Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro

Autor: Lorena R. Sousa, Ana Gabriela S. Oliveira, Antônio Arantes, João Gabriel M. Junqueira, Gerso P. Alexandre, Vanessa G. P. Severino, Rui Manuel Reis, Bonglee Kim, Rosy I. M. A. Ribeiro

Publikováno v: Molecules, Vol 28, Iss 9, p 3809 (2023)

Glioblastoma (GBM) is an incurable primary brain tumor with a poor prognosis. Resection, radiation therapy, and temozolomide (TMZ) are insufficient to increase survival, making the treatment limited. Thus, the search for more effective and specific t

Externí odkaz: https://doaj.org/article/5c8721ccfe4f470297499e3b5dc16b14

In vivo and in vitro Volatile Constituents of the Flowers of Xylopia aromatica by HS‑SPME/GC-MS

Autor: João Gabriel M. Junqueira, Ana Paula Terezan, Mustapha N. Abubakar, Lincoln L. Romualdo, Lucas Gustavo da Costa, Vanessa Gisele Pasqualotto Severino, Francisco W. B. Aquino, Michelle N. G. do Nascimento, Gustavo O. S. Cunha

Publikováno v: Journal of the Brazilian Chemical Society.

Xylopia aromatica (Lam.) Mart. (Annonaceae) is a typical species from the Brazilian cerrado that presents medicinal properties. The plant is distinguished by its large white flowers which produce a pleasant fragrance. X. aromatica is characterized by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e82b1a19cbc55db5643f440e29424d54
https://doi.org/10.21577/0103-5053.20210013

Qualitative analysis of the acetogenins from Annona coriacea (Annonaceae) leaves by HPLC-Q-Orbitrap and their antibacterial potential against oral pathogens

Autor: Ana Paula Terezan, João Gabriel M. Junqueira, Mariana B. Santiago, Carlos Henrique Gomes Martins, Lucilia Kato, Cecília M. A. de Oliveira, Vanessa Gisele Pasqualotto Severino, Vinicius Galvao Wakui

Araticum is an edible and appreciable fruit of Annona coriacea, which is popularly known as a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of A. coriacea showed that HPLC-ESI-Q-Orbitrap® provided through PRM exper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843cb7f2225b7191f58c1f4abd16e4df

Annona coriacea Mart. Fractions Promote Cell Cycle Arrest and Inhibit Autophagic Flux in Human Cervical Cancer Cell Lines

Autor: Bruno G. Oliveira, Wanderson Romão, Renato José Silva-Oliveira, Rui Manuel Reis, Izabela Natalia Faria Gomes, Marcela N. Rosa, Maria Cristina Da Silva Barbosa, Fábio Vieira dos Santos, Viviane Aline Oliveira Silva, Patrik Da Silva Vital, João Gabriel M. Junqueira, Rosy Iara Maciel de Azambuja Ribeiro, Vanessa Gisele Pasqualotto Severino

Publikováno v: Molecules, Vol 24, Iss 21, p 3963 (2019)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
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Molecules
Volume 24
Issue 21

Plant-based compounds are an option to explore and perhaps overcome the limitations of current antitumor treatments. Annona coriacea Mart. is a plant with a broad spectrum of biological activities, but its antitumor activity is still unclear. The pur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1125a1eb7174e79b359730c9203fd7a9
https://www.mdpi.com/1420-3049/24/21/3963