Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jiyoun Nam"'
Autor:
Jair L Siqueira-Neto, Ok-Ryul Song, Hyunrim Oh, Jeong-Hun Sohn, Gyongseon Yang, Jiyoun Nam, Jiyeon Jang, Jonathan Cechetto, Chang Bok Lee, Seunghyun Moon, Auguste Genovesio, Eric Chatelain, Thierry Christophe, Lucio H Freitas-Junior
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 5, p e675 (2010)
Drugs currently available for leishmaniasis treatment often show parasite resistance, highly toxic side effects and prohibitive costs commonly incompatible with patients from the tropical endemic countries. In this sense, there is an urgent need for
Externí odkaz:
https://doaj.org/article/ccd4fdb790414498a3983eca222dd7eb
Autor:
Jihyun Choi, Sujin Ahn, Moon Kyeong Ju, Dongsik Park, Yoonae Ko, Jinhwa Lee, Peter Sommer, Junghwan Kim, Jong Yeon Hwang, Suyeon Jo, Inhee Choi, Jeongjin Kwon, Tae-Hee Kim, Ahn Jiye, Sung-Jun Han, Junwon Kim, Michel Liuzzi, Jonathan Cechetto, Doohyun Lee, Jiyoun Nam, Eunjung Park
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:5473-5477
We identified a novel class of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine compounds as potent HIV-1 replication inhibitors serendipitously during the process of evaluation of triazolothienopyrimidine (TTPM) compounds. Herein, we report synthe
Autor:
Joo-Won Suh, Hanki Lee, Jinyeong Heo, Jinhua Cheng, David Shum, Vincent Delorme, Constantin Radu, Jiyoun Nam, Jichan Jang
Publikováno v:
SLAS discovery : advancing life sciences RD. 22(2)
The feasibility and relevance of screening a library of raw actinomycete extracts (ECUM library) for the identification of antituberculosis activities was assessed on 11,088 extracts using a multiple-screening approach. Each extract was first tested
Autor:
Sung-Jun Han, Eunjung Park, Dongsik Park, Tae-Hee Kim, Jinhwa Lee, Suyeon Jo, Michel Liuzzi, Doohyun Lee, Jiyoun Nam, Jeongjin Kwon, Sujin Ahn, Moon Kyeong Ju, Jong Yeon Hwang, Jonathan Cechetto, Jihyun Choi, Inhee Choi, Junwon Kim, Peter Sommer, Junghwan Kim, Yoonae Ko, Zaesung No, Ahn Jiye
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:153-157
We identified a novel class of triazolothienopyrimidine (TTPM) compounds as potent HIV-1 replication inhibitors during a high-throughput screening campaign that evaluated more than 200,000 compounds using a cell-based full replication assay. Herein,
Publikováno v:
Tetrahedron Letters. 44:7727-7730
Effective dynamic kinetic resolution in the nucleophilic substitution reactions of α-bromo amides derived from l -leucine and l -proline is described. The methodology is used with dibenzylamine as a nucleophile in the presence of TBAI and Et 3 N to
Publikováno v:
Tetrahedron. 59:2397-2401
An example of dynamic thermodynamic resolution in the nucleophilic substitution reactions of α-bromo esters with an oxygen nucleophile is described. Temperature controlled epimerization–substitution sequence provides a practical protocol for the p
Autor:
Sujin Ahn, Ryang Yeo Kim, Zaesung No, Saeyeon Lee, Jungjun Kim, Yoonae Ko, Sunhee Kang, Mooyoung Seo, Hwankyu Kang, Inhee Choi, Jiyoun Nam, Kiyean Nam, Seijin Park, Jeong Jea Seo, Jaeseung Kim, Jichan Jang, Hyungjun Kim, Kevin Pethe, Young-Mi Kim, Min Jung Seo
Publikováno v:
Journal of medicinal chemistry. 57(12)
A critical unmet clinical need to combat the global tuberculosis epidemic is the development of potent agents capable of reducing the time of multi-drug-resistant (MDR) and extensively-drug-resistant (XDR) tuberculosis therapy. In this paper, we repo
Autor:
Taegwon Oh, Young-Mi Kim, Dongsik Park, Yoojin Cho, Seung-Ae Yim, Priscille Brodin, Honggun Lee, Jan Jiricek, Zaesung No, Victoria Jones, Sang Nae Cho, Sujin Ahn, Ryangyeo Kim, Thierry Christophe, Se Yeon Kim, Seungbin Lim, Min Jung Seo, Pablo Bifani, Sung-Jun Han, Haejin Kwon, Seijin Park, Jonathan Cechetto, Jiyoun Nam, Junghwan Kim, Hee Kyoung Jeon, Jaeseung Kim, René Wintjens, John R. Walker, Mooyoung Seo, Jungjun Kim, Sunhee Kang, Adeline C. Y. Chua, Anne J. Lenaerts, Hang Ohuong Pham, Hwankyu Kang, Inhee Choi, Mary Jackson, Kevin Pethe, Kiyean Nam, Yoonae Ko, Yunhee Jang, Saeyeon Lee, Whitney Barnes, Ulf Nehrbass, Mahesh Nanjundappa, Sylvie Alonso, Bee Huat Tan, Marie Kempf, Srinivasa P. S. Rao, Ju-Young Jung, Soohyun Oh, Jichan Jang, Jinhwa Lee, Chun-Taek Oh, Jeong Jea Seo
Publikováno v:
Nature Medicine
Nature Medicine, Nature Publishing Group, 2013, 19 (9), pp.1157-1160. ⟨10.1038/nm.3262⟩
Nature Medicine, Nature Publishing Group, 2013, 19 (9), pp.1157-1160. ⟨10.1038/nm.3262⟩
International audience; New therapeutic strategies are needed to combat the tuberculosis pandemic and the spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) forms of the disease, which remain a serious public health challenge wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38059c467c4a55442a71d3dda7fd1c8
https://hal.univ-angers.fr/hal-03333814
https://hal.univ-angers.fr/hal-03333814
Autor:
Sujin Ahn, Hyoung Cheul Kim, Keumhyun Kim, Jonathan Cechetto, Zaesung No, Sunju Kong, Jong Yeon Hwang, Young-Mi Kim, Dongsik Park, Marc P. Windisch, Michel Liuzzi, Junwon Kim, Hee-Young Kim, Jeongjin Kwon, Myung Eun Lee, Suyeon Jo, Jinhwa Lee, Jiyoun Nam, Jihyun Choi, Eunjung Park, Soohyun Kim
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(24)
We describe a novel 7-aminopyrazolo[1,5-a]pyrimidine (7-APP) derivative as a potent hepatitis C virus (HCV) inhibitor. A series of 7-APPs was synthesized and evaluated for inhibitory activity against HCV in different cell culture systems. The synthes
Autor:
Young-Mi Kim, Sunju Kong, Jeongjin Kwon, Youngsam Park, Jonathan Cechetto, Jihyun Choi, Zaesung No, Taedong Ok, Wonyoung So, Hyoung Cheul Kim, Moon Kyeong Ju, Suyeon Jo, Tae-Hee Kim, Jiyoun Nam, Mina Jo, Changmin Park, Inhee Choi, Michel Liuzzi, Sung-Jun Han, Jinhwa Lee, Junwon Kim, Doohyun Lee, Jaewan Yoon, Peter Sommer, Junghwan Kim, Yoonae Ko
Publikováno v:
ACS medicinal chemistry letters. 3(8)
We identified a novel class of aryl-substituted triazine compounds as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) during a high-throughput screening campaign that evaluated more than 200000 compounds for antihuman immunodeficiency