Effects of alatriopril, a mixed inhibitor of atriopeptidase and angiotensin I-converting enzyme, on cardiac hypertrophy and hormonal responses in rats with myocardial infarction. Comparison with captopril

Autor: Bralet J, christine marie, Mossiat C, Jm, Lecomte, Gros C, Jc, Schwartz

Publikováno v: Europe PubMed Central

The aim of the study was to compare, in a rat model of congestive heart failure, the effect of captopril, a selective angiotensin-converting enzyme (ACE; EC 3.4.15.1) inhibitor, to that of alatriopril, a mixed inhibitor of ACE and atriopeptidase (EC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6a59221af5215eafdbc168fbdf28175e
https://pubmed.ncbi.nlm.nih.gov/8035346

Pitolisant 40 mg for excessive daytime sleepiness in obstructive sleep apnea patients treated or not by CPAP: Randomised phase 3 study.

Autor: Dauvilliers Y; Centre National de Référence Narcolepsie, Unité du Sommeil, CHU Montpellier, Hôpital Gui-de-Chauliac, Service de Neurologie, Université de Montpellier, INSERM INM, Montpellier, France., Craig SE; Liverpool Sleep and Ventilation Centre, University Hospital Aintree, Liverpool University Foundation Trust, Liverpool, UK., Bonsignore MR; PROMISE Department, University of Palermo, Institute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), Palermo, Italy., Barbé F; Respiratory Department, Institut Ricerca Biomedica de Vilanova, Lleida, Spain., Verbraecken J; Multidisciplinary Sleep Disorders Centre, Antwerp University Hospital and University of Antwerp, Edegem-Antwerp, Belgium., Asin J; Department of Pulmonary Medicine, Centre for Sleep Medicine, Amphia Hospital, Breda, The Netherlands., Georgiev O; Department of Internal Medicine, Pulmonology, Alexandrovska Hospital Medical University, Sofia, Bulgaria., Tiholov R; Department of Internal Diseases, Sv. Ivan Rilski Multiprofile Hospital for Active Treatment, Kozloduy, Bulgaria., Caussé C; Bioprojet Pharma, Paris, France., Lecomte JM; Bioprojet Pharma, Paris, France., Schwartz JC; Bioprojet Pharma, Paris, France., Lehert P; Faculty of Economics, University Louvain, Ottignies-Louvain-la-Neuve, Belgium.; Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia., Randerath W; Bethanien Hospital, Institute of Pneumonology, University of Cologne, Solingen, Germany., Pépin JL; HP2 Laboratory INSERM U1300, University Grenoble Alpes, Grenoble, France.

Publikováno v: Journal of sleep research [J Sleep Res] 2024 Oct 08, pp. e14373. Date of Electronic Publication: 2024 Oct 08.

Safety and efficacy of pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy: a double-blind, randomised, placebo-controlled trial.

Autor: Dauvilliers Y; Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, University of Montpellier, INSERM INM, Montpellier, France. Electronic address: ydauvilliers@yahoo.fr., Lecendreux M; AP-HP, Pediatric Sleep Center, Hospital Robert-Debre, National Reference Centre for Orphan Diseases, Narcolepsy, Idiopathic Hypersomnia, and Kleine-Levin Syndrome, INSERM CIC1426, Paris, France., Lammers GJ; Neurologist-Somnologist, Sleep-Wake Center Stichting Epilepsie Centra Nederland, Heemstede, Netherlands; Department of Neurology Leiden University Medical Center, Leiden, the Netherlands Department, Heemstede, Netherlands., Franco P; Hôpital Femme-Mère-Enfant, Unité de Sommeil Pédiatrique and Centre National de Référence Narcolepsie, INSERM U628, Lyon, France., Poluektov M; I M Sechenov First Moscow State Medical University, Moscow, Russia., Caussé C; Bioprojet, Paris, France., Lecomte I; Bioprojet, Paris, France., Lecomte JM; Bioprojet, Paris, France., Lehert P; Louvain School of Management, Louvain University, Belgium; Faculty of Medicine, University of Melbourne, Parkville, VIC, Australia., Schwartz JC; Bioprojet, Paris, France., Plazzi G; IRCCS Istituto delle Scienze Neurologiche, Bologna, Italy; Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy. Electronic address: giuseppe.plazzi@isnb.it.

