Výsledky vyhledávání

Improved sensitivity in identification of first recurrences of metastatic breast cancer with a combination of cell and cell-free liquid biopsy analysis

Autor: Giuseppe Di Caro, David Bourdon, Jiyun Byun, Tatjana Singer, Amanda Anderson, Martin Blankfard, Alisa Tubbs, Rick Wenstrup

Publikováno v: Journal of Clinical Oncology. 40:e13003-e13003

e13003 Background: Liquid biopsy analysis detecting circulating tumor cells (CTC) or circulating tumor DNA (ctDNA) is a non-invasive approach that may provide clinically actionable information for patients’ (pts) treatment decisions when convention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f782582732e0de8546c8b758809e5b3b
https://doi.org/10.1200/jco.2022.40.16_suppl.e13003

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Demonstration of the value of liquid biopsy to identify metastatic breast cancer: Comparison and combination of cell and cell-free platforms

Autor: Giuseppe Di Caro, David Bourdon, Jiyun Byun, Tatjana Singer, Amanda Anderson, Alisa Tubbs, Martin Blankfard, Rick Wenstrup

Publikováno v: Journal of Clinical Oncology. 40:e13004-e13004

e13004 Background: Liquid biopsy analysis detecting circulating tumor cells (CTC) or circulating tumor DNA (ctDNA) is a non-invasive approach that may provide clinically actionable information for patients’ (pts) treatment decisions when convention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cc3ec95a050ae41d66af038b45c74fb
https://doi.org/10.1200/jco.2022.40.16_suppl.e13004

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Circulating tumor cells (CTCs) with small-cell like pathology are prevalent in metastatic castration-resistant prostate cancer (mCRPC) and show selective pharmacodynamic reductions in patients treated with platinum but not ARSI or taxane

Autor: Joseph D. Schonhoft, Howard I. Scher, Rick Wenstrup, Emily Carbone, Audrey Gill, Samir Zaidi, Adam Jendrisak, Ethan Barnett, Anuradha Gopalan, Hannah Benoliel, Jiyun Byun

Publikováno v: Journal of Clinical Oncology. 38:5572-5572

5572 Background: The increasing availability and earlier use of life prolonging drugs targeting the androgen receptor signaling axis (ARSI) has resulted in an increase in the frequency of late state tumors with “small cell/neuroendocrine (NESC) phe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2d7477a00e8a5d746c197897d20bbe1
https://doi.org/10.1200/jco.2020.38.15_suppl.5572

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Abstract 4039: Simultaneous quantification of activated immune cells and PD-L1 expressing circulating tumor cells (CTCs) in peripheral blood of cancer patients receiving checkpoint inhibitor therapy

Autor: Rachel Krupa, Robin Richardson, Priscilla Ontiveros, Joseph Schonhoft, Jiyun Byun, David Lu, Sean Nisperos, Yipeng Wang, Mark Landers, Ryan Dittamore

Publikováno v: Cancer Research. 79:4039-4039

Purpose: Activated immune cell subpopulations and circulating tumor cells in patients receiving checkpoint inhibitor therapy were characterized with the aim of developing more sensitive diagnostic tools for prediction of immunotherapy response or res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc1e468357e3da4505f6efd269239042
https://doi.org/10.1158/1538-7445.am2019-4039

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Quantification of activated and exhausted immune cell populations and simultaneous characterization of circulating tumor cells (CTCs) in peripheral blood of cancer patients receiving checkpoint inhibitor therapy

Autor: Priscilla Ontiveros, Rachel Krupa, Robin Richardson, Ryan Dittamore, Jiyun Byun, Mark Landers, Gordon Vansant

Publikováno v: Journal of Clinical Oncology. 37:e14033-e14033

e14033 Background: Immune checkpoint inhibitors (ICIs) are becoming standard treatment options in many indications. However, a substantial portion of patients will not respond. Single biomarkers such as PD-L1 are insufficiently accurate to predict pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67764641879703044a8d3f84b204986e
https://doi.org/10.1200/jco.2019.37.15_suppl.e14033

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Abstract 5536: Simultaneous characterization and quantification of immune cell subpopulations and PD-L1 expressing CTCs in peripheral blood of cancer patients

Autor: Jiyun Byun, Mark Landers, Nadia Ebrahim, Angel Rodriguez, Ryon P. Graf, David S.K. Lu, Ryan Dittamore, Sean Nisperos, Yipeng Wang, Robin Richardson, Adam Jendrisak, Rachel Krupa

Publikováno v: Cancer Research. 78:5536-5536

Background: Expression of PD-L1 on tumor and immune markers in tumor tissue is associated with improved response to PD-1 and PD-L1 checkpoint inhibitors. However, each alone has limited predictive utility. Multimodal characterization of both the tumo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4891208b7a4d231327a4c704d4fa5df
https://doi.org/10.1158/1538-7445.am2018-5536

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Abstract A058: Simultaneous characterization of rare immune cell subpopulations and PD-L1-expressing CTCs in peripheral blood of cancer patients

Autor: Mark Landers, Ryan Dittamore, Angel Rodriguez, Yipeng Wang, Adam Jendrisak, Jiyun Byun, Nadia Ebrahim, Ryon P. Graf

Publikováno v: Molecular Cancer Therapeutics. 17:A058-A058

Background: Expression of PD-L1 on tumor and immune markers in tumor tissueis associated with improved response to PD-1 and PD-L1 checkpoint inhibitors. However, the PD-L1 biomarker has limited predictive utility. Multimodal characterization of both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35a058a0c68da01c1bdd0ef1ffa7216d
https://doi.org/10.1158/1535-7163.targ-17-a058

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'Columnlike' Structure of the Cross-Sectional Morphology of Bulk Heterojunction Materials

Autor: Shinuk Cho, Ji Sun Moon, Alan J. Heeger, Jae-Kwan Lee, Jiyun Byun

Publikováno v: Nano Letters. 9:230-234

The cross-sectional morphology of the bulk heterojunction (BHJ) films comprising regio-regular poly(3-hexylthiophene) (rrP3HT) and [6,6]-phenyl-C61 butyric acid methyl ester (PCBM) was observed with transmission electron microscopy (TEM). The cross-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4bab54698ebe63ae313457442f2c73
https://doi.org/10.1021/nl802821h

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Abstract 683: Quantification of rare PD-L1 expressing leukocytes and CTCs in peripheral blood of cancer patients

Autor: Mahipal Suraneni, Sarah Orr, Ryan Dittamore, Rachel Krupa, Mark Landers, Jiyun Byun, Adam Jendrisak, Yipeng Wang, Ryon P. Graf, David S.K. Lu

Publikováno v: Cancer Research. 77:683-683

Background: Expression of PD-L1 on tumor tissue is associated with improved response to PD-1 and PD-L1 checkpoint inhibitors. Additionally, expression of PD-L1 on infiltrating T cells is associated with immune exhaustion. Currently, PD-L1 analysis as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a5ee900bcbd00e7507ef0f19cc9bca1
https://doi.org/10.1158/1538-7445.am2017-683

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