Decellularized dermal matrices: unleashing the potential in tissue engineering and regenerative medicine

Autor: Marta Rosadas, Inês V. Silva, João B. Costa, Viviana P. Ribeiro, Ana L. Oliveira

Publikováno v: Frontiers in Materials, Vol 10 (2024)

Decellularized dermal matrices (dDMs) have emerged as effective biomaterials that can revolutionize regenerative medicine, particularly in the field of wound healing and tissue regeneration. Derived from animal or human skin, dDMs offer great biocomp

Externí odkaz: https://doaj.org/article/f3ba4078fd824d86a07f7060a0e98c06

Bioinspired Silk Fibroin-Based Composite Grafts as Bone Tunnel Fillers for Anterior Cruciate Ligament Reconstruction

Autor: Viviana P. Ribeiro, João B. Costa, Sofia M. Carneiro, Sandra Pina, Ana C. A. Veloso, Rui L. Reis, Joaquim M. Oliveira

Publikováno v: Pharmaceutics, Vol 14, Iss 4, p 697 (2022)

Anterior cruciate ligament (ACL) replacement is still a big challenge in orthopedics due to the need to develop bioinspired implants that can mimic the complexity of bone-ligament interface. In this study, we propose biomimetic composite tubular graf

Externí odkaz: https://doaj.org/article/237fff9d93524534867af436732381ca

Synergistic Effect of Co-Culturing Breast Cancer Cells and Fibroblasts in the Formation of Tumoroid Clusters and Design of In Vitro 3D Models for the Testing of Anticancer Agents

Autor: Lara Pierantoni, Virginia Brancato, João B. Costa, Subhas C. Kundu, Rui L. Reis, Joana Silva‐Correia, Joaquim M. Oliveira

Breast cancer is still the leading cause of women's death due to relapse and metastasis. In vitro tumor models are considered reliable tools for drug screening and understanding cancer-driving mechanisms due to the possibility of mimicking tumor hete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee0f1c5bac36cdb6817b5a263478ffa
https://hdl.handle.net/10281/404598

Enhanced performance of chitosan/keratin membranes with potential application in peripheral nerve repair

Autor: Cristiana R. Carvalho, Joaquim M. Oliveira, Zi Kuang Moay, João B. Costa, Rui L. Reis, Joana Silva-Correia, Lígia Costa, Kee Woei Ng

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Although surgical management of peripheral nerve injuries (PNIs) has improved over time, autographs are still the current â gold standardâ treatment for PNIs, which presents numerous limitations. In an attempt to improve natural biomaterial-based n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5c5d75d93bfa7840d5de8767a1dfdf
https://doi.org/10.1039/c9bm01098j

Convection patterns gradients of non-living and living micro-entities in hydrogels

Autor: Raphaël F. Canadas, Hélder Pereira, Pedro Patrício, Ping Yong, Virginia Brancato, Ricardo A. Pires, Joaquim M. Oliveira, João B. Costa, David Caballero, Jie Chen, Lucília P. da Silva, Alexandra P. Marques, Luca Gasperini, Subhas C. Kundu, Rui L. Reis, Nuno A. M. Araújo

Publikováno v: Applied Materials Today
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

"Available online 28 October 2020"
Inducing thermal gradients in two injected fluid systems results in the temporal formation of mixing conductive streams. If preserved through sol-gel transition, this mechanism can be used to drive and pattern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264b8e83ee1faa2f0ac372198bc131bc