Normal p53 status and function despite the development of drug resistance in human breast cancer cells

Autor: Wosikowski K, Jt, Regis, Rw, Robey, Alvarez M, Jeroen Buters, Jm, Gudas, Se, Bates

Publikováno v: Europe PubMed Central

Loss of or mutations in p53 protein have been shown to decrease both radio- and chemosensitivity. The present study assessed the p53 gene status, ability to arrest in G1 of the cell cycle, the functionality of the p53 transduction pathway, and apopto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2f631ffee206985a2f4fdac6b8adfc0
http://europepmc.org/abstract/med/8562478

Edaravone's reno-protective effects against chronic heat-stress exposure.

Autor: Alquraan LT; Department of Biological Sciences, The Faculty of Science, Yarmouk University, Irbid, Jordan., Alzoubi KH; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, UAE. khalzoubi@just.edu.jo.; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan. khalzoubi@just.edu.jo., Jaber S; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan., Khabour OF; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan., Al-Trad B; Department of Biological Sciences, The Faculty of Science, Yarmouk University, Irbid, Jordan., Al-Shwaheen A; Department of Biological Sciences, The Faculty of Science, Yarmouk University, Irbid, Jordan., Alomari G; Department of Biological Sciences, The Faculty of Science, Yarmouk University, Irbid, Jordan., Rababa'h SY; Department of Pharmacy, Faculty of Pharmacy, Jadara University, Irbid, Jordan., Masadeh MM; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Dec 03. Date of Electronic Publication: 2024 Dec 03.

Discovery of genes required for body axis and limb formation by global identification of retinoic acid–regulated epigenetic marks.

Autor: Berenguer, Marie¹ (AUTHOR), Meyer, Karolin F.¹ (AUTHOR), Yin, Jun² (AUTHOR), Duester, Gregg¹ (AUTHOR) duester@sbpdiscovery.org

Publikováno v: PLoS Biology. 5/18/2020, Vol. 18 Issue 5, p1-29. 29p. 2 Color Photographs, 2 Charts, 4 Graphs.

Retinoic acid signaling and bladder cancer: Epigenetic deregulation, therapy and beyond.

Autor: Ozgun, Gizem, Senturk, Serif, Erkek-Ozhan, Serap

Publikováno v: International Journal of Cancer; May2021, Vol. 148 Issue 10, p2364-2374, 11p

STRA6 Polymorphisms Are Associated With EGFR Mutations in Locally-Advanced and Metastatic Non-Small Cell Lung Cancer Patients.

Autor: Muñiz-Hernández, Saé, Velázquez-Fernández, Jesús Bernardino, Díaz-Chávez, José, Mondragón-Fonseca, Omar, Mayén-Lobo, Yerye, Ortega, Alberto, López-López, Marisol, Arrieta, Oscar

Publikováno v: Frontiers in Oncology; 11/24/2020, Vol. 11, pN.PAG-N.PAG, 10p