Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jlenia Guarnerio"'
Autor:
Marina T. Broz, Emily Y. Ko, Kristin Ishaya, Jinfen Xiao, Marco De Simone, Xen Ping Hoi, Roberta Piras, Basia Gala, Fernando H. G. Tessaro, Anja Karlstaedt, Sandra Orsulic, Amanda W. Lund, Keith Syson Chan, Jlenia Guarnerio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract T cell-based immunotherapies have exhibited promising outcomes in tumor control; however, their efficacy is limited in immune-excluded tumors. Cancer-associated fibroblasts (CAFs) play a pivotal role in shaping the tumor microenvironment and
Externí odkaz:
https://doaj.org/article/3c3fee63de4c4625909fa4b34fc910c7
Autor:
Mitchell Kamrava, Julie Jang, Emily Ko, Simon Knott, Tahir B Dar, Stephen L Shiao, Anthony T Nguyen, Jolene Viramontes, Satchel Stevens, Eric M Chung, Samuel Zhang, Katelyn M Atkins, Howard M Sandler, Jlenia Guarnerio, Zachary Zumsteg, David M Underhill
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff2179a1f4c745dca82f1dfc249ef9ac
Autor:
Emily Ko, Bonnie Balzer, Sandra Orsulic, Jlenia Guarnerio, Marina Broz, Kristin Ishaya, Jinfen Xiao, Marco DeSimone, Xen Ping Hoi, Roberta Piras, Basia Gala, Fernando HG Tessaro, Keith Syson Chan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3aa7ca5b5b614fe995a8c1165a023620
Autor:
Roberta Piras, Emily Y. Ko, Connor Barrett, Marco De Simone, Xianzhi Lin, Marina T. Broz, Fernando H. G. Tessaro, Mireia Castillo-Martin, Carlos Cordon-Cardo, Helen S. Goodridge, Dolores Di Vizio, Mona Batish, Kate Lawrenson, Y. Grace Chen, Keith Syson Chan, Jlenia Guarnerio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Circular RNAs can contribute to tumour progression. Here the authors show that two circular RNAs, circCsnk1g3 and circAnkib1 promote sarcoma growth by controlling the expression of interferon related genes and pro-inflammatory factors in sarcoma cell
Externí odkaz:
https://doaj.org/article/ce63810cc8a74cdea3778e236afde9f9
Autor:
Fotis Nikolos, Kazukuni Hayashi, Xen Ping Hoi, Mark Ellie Alonzo, Qianxing Mo, Armine Kasabyan, Hideki Furuya, Jane Trepel, Dolores Di Vizio, Jlenia Guarnerio, Dan Theodorescu, Charles Rosser, Andrea Apolo, Matthew Galsky, Keith Syson Chan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Chemoimmunotherapy recently failed to improve objective response for patients with advanced muscle-invasive bladder cancer (MIBC). Here using two murine models of immune-excluded MIBC, the authors show that resistance to chemoimmunotherapy can be ove
Externí odkaz:
https://doaj.org/article/176073b4ee2c4398bc3a707bca588745
Autor:
Jlenia Guarnerio, Lourdes Maria Mendez, Noboru Asada, Archita Venugopal Menon, Jacqueline Fung, Kelsey Berry, Paul S. Frenette, Keisuke Ito, Pier Paolo Pandolfi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Persistence of resistant leukemic cells after therapy is the main cause of relapse. Here, the authors show that mesenchymal stem cells-derived PML is involved in the maintenance of leukemia cells through Cxcl1 and IL6 and that PML inhibition enhances
Externí odkaz:
https://doaj.org/article/342cc2d1a19c42458ab298d79230142d
Autor:
Jlenia Guarnerio, Nadia Coltella, Ugo Ala, Giovanni Tonon, Pier Paolo Pandolfi, Rosa Bernardi
Publikováno v:
Stem Cell Reports, Vol 2, Iss 6, Pp 794-809 (2014)
Maintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-autonomous and non-cell-autonomous mechanisms within specialized bone marrow microenvironments. Recent evidence demonstrates that signaling by HIF-1α contri
Externí odkaz:
https://doaj.org/article/808fae5bfcbd44fca8ddbe16bbbf8055
Autor:
Nadia Coltella, Stefano Percio, Roberta Valsecchi, Roberto Cuttano, Jlenia Guarnerio, Maurilio Ponzoni, Pier Paolo Pandolfi, Giovanni Melillo, Linda Pattini, Rosa Bernardi
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 5, Pp 640-650 (2014)
Abstract Acute promyelocytic leukemia (APL) is epitomized by the chromosomal translocation t(15;17) and the resulting oncogenic fusion protein PML‐RARα. Although acting primarily as a transcriptional repressor, PML‐RARα can also exert functions
Externí odkaz:
https://doaj.org/article/31a3e7fe7bc94b6796ee63b9a09c16e2
Autor:
Pier Paolo Pandolfi, Andrea Lunardi, Carlos Cordon-Cardo, Mireia Castillo-Martin, Roderick T. Bronson, Rosa Bernardi, Paolo Sportoletti, Min Sup Song, Robin M. Hobbs, Guocan Wang, Takahiro Maeda, Riccardo Taulli, Luisa Riccardi, Jlenia Guarnerio
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d620f754290e21262275036a9eeaf1e0
https://doi.org/10.1158/2159-8290.22530062
https://doi.org/10.1158/2159-8290.22530062
Autor:
Pier Paolo Pandolfi, Andrea Lunardi, Carlos Cordon-Cardo, Mireia Castillo-Martin, Roderick T. Bronson, Rosa Bernardi, Paolo Sportoletti, Min Sup Song, Robin M. Hobbs, Guocan Wang, Takahiro Maeda, Riccardo Taulli, Luisa Riccardi, Jlenia Guarnerio
Supplementary Figure S1. Candidate genes that couple with p53 loss to transform MSCs. Supplementary Figure S2. Lrf plays as oncosuppressor triggering tumorigenesis in MSCs. Supplementary Figure S3. Lrf expression does not affect the CFU-F capacities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269f6ca1e7f74a0e3438f5c51c2c287f
https://doi.org/10.1158/2159-8290.22530059.v1
https://doi.org/10.1158/2159-8290.22530059.v1