Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Jixi Li"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-10 (2024)
Abstract Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zαβ domain, initiating downstream interactions with RIPK1 and RIPK3 via RHIM domains. This engagement leads to
Externí odkaz:
https://doaj.org/article/f9e767a115714bb893c8098707b89412
Autor:
Min Kang, Bo Tang, Jixi Li, Ziyan Zhou, Kang Liu, Rensheng Wang, Ziyan Jiang, Fangfang Bi, David Patrick, Dongin Kim, Anirban K. Mitra, Yang Yang-Hartwich
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/db69a23125d348d6bf46e45c02eec456
Autor:
Anke Chen, Ning Fang, Zhifei Zhang, Yiqing Wen, Yajie Shen, Yanjie Zhang, Lu Zhang, Guoping Zhao, Jin Ding, Jixi Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The global outbreak of Mpox, caused by the monkeypox virus (MPXV), has attracted international attention and become another major infectious disease event after COVID-19. The mRNA cap N7 methyltransferase (RNMT) of MPXV methylates the N7 position of
Externí odkaz:
https://doaj.org/article/7fdb89495c484c408682af4f1d531f0b
Autor:
Zhidong Hu, Jingxian Xia, Juan Wu, Huimin Zhao, Ping Ji, Ling Gu, Wenfei Gu, Zhenyan Chen, Jinchuan Xu, Xuejiao Huang, Jian Ma, Anke Chen, Jixi Li, Tsugumine Shu, Xiao-Yong Fan
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
ABSTRACTOne-quarter of the world’s population is infected with Mycobacterium tuberculosis (Mtb). After initial exposure, more immune-competent persons develop asymptomatic latent tuberculosis infection (LTBI) but not active diseases, creates an ext
Externí odkaz:
https://doaj.org/article/469d8aafc6744a2795e88651888426ea
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Gasdermin-E (GSDME), the executioner of pyroptosis when cleaved by caspase 3, plays a crucial role in tumor defense and the response to chemotherapy drugs in cells. So far, there are poorly known mechanisms for the expression regulation of G
Externí odkaz:
https://doaj.org/article/f0223ab67ab84941a9cd26bf5f4a420c
Autor:
Lu Geng, Wenqing Gao, Hexige Saiyin, Yuanyuan Li, Yu Zeng, Zhifei Zhang, Xue Li, Zuolong Liu, Qiang Gao, Ping An, Ning Jiang, Xiaofei Yu, Xiangjun Chen, Suhua Li, Lei Chen, Boxun Lu, Aiqun Li, Guoyuan Chen, Yidong Shen, Haibing Zhang, Mei Tian, Zhuohua Zhang, Jixi Li
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-21 (2023)
Abstract Parkinson’s disease (PD), one of the most devastating neurodegenerative brain disorders, is characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN) and deposits of α-synuclein aggregates. Currently, phar
Externí odkaz:
https://doaj.org/article/79ee10d8aa2f4485b33d230d91c6cd8d
Autor:
Xun Wang, Shuai Jiang, Shujun Jiang, Xiangnan Li, Jingwen Ai, Ke Lin, Shiyun Lv, Shixuan Zhang, Minghui Li, Jixi Li, Lili Dai, Zixin Hu, Wenhong Zhang, Yanliang Zhang, Pengfei Wang
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/ece49247366346ad9754c073682c4193
Autor:
Luyao Bao, Juan Hu, Bowen Zhan, Mingzhe Chi, Zhengyang Li, Sen Wang, Chan Shan, Zhaozhao Zhao, Yanchao Guo, Xiaoming Ding, Chaoneng Ji, Shengce Tao, Ting Ni, Xuelian Zhang, Guoping Zhao, Jixi Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Ribonucleases (RNases) are responsible for RNA metabolism. RNase J, the core enzyme of the RNA degradosome, plays an essential role in global mRNA decay. Emerging evidence showed that the RNase J of Mycobacterium tuberculosis (Mtb-RNase J) c
Externí odkaz:
https://doaj.org/article/02eddbab4a0e4d70845e9f34bff9a0f4
Publikováno v:
Molecules, Vol 29, Iss 9, p 2058 (2024)
Targeting translation factor proteins holds promise for developing innovative anti-tuberculosis drugs. During protein translation, many factors cause ribosomes to stall at messenger RNA (mRNA). To maintain protein homeostasis, bacteria have evolved v
Externí odkaz:
https://doaj.org/article/64e338ddf6a3465facc3cc8cb71b5b10
Autor:
Bowen Zhan, Yanqing Gao, Wenqing Gao, Ye Li, Zhengyang Li, Qi Qi, Xin Lan, Hongbo Shen, Jianhua Gan, Guoping Zhao, Jixi Li
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Crystal structures of M. tuberculosis elongation factors EF-Tu and EF-Ts in complex and GDP-bound Ef-Tu reveal the molecular basis of EF-Tu’s representative recycling and inactive forms in protein translation.
Externí odkaz:
https://doaj.org/article/1182dd9df4aa4d8897445c274f698e56