Zobrazeno 1 - 10
of 14
pro vyhledávání: '"João C. F. Nunes"'
Autor:
Mafalda R. Almeida, Raquel O. Cristóvão, Maria A. Barros, João C. F. Nunes, Rui A. R. Boaventura, José M. Loureiro, Joaquim L. Faria, Márcia C. Neves, Mara G. Freire, Valéria C. Santos-Ebinuma, Ana P. M. Tavares, Cláudia G. Silva
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract l-asparaginase (ASNase, EC 3.5.1.1) is an enzyme that catalyzes the l-asparagine hydrolysis into l-aspartic acid and ammonia, being mainly applied in pharmaceutical and food industries. However, some disadvantages are associated with its fre
Externí odkaz:
https://doaj.org/article/3f5da1c099de4158876e8d4b70b363fa
Autor:
João C. F. Nunes, Raquel O. Cristóvão, Valéria C. Santos-Ebinuma, Joaquim L. Faria, Cláudia G. Silva, Márcia C. Neves, Mara G. Freire, Ana P. M. Tavares
Publikováno v:
Encyclopedia, Vol 1, Iss 3, Pp 848-858 (2021)
L-asparaginase (ASNase) is an aminohydrolase enzyme widely used in the pharmaceutical and food industries. Although currently its main applications are focused on the treatment of lymphoproliferative disorders such as acute lymphoblastic leukemia (AL
Externí odkaz:
https://doaj.org/article/980237c3f78f4394a984178fe4f02ea9
Autor:
João C. F. Nunes, Mafalda R. Almeida, Rui M. F. Bento, Matheus M. Pereira, Valéria C. Santos-Ebinuma, Márcia C. Neves, Mara G. Freire, Ana P. M. Tavares
Publikováno v:
Molecules, Vol 27, Iss 3, p 929 (2022)
L-asparaginase (ASNase) is an amidohydrolase that can be used as a biopharmaceutical, as an agent for acrylamide reduction, and as an active molecule for L-asparagine detection. However, its free form displays some limitations, such as the enzyme’s
Externí odkaz:
https://doaj.org/article/96c96805e6734bf992de3c0d169af574
Autor:
António Teixeira Rodrigues, João C. F. Nunes, Marta Estrela, Adolfo Figueiras, Fátima Roque, Maria Teresa Herdeiro
Publikováno v:
Antibiotics, Vol 10, Iss 6, p 629 (2021)
Background: Antibiotic resistance is a worldwide public health problem, leading to longer hospital stays, raising medical costs and mortality levels. As physicians’ attitudes are key factors to antibiotic prescribing, this study sought to explore t
Externí odkaz:
https://doaj.org/article/898186feb3ba4408bd6f207771b70da4
Autor:
João C. F. Nunes, Raquel O. Cristóvão, Mara G. Freire, Valéria C. Santos-Ebinuma, Joaquim L. Faria, Cláudia G. Silva, Ana P. M. Tavares
Publikováno v:
Molecules, Vol 25, Iss 24, p 5827 (2020)
l-asparaginase (ASNase, EC 3.5.1.1) is an aminohydrolase enzyme with important uses in the therapeutic/pharmaceutical and food industries. Its main applications are as an anticancer drug, mostly for acute lymphoblastic leukaemia (ALL) treatment, and
Externí odkaz:
https://doaj.org/article/52bb0101c1f44f29b3822e823ef74f8f
Autor:
Dibyendu Mondal, Mukesh Sharma, Ana P. M. Tavares, Nripat Singh, Mara G. Freire, Márcia C. Neves, João C. F. Nunes, Kamalesh Prasad
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Antibodies present in mammal's serum are of high relevance for therapeutic purposes, particularly in passive immunization and in the treatment of some chronic diseases. However, their widespread use is still compromised by the requirement of several
Autor:
Ana P. M. Tavares, José M. Loureiro, João C. F. Nunes, Rui A.R. Boaventura, Cláudia G. Silva, Mara G. Freire, Márcia C. Neves, Maria A. Barros, Mafalda R. Almeida, Joaquim L. Faria, Valéria C. Ebinuma-Santos, Raquel O. Cristóvão
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2020-12-12T01:38:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-08-24 The enzyme l-asparaginase (ASNase) presents effective antineoplastic properties used for acute lymphoblastic leukemia treatment besides their
Autor:
Maria Teresa Herdeiro, Adolfo Figueiras, Marta Estrela, João C. F. Nunes, António Teixeira Rodrigues, Fátima Roque
Publikováno v:
Antibiotics
Volume 10
Issue 6
Antibiotics, Vol 10, Iss 629, p 629 (2021)
CIÊNCIAVITAE
Volume 10
Issue 6
Antibiotics, Vol 10, Iss 629, p 629 (2021)
CIÊNCIAVITAE
Background: Antibiotic resistance is a worldwide public health problem, leading to longer hospital stays, raising medical costs and mortality levels. As physicians’ attitudes are key factors to antibiotic prescribing, this study sought to explore t
Autor:
Mara G. Freire, Márcia C. Neves, Mafalda R. Almeida, Ana P. M. Tavares, João C. F. Nunes, Cláudia G. Silva, Joaquim L. Faria
Proteins are one the most widely studied biomolecules with diverse functions and applications. Aiming at overcoming the current drawbacks of purification processes of proteins, the introduction of ionic liquids (ILs) has been a hot topic of research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40d9e8d5aa21ea397c9d41f171e3215
http://hdl.handle.net/10773/32798
http://hdl.handle.net/10773/32798
Autor:
Flávia F. Magalhães, Mafalda R. Almeida, Ana P. M. Tavares, João C. F. Nunes, Mara G. Freire, Ana M. Ferreira, Marília T. Araújo
Publikováno v:
Environmental and Microbial Biotechnology ISBN: 9789811566066
Microbial biosurfactants are amphiphilic compounds and surface-active biomolecules produced by several microorganisms. Recently, biosurfactants have emerged as promising agents for cancer therapy since a high diversity of these molecules has shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb99f084bb3fdee68b896eca655ba5b
https://doi.org/10.1007/978-981-15-6607-3_8
https://doi.org/10.1007/978-981-15-6607-3_8