Zobrazeno 1 - 10
of 28
pro vyhledávání: '"João Casaca"'
Autor:
Beatriz Alves, Pedro R. Mota, Daniela Sineiro, Ricardo Carmo, Pedro Santos, Patrícia Macedo, João Casaca Carreira, Rui Neves Madeira, Sofia Balula Dias, Carla Mendes Pereira
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionDespite the effectiveness of exercise-based interventions on symptom management and disease progression, many people with Parkinson’s Disease (PwPD) do not exercise regularly. In line with the ubiquitous use of digital health technology
Externí odkaz:
https://doaj.org/article/92659bf6a72b4cc5af5502b8429220b7
Autor:
Hugo Santos, Rita Brandão, Ana Partidário, Carolina Penha, Joana Almeida, Margarida Vieira, Patrícia Barrento, João Casaca
Publikováno v:
RevSALUS, Vol 6, Iss 2 (2024)
Introdução: Recentemente, a integração de meditação e técnicas de relaxamento, complementadas pelo biofeedback, tem ganhado atenção na psicologia clínica. Esta abordagem, não farmacológica e não invasiva, utiliza o biofeedback para permi
Externí odkaz:
https://doaj.org/article/ec4961eb778d4a369404d103c73cdf89
Autor:
Olena Brito, João Casaca Carreira
Publikováno v:
Annals of Medicine, Vol 53, Iss sup1, Pp S193-S193 (2021)
AbstractIntroduction In 2001 the World Health Organisation made the following statement: "the Mental Health – neglected for far too long – is crucial to the overall well-being of individuals, societies and countries" [1]. In Portugal, the focus o
Externí odkaz:
https://doaj.org/article/c3d7d77217ff4f278ec8367bdff9491b
Publikováno v:
Behavioural Neurology, Vol 2015 (2015)
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease caused by an expanded CAG repeat. The clinical features are progressive motor dysfunction, cognitive deterioration, and psychiatric disturbances. Unpredictable choreic mov
Externí odkaz:
https://doaj.org/article/7ecb723b8d824019bee0876a13b7a700
Akademický článek
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Autor:
João Casaca-Carreira, Ali Jahanshahi, Pilar Segura-Torres, Gemma Huguet, Yasin Temel, Sylvana Pol, Elisabet Kádár
Publikováno v:
Brain Research, 1712, 101-108. Elsevier
Hyperactivity of the dopaminergic pathway is thought to contribute to clinical symptoms in the early stages of Huntington's disease (HD). It is suggested to be result of a reduced dopaminergic inhibition by degeneration of medium spiny neurons in the
Autor:
Willeke M. C. van Roon-Mom, Hailiang Mei, João Casaca-Carreira, Ali Jahanshahi, Maria Pellisé-Tintoré, Lodewijk J.A. Toonen, Yasin Temel
Publikováno v:
Nucleic Acid Therapeutics
Nucleic Acid Therapeutics, 28(2), 63-73. Mary Ann Liebert Inc.
Nucleic Acid Therapeutics, 28(2), 63-73
Nucleic Acid Therapeutics, 28(2), 63-73. Mary Ann Liebert Inc.
Nucleic Acid Therapeutics, 28(2), 63-73
Antisense oligonucleotides (AONs) are versatile molecules that can be used to modulate gene expression by binding to RNA. The therapeutic potential of AONs appears particularly high in the central nervous system, due to excellent distribution and upt
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, 55(4), 2780-2788. Springer, Cham
Molecular Neurobiology, 55(4), 2780-2788. Springer, Cham
Drug delivery to the central nervous system (CNS) is complicated by the blood-brain barrier. As a result, many agents that are found to be potentially effective at their site of action cannot be sufficiently or effectively delivered to the CNS and th
Publikováno v:
The International Journal of Visual Design. 11:27-40
Akademický článek
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