Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jiyun Peng"'
Autor:
Tian Zhou, Yuxin Li, Xiaoyu Li, Fanzhuo Zeng, Yanxia Rao, Yang He, Yafei Wang, Meizhen Liu, Dali Li, Zhen Xu, Xin Zhou, Siling Du, Fugui Niu, Jiyun Peng, Xifan Mei, Sheng-Jian Ji, Yousheng Shu, Wei Lu, Feifan Guo, Tianzhun Wu, Ti-Fei Yuan, Ying Mao, Bo Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Microglia are professional phagocytes in the CNS. However, which cells scavenge corpses of microglia is largely neglected. Peng and colleagues found that nonprofessional phagocytes (astrocyte) phagocytose the debris of professional phagocytes (microg
Externí odkaz:
https://doaj.org/article/d6e7d054ad5143fa9bf9501f7b92f302
Autor:
Nan Gu, Min-Hee Yi, Madhuvika Murugan, Manling Xie, Sebastian Parusel, Jiyun Peng, Ukpong B. Eyo, Christine L. Hunt, Hailong Dong, Long-Jun Wu
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-19 (2022)
Abstract Microglia are highly dynamic immune cells of the central nervous system (CNS). Microglial processes interact with neuronal elements constantly on the order of minutes. The functional significance of this acute microglia-neuron interaction an
Externí odkaz:
https://doaj.org/article/ca2856cf259e4748b8e63effb6e058f4
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/63323712495b44028b2b98e5eecdd546
Autor:
Jiyun Peng, Min-Hee Yi, Heejin Jeong, Przemyslaw Peter McEwan, Jiaying Zheng, Gongxiong Wu, Shashank Ganatra, Yi Ren, Jason R. Richardson, Seog Bae Oh, Long-Jun Wu
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Activation of spinal cord microglia contributes to the development of peripheral nerve injury-induced neuropathic pain. However, the molecular mechanisms underlying microglial function in neuropathic pain are not fully understood. We identif
Externí odkaz:
https://doaj.org/article/bc74ac4668b044a1a817f242f168918e
Autor:
Jiyun Peng, Yong Liu, Anthony D. Umpierre, Manling Xie, Dai-Shi Tian, Jason R. Richardson, Long-Jun Wu
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract The P2Y12 receptor (P2Y12R) is a purinoceptor that is selectively expressed in microglia in the central nervous system. As a signature receptor, microglial P2Y12R mediates process chemotaxis towards ADP/ATP gradients and is engaged in severa
Externí odkaz:
https://doaj.org/article/fbc859ce197e440b93d43423bcf612b0
Autor:
Dale B. Bosco, Jiaying Zheng, Zhiyan Xu, Jiyun Peng, Ukpong B. Eyo, Ke Tang, Cheng Yan, Jun Huang, Lijie Feng, Gongxiong Wu, Jason R. Richardson, Hui Wang, Long-Jun Wu
Publikováno v:
Molecular Brain, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Microglia have been shown to be of critical importance to the progression of temporal lobe epilepsy. However, the broad transcriptional changes that these cells undergo following seizure induction is not well understood. As such, we utilized
Externí odkaz:
https://doaj.org/article/2edf870c16534658ade9b3a32465def5
Autor:
Li-Jun Zhou, Jiyun Peng, Ya-Nan Xu, Wei-Jie Zeng, Jun Zhang, Xiao Wei, Chun-Lin Mai, Zhen-Jia Lin, Yong Liu, Madhuvika Murugan, Ukpong B. Eyo, Anthony D. Umpierre, Wen-Jun Xin, Tao Chen, Mingtao Li, Hui Wang, Jason R. Richardson, Zhi Tan, Xian-Guo Liu, Long-Jun Wu
Publikováno v:
Cell Reports, Vol 27, Iss 13, Pp 3844-3859.e6 (2019)
Summary: Spinal long-term potentiation (LTP) at C-fiber synapses is hypothesized to underlie chronic pain. However, a causal link between spinal LTP and chronic pain is still lacking. Here, we report that high-frequency stimulation (HFS; 100 Hz, 10 V
Externí odkaz:
https://doaj.org/article/e5decdde04be4f0d9095a9df43c77fc2
Autor:
Nan Gu, Jiyun Peng, Madhuvika Murugan, Xi Wang, Ukpong B. Eyo, Dongming Sun, Yi Ren, Emanuel DiCicco-Bloom, Wise Young, Hailong Dong, Long-Jun Wu
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 605-614 (2016)
Peripheral nerve injury causes neuropathic pain accompanied by remarkable microgliosis in the spinal cord dorsal horn. However, it is still debated whether infiltrated monocytes contribute to injury-induced expansion of the microglial population. Her
Externí odkaz:
https://doaj.org/article/294fafb5d8154b23a4ebe9ff2309c43a
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Microglia and monocytes contribute to neuropathic pain states, but the precise role of the two cell types is not clear. Here Peng et al.use temporally controlled ablation of monocytes and microglia in mice to show that these cells work together to in
Externí odkaz:
https://doaj.org/article/718c07a2fe284ea1b1b6c6e085269f46
Autor:
Xuping Feng, Chenliang Yu, Yue Chen, Jiyun Peng, Lanhan Ye, Tingting Shen, Haiyong Wen, Yong He
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
The development of transgenic glyphosate-tolerant crops has revolutionized weed control in crops in many regions of the world. The early, non-destructive identification of superior plant phenotypes is an important stage in plant breeding programs. He
Externí odkaz:
https://doaj.org/article/d9100ad661ff45dbbd6bd3f7995be655