Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jnanankur Bag"'
Autor:
Andrea-Kaye Datu, Jnanankur Bag
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64171 (2013)
UNLABELLED: The mRNAs encoding poly (A) binding protein (PABP1), eukaryotic elongation factor 1A (eEF1A) and ribosomal protein S6 (RPS6) belong to the family of terminal oligo pyrimidine tract (TOP) containing mRNAs. Translation of the TOP mRNAs is r
Externí odkaz:
https://doaj.org/article/2aebde6193ba4188a630a2c5df678f51
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e53036 (2012)
BACKGROUND: In vertebrates, poly(A) binding protein (PABP) is known to exist in five different isoforms. PABPs are primarily cytosolic with the exception of the nuclear PABP (PABPN1), which is located in the nucleus. Within the nucleus, PABPN1 is bel
Externí odkaz:
https://doaj.org/article/d68d5834ee0a436fbd7d2644f1368d80
Publikováno v:
RNA Biology. 7:5-12
Regulating gene expression at the post transcriptional level allows cells to respond quickly to external conditions without remodeling the genome. This approach is advantageous for responding to growth conditions and various cellular stresses. Contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e35060b8aae6c7db3fdb2d1a5f41c54
https://doi.org/10.4161/rna.7.1.10256
https://doi.org/10.4161/rna.7.1.10256
Publikováno v:
FEBS Journal. 276:552-570
Induction of heat shock proteins (HSPs) helps cells to survive severe hyperthermal stress and removes toxic unfolded proteins. At the same time, the cap-dependent translation of global cellular mRNA is inhibited, due to the loss of function of eukary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b351b1b2243f8892e396a47110a2f015
https://doi.org/10.1111/j.1742-4658.2008.06803.x
https://doi.org/10.1111/j.1742-4658.2008.06803.x
Autor:
Qishan Wang, Jnanankur Bag
Publikováno v:
Biochemical and Biophysical Research Communications. 370:11-15
Formation of nuclear inclusions consisting of aggregates of a polyalanine expansion mutant of nuclear poly(A)-binding protein (PABPN1) is the hallmark of oculopharyngeal muscular dystrophy (OPMD). OPMD is a late onset autosomal dominant disease. Pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc6e0025c1a37c630ea76d0eb21e833
https://doi.org/10.1016/j.bbrc.2008.02.162
https://doi.org/10.1016/j.bbrc.2008.02.162
Publikováno v:
RNA biology. 12(3)
The rate of secretion of αs2-casein into bovine milk is approximately 25% of that of β-casein, yet mammary expression of their respective mRNA transcripts (csn1s2 and csn2) is not different. Our objective was to identify molecular mechanisms that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d9c3840a42a1765b808a53bbd0fa55
https://pubmed.ncbi.nlm.nih.gov/25826667
https://pubmed.ncbi.nlm.nih.gov/25826667
The rate of secretion of αs2-casein into bovine milk is approximately 25% of that of β-casein, yet mammary expression of their respective mRNA transcripts (csn1s2 and csn2) is not different. Our objective was to identify molecular mechanisms that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee1c18848225a643e42b7507e090753
Autor:
Jnanankur Bag, Gopal P. Patel
Publikováno v:
FEBS Journal. 273:5678-5690
Repression of poly(A)-binding protein (PABP) mRNA translation involves the formation of a heterotrimeric ribonucleoprotein complex by the binding of PABP, insulin-like growth factor II mRNA binding protein-1 (IMP1) and the unr gene encoded polypeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a91109e3118eef8eb2d5fbf28262da59
https://doi.org/10.1111/j.1742-4658.2006.05556.x
https://doi.org/10.1111/j.1742-4658.2006.05556.x
Publikováno v:
Nucleic Acids Research
Repression of poly(A)-binding protein (PABP) mRNA translation involves the binding of PABP to the adenine-rich autoregulatory sequence (ARS) in the 5'-untranslated region of its own mRNA. In this report, we show that the ARS forms a complex in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db03e2854b931b32b2ee75782bef1d1c
http://europepmc.org/articles/PMC1316114
http://europepmc.org/articles/PMC1316114
Autor:
Jnanankur Bag
Publikováno v:
Journal of Biological Chemistry. 276:47352-47360
An adenine-rich cis element at the 5′-untranslated region (UTR) of Pabp1 mRNA is able to inhibit translation of its own mRNA. Similar inhibition of translation of a reporter β-galactosidase mRNA is observed when the adenine-rich auto regulatory se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d68541c231cae06f8f9c85bd29aff367
https://doi.org/10.1074/jbc.m107676200
https://doi.org/10.1074/jbc.m107676200