Výsledky vyhledávání - "João Ferreira Martins"

Akademický článek

Potency evaluation of unfractionated heparins commercialized in Brazil through anti-factor Xa and anti-factor IIa chromogenic tests and coagulation assay

Autor: Renata Jurema Medeiros, Nathália Pessoa Gonçalves, Magno Maciel Magalhães, João Ferreira Martins, Tiago Savignon Cardoso Machado

Publikováno v: Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, Vol 11 (2023)

Introduction: Heparin is a drug that has anticoagulant activity, binding to antithrombin and accelerating the rate of inhibition of several proteases involved in the coagulation process. In the 2000s, the world market faced a troubled period regardin

Externí odkaz: https://doaj.org/article/53ba1a25eff74db089bc9fe41a155c13

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Akademický článek

p53 Modulates the Fate of Cardiac Progenitor Cells Ex Vivo and in the Diabetic Heart In Vivo

Autor: Ramaswamy Kannappan, Alex Matsuda, João Ferreira-Martins, Eric Zhang, Giorgia Palano, Anna Czarna, Mauricio Castro Cabral-Da-Silva, Adriana Bastos-Carvalho, Fumihiro Sanada, Noriko Ide, Marcello Rota, Maria A. Blasco, Manuel Serrano, Piero Anversa, Annarosa Leri

Publikováno v: EBioMedicine, Vol 16, Iss C, Pp 224-237 (2017)

p53 is an important modulator of stem cell fate, but its role in cardiac progenitor cells (CPCs) is unknown. Here, we tested the effects of a single extra-copy of p53 on the function of CPCs in the presence of oxidative stress mediated by doxorubicin

Externí odkaz: https://doaj.org/article/7447d72e79c84aae90e8708bafb7ff25

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Akademický článek

Revisiting the slow force response: The role of the PKG signaling pathway in the normal and the ischemic heart

Autor: Ricardo Castro-Ferreira, João Sérgio Neves, Ricardo Ladeiras-Lopes, André M. Leite-Moreira, Manuel Neiva-Sousa, João Almeida-Coelho, João Ferreira-Martins, Adelino F. Leite-Moreira

Publikováno v: Revista Portuguesa de Cardiologia, Vol 33, Iss 9, Pp 493-499 (2014)

Introduction: The myocardial response to acute stretch consists of a two-phase increase in contractility: an acute increase by the Frank-Starling mechanism and a gradual and time-dependent increase in force generated known as the slow force response

Externí odkaz: https://doaj.org/article/a19178a1916943dea0400504374b10b6

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Two-Step Distal Radial Artery Cannulation for Challenging Radial Anatomies

Autor: Pitt Lim, João Ferreira-Martins

Publikováno v: Cardiology. 146:144-150

The radial artery is the preferred access site for cardiac catheterization because of patient comfort, early ambulation, and improved survival in acute coronary syndromes, when compared to the femoral artery route. However, it is associated with a hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::766dfc169b38366a175646fe581e4397
https://doi.org/10.1159/000510293

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Akademický článek

O sistema apelinérgico: papel na fisiologia e patologia humanas e potenciais aplicações terapêuticas The apelinergic system: the role played in human physiology and pathology and potential therapeutic applications

Autor: Ricardo Ladeiras-Lopes, João Ferreira-Martins, Adelino F. Leite-Moreira

Publikováno v: Arquivos Brasileiros de Cardiologia, Vol 90, Iss 5, Pp 374-380 (2008)

A apelina é um peptídeo recentemente descoberto e identificado como o ligando endógeno do receptor APJ. A apelina e o receptor APJ são expressos numa grande variedade de tecidos, tais como coração, cérebro, rins e pulmões, onde a sua interaç

Externí odkaz: https://doaj.org/article/6b29a78181294701a7e919c2beeca9ff

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Outcomes of paroxysmal atrial fibrillation ablation studies are affected more by study design and patient mix than ablation technique

Autor: James P. Howard, Darrel P. Francis, Nicholas S. Peters, Laurence D. Sterns, Matthew J. Shun-Shin, Becker Al-khayatt, Afzal Sohaib, Rick Leather, Phang Boon Lim, Christopher Lane, Joseph Shalhoub, Markus B. Sikkel, Prapa Kanagaratnam, João Ferreira-Martins, Paul Novak

Publikováno v: Journal of Cardiovascular Electrophysiology. 29:1471-1479

OBJECTIVE We tested whether ablation methodology and study design can explain the varying outcomes in terms of atrial fibrillation (AF)-free survival at 1 year. BACKGROUND There have been numerous paroxysmal AF ablation trials, which are heterogeneou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed2b230211a6e82a07c1f6b2b3591a7
https://doi.org/10.1111/jce.13745

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Stretch-induced compliance: A novel adaptive biological mechanism following acute cardiac load

Autor: Ricardo Castro-Ferreira, Adelino F. Leite-Moreira, Ricardo Ladeiras-Lopes, Inês Falcão-Pires, A Leite-Moreira, Wolfgang A. Linke, Ana L. Pires, Daniela Miranda-Silva, Glória Conceição, João Ferreira-Martins, Patrícia Rodrigues, João Almeida-Coelho, André P. Lourenço, Melissa Herwig, Nazha Hamdani, João Sérgio Neves, Walter Paulus

Publikováno v: Leite-Moreira, A M, Almeida-Coelho, J, Neves, J S, Pires, A L, Ferreira-Martins, J, Castro-Ferreira, R, Ladeiras-Lopes, R, Conceição, G, Miranda-Silva, D, Rodrigues, P, Hamdani, N, Herwig, M, Falcão-Pires, I, Paulus, W J, Linke, W A, Lourenço, A P & Leite-Moreira, A F 2018, ' Stretch-induced compliance: A novel adaptive biological mechanism following acute cardiac load ', Cardiovascular Research, vol. 114, no. 5, pp. 656-667 . https://doi.org/10.1093/cvr/cvy026
Cardiovascular Research, 114(5), 656-667. Oxford University Press

Aims The heart is constantly challenged with acute bouts of stretching or overload. Systolic adaptations to these challenges are known but adaptations in diastolic stiffness remain unknown. We evaluated adaptations in myocardial stiffness due to acut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ff038f1412c4e16627e0667e58716a
https://doi.org/10.1093/cvr/cvy026

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