Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

Autor: Noguchi, Tetsuro, Caldes, Trinidad, Caligo, Maria, Viel, Alessandra, Ramus, Susan J., Claes, Kathleen, Aalfs, Cora M., Kaufman, Bella, Friedman, Eitan, Manoukian, Siranoush, Jernström, Helena, Milgrom, Roni, Schönbuchner, Ines, Cole, Trevor, Allavena, Anna, Isaacs, Claudine, Lazaro, Conxi, Chen, Xiaoqing, Buys, Saundra S., Porteous, Mary E., Hansen, Thomas V.O., Wang, Xianshu, Hardouin, Agnès, Arnold, Norbert, Benitez, Javier, Engel, Christoph, Simard, Jacques, Cook, Jackie, Jensen, Uffe Birk, Preisler-Adams, Sabine, Rantala, Johanna, Walker, Lisa, Meindl, Alfons, Montagna, Marco, Beesley, Jonathan, Aittomäki, Kristiina, Terry, Mary B., Vénat-Bouvet, Laurence, Faivre, Laurence, Miron, Alexander, Domchek, Susan, McGuffog, Lesley, Zikan, Michal, Godino, Javier, Neuhausen, Susan L., Lindblom, Annika, Nathanson, Kate, Van Der Luijt, Rob B., Meijers-Heijboer, E. J., Hamann, Ute, Mazoyer, Sylvie, Davidson, Rosemarie, Hogervorst, Frans, Spurdle, Amanda B., Lalloo, Fiona, Rennert, Gad, Niederacher, Dieter, Zaffaroni, Daniela, Blanco, Ignacio, Wappenschmidt, Barbara, Szabo, Csilla I., Gadzicki, Dorothea, Dubrovsky, Maya, Peock, Susan, Dutra-Clarke, Ana, Ganz, Patricia A., Peterlongo, Paolo, Weitzel, Jeffrey N., Poppe, Bruce, Rodriguez, Gustavo C., Lasset, Christine, Bonadona, Valérie, Mai, Phuong L., Dorkins, Huw, Lubinski, Jan, Glendon, Gord, Holland, Helene, Frénay, Marc, Rebbeck, Timothy R., Hopper, John L., Blok, Marinus J., Offit, Kenneth, Borg, Ake, Lejbkowicz, Flavio, Devilee, Peter, Frost, Debra, Blank, Stephanie V., Kirchhoff, Tomas, Van Asperen, Christi J., Agnarsson, Bjarni A., Foretova, Lenka, Deissler, Helmut, Lindor, Noralane M., Nevanlinna, Heli, Kriege, Mieke, Toland, Amanda Ewart, Gschwantler-Kaulich, Daphne, Rouleau, Etienne, De Pauw, Antoine, Karlan, Beth Y., Goldgar, David, Oliver, Clare, Godwin, Andrew K., Olopade, Olufunmilayo I., Osorio, Ana, Easton, Douglas F., Cohen, Shimrit, Berthet, Pascaline, Tihomirova, Laima, Platte, Radka, Lasa, Adriana, Rookus, Matti, Conroy, Don, Couch, Fergus J., Loustalot, Catherine, Sobol, Hagay, Chenevix-Trench, Georgia, Piedmonte, Marion, Schwartz, Peter E., Imyanitov, Evgeny, Heidemann, Simone, Barile, Monica, Casella, Cinzia, Jnson, Lars, Laitman, Yael, Healey, Sue, Schmutzler, Rita, Cruger, Dorthe, Sunde, Lone, Ding, Yuan Chun, Nogues, Catherine, Dall'Olio, Valentina, Yassin, Yosuf, Antoniou, Antonis C., Leroux, Dominique, Sutter, Christian, Evans, D. Gareth, Huzarski, Tomasz, Daly, Mary B., Pichert, Gabriella, Lochmann, Magdalena, Kast, Karin, Gross, Jenny, Stoppa-Lyonnet, Dominique, Andrulis, Irene L., Melin, Beatrice, Dreyfus, Hélène, Stenmark-Askmalm, Marie, Gerdes, Anne Marie, Boggess, John F., Paterson, Joan, Kennedy, M. John, Thomassen, Mads, Pfeiler, Georg, Basil, Jack, Devlin, Vincent, Tejada, Maria Isabel, Hoogerbrugge, Nicoline, Cook, Margaret, De La Hoya, Miguel, Pankratz, Vernon S., Sucheston, Lara, Radice, Paolo, John, Esther M., Singer, Christian F., Peissel, Bernard, Lynch, Henry T., Varon-Mateeva, Raymonda, Hodgson, Shirley, Durán, Mercedes, Greene, Mark H., Wakeley, Katie, Sinilnikova, Olga M., Dressler, Anne Catharina, Ozcelik, Hilmi, Morrison, Patrick J., Jakubowska, Ania, Tomlinson, Gail

The known breast cancer (BC) susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1,LSP1 and 2q35 confer increased risks of BC for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of three additional SNPs, rs4973768 in SLC4A7/NEK10,

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