Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jiyan Dong"'
Autor:
Shuaibo Wang, Ye Li, Xujie Sun, Jiyan Dong, Li Liu, Jingbo Liu, Ruanqi Chen, Feng Li, Tiange Chen, Xiang Li, Guotong Xie, Jianming Ying, Qiang Guo, Yousheng Mao, Lin Yang
Publikováno v:
Thoracic Cancer, Vol 15, Iss 7, Pp 519-528 (2024)
Abstract Background Several studies have proposed grading systems for risk stratification of early‐stage lung adenocarcinoma based on histological patterns. However, the reproducibility of these systems is poor in clinical practice, indicating the
Externí odkaz:
https://doaj.org/article/b288fe8da8504e0ba20ba40fc1c516f1
Autor:
Zicheng Zhang, Xujie Sun, Yutao Liu, Yibo Zhang, Zijian Yang, Jiyan Dong, Nan Wang, Jianming Ying, Meng Zhou, Lin Yang
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Small cell lung cancer (SCLC) is a highly aggressive malignancy characterized by rapid growth and early metastasis and is susceptible to treatment resistance and recurrence. Understanding the intra‐tumoral spatial heterogeneity in SCLC is
Externí odkaz:
https://doaj.org/article/93e0d99e563f43319be331130ef22947
Autor:
Yibo Zhang, Zijian Yang, Ruanqi Chen, Yanli Zhu, Li Liu, Jiyan Dong, Zicheng Zhang, Xujie Sun, Jianming Ying, Dongmei Lin, Lin Yang, Meng Zhou
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer characterized by rapid tumor growth and early metastasis. Accurate prediction of prognosis and therapeutic response is crucial for optimizing treatment strategies an
Externí odkaz:
https://doaj.org/article/874eaf4177e840118f6fefbb8d891f77
Autor:
Lin Yang, Zicheng Zhang, Jiyan Dong, Yibo Zhang, Zijian Yang, Yiying Guo, Xujie Sun, Junling Li, Puyuan Xing, Jianming Ying, Meng Zhou
Publikováno v:
Pharmacological Research, Vol 194, Iss , Pp 106844- (2023)
Small-cell lung cancer (SCLC) is generally considered a 'homogenous' disease, with little documented inter-tumor heterogeneity in treatment guidance or prognosis evaluation. The precise identification of clinically relevant molecular subtypes remains
Externí odkaz:
https://doaj.org/article/8fa5b62a796a4711b2ec253464ddd2a4
Autor:
Chunfang Hu, Jiyan Dong, Li Liu, Jingbo Liu, Xujie Sun, Fei Teng, Xin Wang, Jianming Ying, Junling Li, Puyuan Xing, Lin Yang
Publikováno v:
Thoracic Cancer, Vol 13, Iss 3, Pp 338-345 (2022)
Abstract Objective Small cell lung cancer (SCLC) is one of the most aggressive malignancies characterized by neuroendocrine (NE) differentiation. The Delta‐like protein 3 (DLL3), as a direct downstream target of ASCL1, is involved in NE differentia
Externí odkaz:
https://doaj.org/article/49bd90e5efe44e5db784b5bf994ae051
Autor:
Xujie Sun, Jinyao Zhang, Jiyan Dong, Li Liu, Xue Li, Puyuan Xing, Jianming Ying, Yiqun Che, Junling Li, Lin Yang
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101538- (2022)
Background: YAP1 (Yes-associated protein 1), an important effector of the Hippo pathway, acts as an oncogene and is overexpressed in various malignant tumors. However, the function and expression pattern of YAP1 in pulmonary large cell neuroendocrine
Externí odkaz:
https://doaj.org/article/efcc2c4eb9584fd1bdd830754f964732
Autor:
Jinyao Zhang, Xujie Sun, Li Liu, Jiyan Dong, Lei Deng, Xin Wang, Yiying Guo, Jianming Ying, Puyuan Xing, Junling Li, Lin Yang
Publikováno v:
Translational Oncology, Vol 19, Iss , Pp 101379- (2022)
Background: The roles of cancer stem cells (CSCs) and epithelial-mesenchymal transition (EMT) in solid tumors are well established. However, the interaction between CSCs and EMT in pulmonary large cell neuroendocrine carcinoma (LCNEC) remains unknown
Externí odkaz:
https://doaj.org/article/9b1d094602704150aa8fe4be32d5312c
Autor:
Yifan Shen, Li Liu, Zhihao Tang, Zongyi Chen, Guixiang Ma, Jiyan Dong, Xi Zhang, Lin Yang, Qingfeng Zheng
Publikováno v:
Proceedings of the AAAI Conference on Artificial Intelligence. 36:2207-2215
Image-based survival prediction models can facilitate doctors in diagnosing and treating cancer patients. With the advance of digital pathology technologies, the big whole slide images (WSIs) provide increasing resolution and more details for diagnos
Autor:
Li Liu, Jiacong Wei, F. Teng, Jiyan Dong, Jianming Ying, Puyuan Xing, Yixiang Zhu, Yiying Guo, Lin Yang, Junling Li, Jinyao Zhang
Publikováno v:
Human Pathology. 108:84-92
Summary The objective of this study was to analyze the clinical and pathological characteristics of patients with small cell lung cancer (SCLC) after curative surgery and to explore prognostic factors for disease-free survival (DFS) and overall survi
Autor:
Junling Li, Jinyao Zhang, Yiying Guo, Lin Yang, Jiyan Dong, Puyuan Xing, Li Liu, Jianming Ying, Xin Wang, Jiacong Wei
Publikováno v:
Thoracic Cancer
Background Small cell lung cancer (SCLC) is one of the most aggressive lung cancers. Treatment of SCLC has remained unchanged during the past decades. Preclinical studies have revealed ASCL1 as a transcription regulator in the neuroendocrine (NE) dif