Publikováno v: The Lancet. Neurology [Lancet Neurol] 2023 Apr; Vol. 22 (4), pp. 303-311.

Pitolisant, a wake-promoting agent devoid of psychostimulant properties: Preclinical comparison with amphetamine, modafinil, and solriamfetol.

Autor: Krief S; Bioprojet-Biotech, Saint-Grégoire, France., Berrebi-Bertrand I; Bioprojet-Biotech, Saint-Grégoire, France., Nagmar I; Bioprojet-Biotech, Saint-Grégoire, France., Giret M; Bioprojet-Biotech, Saint-Grégoire, France., Belliard S; Bioprojet-Biotech, Saint-Grégoire, France., Perrin D; Bioprojet-Biotech, Saint-Grégoire, France., Uguen M; Bioprojet-Biotech, Saint-Grégoire, France., Robert P; Bioprojet-Biotech, Saint-Grégoire, France., Lecomte JM; Bioprojet-Biotech, Saint-Grégoire, France., Schwartz JC; Bioprojet-Biotech, Saint-Grégoire, France., Finance O; Bioprojet-Biotech, Saint-Grégoire, France., Ligneau X; Bioprojet-Biotech, Saint-Grégoire, France.

Publikováno v: Pharmacology research & perspectives [Pharmacol Res Perspect] 2021 Oct; Vol. 9 (5), pp. e00855.

Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial.

Autor: Dauvilliers Y; National Reference Center for Narcolepsy, Sleep and Wake Unit, Department of Neurology, Gui-de-Chauliac Hospital, Montpellier University Hospital, Montpellier, France.; INSERM U1061, Montpellier University, Montpellier, France., Verbraecken J; Multidisciplinary Sleep Disorders Center, Antwerp University Hospital and University of Antwerp, Antwerp, Belgium.; University of Antwerp, Antwerp, Belgium., Partinen M; Helsinki Sleep Clinic, Vitalmed Research Center, Helsinki, Finland.; Department of Clinical Neurosciences, University of Helsinki, Helsinki, Finland., Hedner J; Sleep and Vigilance Laboratory, Department of Internal Medicine, University of Göteborg, Sahlgrenska University Hospital, University of Göteborg, Göteborg, Sweden., Saaresranta T; Sleep Research Center, Department of Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland.; Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland., Georgiev O; Pulmonology Unit, Department of Internal Medicine, Alexandrovska Hospital Medical University, Sofia, Bulgaria., Tiholov R; Department of Internal Diseases, Sveti Ivan Rilski Multiprofile Hospital for Active Treatment, Kozloduy, Bulgaria., Lecomte I; Bioprojet, 30 rue Francs Bourgois, Paris, France., Tamisier R; Hypoxia-Physiopathology (HP2) Laboratory, INSERM U1042, University Grenoble Alpes, Grenoble, France; and.; Cardio-Respiratory Functional Exploration Laboratory (EFCR), Grenoble Alpes University Hospital, Grenoble, France., Lévy P; Hypoxia-Physiopathology (HP2) Laboratory, INSERM U1042, University Grenoble Alpes, Grenoble, France; and.; Cardio-Respiratory Functional Exploration Laboratory (EFCR), Grenoble Alpes University Hospital, Grenoble, France., Scart-Gres C; Bioprojet, 30 rue Francs Bourgois, Paris, France., Lecomte JM; Bioprojet, 30 rue Francs Bourgois, Paris, France., Schwartz JC; Bioprojet, 30 rue Francs Bourgois, Paris, France., Pépin JL; Hypoxia-Physiopathology (HP2) Laboratory, INSERM U1042, University Grenoble Alpes, Grenoble, France; and.; Cardio-Respiratory Functional Exploration Laboratory (EFCR), Grenoble Alpes University Hospital, Grenoble, France.

Publikováno v: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2020 May 01; Vol. 201 (9), pp. 1135-1145.