Zobrazeno 1 - 10
of 901
pro vyhledávání: '"João F. Mano"'
Autor:
Daping Xie, Congwei Han, Chonghao Chen, Zhencheng Liao, Senio Campos de Souza, Yiming Niu, João F. Mano, Lei Dong, Chunming Wang
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 315-330 (2024)
Cancer vaccination holds great promise for cancer treatment, but its effectiveness is hindered by suboptimal activation of CD8+ cytotoxic T lymphocytes, which are potent effectors to mediate anti-tumor immune responses. A possible solution is to swit
Externí odkaz:
https://doaj.org/article/63cce374d08d4b5183ab56a352bb148e
Autor:
Tiago Ferreira, I. Faustino-Rocha, Vítor M. Gaspar, Rui Medeiros, João F. Mano, Paula A. Oliveira
Publikováno v:
Veterinary World, Vol 17, Iss 5, Pp 1052-1072 (2024)
Chronic inflammation plays a crucial role in carcinogenesis. High levels of serum prostaglandin E2 and tissue overexpression of cyclooxygenase-2 (COX-2) have been described in breast, urinary, colorectal, prostate, and lung cancers as being involved
Externí odkaz:
https://doaj.org/article/bab2492cc924449997a39d3855e2714e
Publikováno v:
Small Science, Vol 4, Iss 5, Pp n/a-n/a (2024)
The encapsulation of single cells has emerged as a promising field in recent years, owing to its potential applications in cell‐based therapeutics, bioprinting, in vitro cell culture, high‐throughput screening, and diagnostics. Single‐cell unit
Externí odkaz:
https://doaj.org/article/325b9c212d304ee1b978fdf799a7fa51
Autor:
Tiago Ferreira, Maria Miranda, Rosário Pinto-Leite, João F. Mano, Rui Medeiros, Paula A. Oliveira, Adelina Gama
Publikováno v:
Veterinary Sciences, Vol 11, Iss 9, p 409 (2024)
Cancer is a complex pathological condition associated with substantial rates of mortality and morbidity in both humans and animals. Mammary gland tumors in intact female dogs are the most prevalent neoplasms. Surgical intervention remains the primary
Externí odkaz:
https://doaj.org/article/725c783eb9934f04b85c1b44789cce32
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Breakthroughs in precision cell surface engineering tools are supporting the rapid development of programmable living assemblies with valuable features for tackling complex biological problems. Herein, the authors overview the most recent te
Externí odkaz:
https://doaj.org/article/04de56358d0948b4a89ac586f96ac428
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100861- (2023)
Bone resident cells are constantly subjected to a range of distinct mechanical loadings, which generates a complex microenvironment. In particular, hydrostatic pressure (HP) has a key impact on modulation of cell function and fate determination. Alth
Externí odkaz:
https://doaj.org/article/2d432a7647d74a6a9093a76fb5691f31
Autor:
Maria P. Sousa, Catarina T. Passos, Marian Fürsatz, Haeshin Lee, Sónia G. Patrício, João F. Mano, Sylvia Nürnberger
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 8, Pp n/a-n/a (2023)
Articular cartilage injuries are currently one of the world's top health concerns owing to its limited capacity of self‐renewal, thus raising to the economic burden in the healthcare system. Cell implantation strategies resorting to a suitable deli
Externí odkaz:
https://doaj.org/article/79d8be358fde4f56bf24ac36dcd9754e
Autor:
Bárbara M. de Sousa, Clara R. Correia, Jorge A. F. Ferreira, João F. Mano, Edward P. Furlani, Marco P. Soares dos Santos, Sandra I. Vieira
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/0389cc6599444a89a210126898f0af33
Autor:
Vânia Camilo, Mariana Brütt Pacheco, Filipa Moreira-Silva, Gonçalo Outeiro-Pinho, Vítor M. Gaspar, João F. Mano, C. Joana Marques, Rui Henrique, Carmen Jerónimo
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1526 (2023)
The androgens/androgen receptor (AR) axis is the main therapeutic target in prostate cancer (PCa). However, while initially responsive, a subset of tumors loses AR expression through mechanisms putatively associated with epigenetic modifications. In
Externí odkaz:
https://doaj.org/article/c0e55395c7a34888b492be618a49ccf4
Autor:
Bárbara M. de Sousa, Clara R. Correia, Jorge A. F. Ferreira, João F. Mano, Edward P. Furlani, Marco P. Soares dos Santos, Sandra I. Vieira
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Replacement orthopedic surgeries are among the most common surgeries worldwide, but clinically used passive implants cannot prevent failure rates and inherent revision arthroplasties. Optimized non-instrumented implants, resorting to preclin
Externí odkaz:
https://doaj.org/article/281173fd7b014b119611c44e55c55dd1