Zobrazeno 1 - 10
of 48
pro vyhledávání: '"João Alfredo Moraes"'
Autor:
PALLOMA P. ALMEIDA, JOÃO ALFREDO MORAES, THEREZA CHRISTINA BARJA-FIDALGO, MARIANA RENOVATO-MARTINS
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 96, Iss 2 (2024)
Abstract The tumor microenvironment (TME) harbors several cell types, such as tumor cells, immune cells, and non-immune cells. These cells communicate through several mechanisms, such as cell-cell contact, cytokines, chemokines, and extracellular ves
Externí odkaz:
https://doaj.org/article/37c9336e67e544dfb513d1728bd1f7eb
Autor:
Mariana Paranhos Stelling, Mariana Alves Soares, Simone Coutinho Cardoso, Juliana Maria Motta, Joice Côrtes de Abreu, Maria Júlia Mansur Antunes, Vitória Gonçalves de Freitas, João Alfredo Moraes, Morgana Teixeira Lima Castelo-Branco, Carlos Alberto Pérez, Mauro Sérgio Gonçalves Pavão
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Metastatic disease remains the leading cause of death in cancer and understanding the mechanisms involved in tumor progression continues to be challenging. This work investigates the role of manganese in tumor progression in an in vivo model
Externí odkaz:
https://doaj.org/article/370f2dfe185d4939bf84bb7c3bcef871
Autor:
Carolinne Souza Amorim, João Alfredo Moraes, Ingrid de Jesus Magdalena, Sheila Gutiérrez López, Ana Carolina Dudenhoeffer Carneiro, Isabelle Karine da Costa Nunes, Luciana Pizzatti, Vinícius Figueiredo Sardela, Francisco Radler Aquino Neto, Luciana Cristina Mirotti, Henrique Marcelo Gualberto Pereira, Mariana Renovato-Martins
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/c3b7e3f1443b4626aacaa6a9049b289c
Autor:
Carolinne Amorim, Clara Luisa Docasar, Daniel Guimarães-Bastos, Ana Clara Frony, Christina Barja-Fidalgo, Mariana Renovato-Martins, João Alfredo Moraes
Publikováno v:
Cells, Vol 11, Iss 12, p 1875 (2022)
Immune system cells, including neutrophils, are recruited by the tumor microenvironment as a site of chronic inflammation and begin to favor tumor growth. Neutrophils present in the tumor site are called tumor-associated neutrophils (TAN) and can pre
Externí odkaz:
https://doaj.org/article/e47bb360e1a44b619eaea18c662c964d
Autor:
João Alfredo Moraes, Genilson Rodrigues, Daniel Guimarães-Bastos, Vany Nascimento-Silva, Erik Svensjö, Mariana Renovato-Martins, Markus Berger, Jorge Guimarães, Christina Barja-Fidalgo
Publikováno v:
Toxins, Vol 13, Iss 12, p 908 (2021)
The significant incidence of deforestation in South America culminates in the contact of humans with typical forests species. Among these species, one may highlight Lonomia obliqua caterpillar, which, when touched by humans, can poison them through t
Externí odkaz:
https://doaj.org/article/ee1fb883df1c4f58acf09e6f805c7730
Autor:
Isabella Cattani-Cavalieri, Helber da Maia Valença, João Alfredo Moraes, Lycia Brito-Gitirana, Bruna Romana-Souza, Martina Schmidt, Samuel Santos Valença
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9658 (2020)
Air pollution is mainly caused by burning of fossil fuels, such as diesel, and is associated with increased morbidity and mortality due to adverse health effects induced by inflammation and oxidative stress. Dimethyl fumarate (DMF) is a fumaric acid
Externí odkaz:
https://doaj.org/article/5789a1383d014e148ae1bc7106a1c248
Autor:
João Alfredo Moraes, Ana Clara Frony, Aline Maria Dias, Mariana Renovato-Martins, Genilson Rodrigues, Cezary Marcinkiewicz, Jamil Assreuy, Christina Barja-Fidalgo
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 330-340 (2016)
The data provides information in support of the research article Moraes et al., Atherosclerosis 243(2) (2015) 477–485 [1]. Here we provide data behind the mechanisms involved in Angiotensin II (Ang II) effects on vascular smooth muscle cells (VSMC)
Externí odkaz:
https://doaj.org/article/203ae3c8f7df4f8a852327a860a9e046
Autor:
Jessica Silva Santos de Oliveira, Gabriela da Silva Santos, João Alfredo Moraes, Alessandra Mattos Saliba, Thereza Christina Barja-Fidalgo, Ana Luíza Mattos-Guaraldi, Prescilla Emy Nagao
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 113, Iss 6 (2018)
BACKGROUND Streptococcus agalactiae can causes sepsis, pneumonia, and meningitis in neonates, the elderly, and immunocompromised patients. Although the virulence properties of S. agalactiae have been partially elucidated, the molecular mechanisms rel
Externí odkaz:
https://doaj.org/article/ae9b44a5089b4acdb683229fa8e9809d
Autor:
João Alfredo Moraes, Genilson Rodrigues, Vany Nascimento-Silva, Mariana Renovato-Martins, Markus Berger, Jorge Almeida Guimarães, Christina Barja-Fidalgo
Publikováno v:
Toxins, Vol 9, Iss 11, p 360 (2017)
Envenomation caused by human contact with the caterpillar Lonomia is characterized by deleterious effects on coagulation and patency of blood vessels. The cellular effects induced by Lonomia obliqua venom highlights its capacity to activate endotheli
Externí odkaz:
https://doaj.org/article/cbbaf052a9d24d0f87693e63cd7d66e4
Autor:
Cristiane Ribeiro-Pereira, João Alfredo Moraes, Mariele de Jesus Souza, Francisco R Laurindo, Maria Augusta Arruda, Christina Barja-Fidalgo
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99481 (2014)
Studies have demonstrated that reactive oxygen species (ROS) generated by NADPH oxidase are essential for melanoma proliferation and survival. However, the mechanisms by which NADPH oxidase regulates these effects are still unclear. In this work, we
Externí odkaz:
https://doaj.org/article/772f779025b44661bfb762983d9ef443