: Jaqueline P. Januario, Thiago B. de Souza, Stefânia N. Lavorato, Tatiane C. S. Maiolini, Olívia S. Domingos, João L. Baldim, Laís R. S. Folquitto, Marisi G. Soares, Daniela A. Chagas-Paula, Danielle F. Dias, Marcelo H. dos Santos
Publikováno v: Molecules, Vol 23, Iss 8, p 1859 (2018)
A series of novel benzophenone derivatives containing a thiazole heterocyclic nucleus were designed by molecular hybridization. Molecular docking studies have demonstrated the inhibitory potential of the designed compounds against cyclooxygenase (COX
Externí odkaz: https://doaj.org/article/226896cb152a4aaaa6e17cb7eef62ac7
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5
Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis
Autor: Diogo Oliveira-Silva, João Henrique G. Lago, Andrea M. Aguilar, Thais A. Costa-Silva, Wender A. Silva, Andre G. Tempone, João L. Baldim, Miriam Uemi, Kaio S. Gomes, Carlos Kleber Z. Andrade, Igor H. Oliveira, Lennine R. Melo
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 29:1459-1462
Chagas disease represents one of several neglected diseases with a reduced number of chemotherapeutical drugs including the highly toxic compounds benznidazole and nifurtimox. In this sense, natural products represent an import scaffold for the disco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1722e38246c7dd0eae37c5c3825ecac6
https://doi.org/10.1016/j.bmcl.2019.04.020
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7
The synergistic effects of volatile constituents of Ocimum basilicum against foodborne pathogens
Autor: Patrícia Lunardelli Negreiros de Carvalho, Daniela Aparecida Chagas-Paula, Jan Schripsema, Juliana Grell Fernandes Silveira, Anelique Pinto Almeida, Welton Rosa, Marisi G. Soares, João L. Baldim, Jaine H.H. Luiz
Publikováno v: Industrial Crops and Products. 112:821-829
Foodborne diseases and antibiotic resistant bacteria have become a serious worldwide public health problem. In this context, this study was carried out to describe the chemical composition and antimicrobial activity of the essential oils from three B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c074f84436a2b9489b47555bc18b2f1
https://doi.org/10.1016/j.indcrop.2017.12.016
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8
A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species
Autor: Daniela Aparecida Chagas-Paula, João L. Baldim, Bruna Lidiane da Silva, João Henrique G. Lago, Marisi G. Soares
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Nonribosomal peptides have an important pharmacological role due to their extensive biological properties. The singularities in the biosynthesis of these natural products allowed the development of genome-mining strategies which associate them to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d648ae3aa30ad97da494b699a652795
http://link.springer.com/article/10.1038/s41598-017-11314-w
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10
Anti-Inflammatory Derivatives with Dual Mechanism of Action from the Metabolomic Screening of Poincianella pluviosa
Autor: João Henrique G. Lago, Bianca Gonçalves Vasconcelos de Alcântara, Marisi G. Soares, Tatiane C. S. Maiolini, Daniela Aparecida Chagas-Paula, Olívia da Silva Domingos, João L. Baldim, Danielle Ferreira Dias, Mario F.C. Santos
Publikováno v: Molecules
Volume 24
Issue 23
Metabolomics approaches have become fundamental strategies for the analysis of complex mixtures, guiding the isolation of target compounds by focusing on unpublished or promising pharmacological properties. The discovery of novel anti-inflammatory ag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cb8ea955c27eb474188789e87b66e4
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