Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jiwei Ding"'
Autor:
Jiwei Ding, Shujie Wang, Qipeng Liu, Yuqing Duan, Tingting Cheng, Zhongjie Ye, Zhanding Cui, Ao Zhang, Qiuyu Liu, Zixiong Zhang, Ning Zhang, Qian Liu, Ni An, Jianyuan Zhao, Dongrong Yi, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Saisai Guo, Jinhui Wang, Chen Liang, Jinming Zhou, Shan Cen, Xiaoyu Li
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107968- (2023)
Summary: Long interspersed element 1 (LINE-1) is the only currently known active autonomous transposon in humans, and its retrotransposition may cause deleterious effects on the structure and function of host cell genomes and result in sporadic genet
Externí odkaz:
https://doaj.org/article/a874c567f5d344b7b3f7258a95bf08e8
Autor:
Saisai Guo, Xiaobo Lei, Yan Chang, Jianyuan Zhao, Jing Wang, Xiaojing Dong, Qian Liu, Zixiong Zhang, Lidan Wang, Dongrong Yi, Ling Ma, Quanjie Li, Yongxin Zhang, Jiwei Ding, Chen Liang, Xiaoyu Li, Fei Guo, Jianwei Wang, Shan Cen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drug
Externí odkaz:
https://doaj.org/article/ffbcda39b3154046b3276edad622a296
Autor:
Ling Ma, Yali Li, Ting Shi, Zhiling Zhu, Jianyuan zhao, Yongli Xie, Jiajia Wen, Saisai Guo, Jing Wang, Jiwei Ding, Chen Liang, Guangzhi Shan, Quanjie Li, Mei Ge, Shan Cen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114213- (2023)
The rapid emergence of highly transmissible SARS-CoV-2 variants poses serious threat to the efficacy of vaccines and neutralizing antibodies. Thus, there is an urgent need to develop new and effective inhibitors against SARS-CoV-2 and future outbreak
Externí odkaz:
https://doaj.org/article/cf6d0a1faf3f4c1a97ea9fd2173354f2
Publikováno v:
IEEE Access, Vol 10, Pp 59772-59781 (2022)
Insulator defect is one of the most important factors for the grid power transmission accidents. However, up till now, traditional insulator defect identification methods cannot meet the requirements of high-speed transmission and high pixel ratio ae
Externí odkaz:
https://doaj.org/article/89733902c55e42dab09b045c43125c47
Autor:
Zixiong Zhang, Ning Zhang, Saisai Guo, Qian Liu, Shujie Wang, Ao Zhang, Dongrong Yi, Jianyuan Zhao, Quanjie Li, Jing Wang, Yongxin Zhang, Ling Ma, Jiwei Ding, Shan Cen, Xiaoyu Li
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Long-interspersed element 1 (LINE-1) is an autonomous non-LTR retrotransposon. Its replication can cause mutation and rearrangement of host genomic DNA, which may result in serious genetic diseases. Host cells therefore developed defense strategies t
Externí odkaz:
https://doaj.org/article/483c79c1cfe9430ba22dcb9d992d3c53
Autor:
Yanni Kou, Shujie Wang, Yanjie Ma, Ning Zhang, Zixiong Zhang, Qian Liu, Yang Mao, Rui Zhou, Dongrong Yi, Ling Ma, Yongxin Zhang, Quanjie Li, Jing Wang, Jinhui Wang, Xile Zhou, Chunnian He, Jiwei Ding, Shan Cen, Xiaoyu Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Long interspersed nuclear element 1 (LINE-1) is a dominant autonomous retrotransposon in human genomes which plays a role in affecting the structure and function of somatic genomes, resulting in human disorders including genetic disease and cancer. L
Externí odkaz:
https://doaj.org/article/f921cc61a54747e2bc63936a128672c7
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Despite that most HIV-infected individuals experience progressive CD4+ T cell loss and develop AIDS, a minority of HIV-infected individuals remain asymptomatic and maintain high level CD4+ T cell counts several years after serocon
Externí odkaz:
https://doaj.org/article/d7e0436165314b2cb737d203496c856a
Autor:
Xiangling Cui, Rui Zhou, Chenchao Huang, Rongyu Zhang, Jing Wang, Yongxin Zhang, Jiwei Ding, Xiaoyu Li, Jinming Zhou, Shan Cen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Mounting evidence indicates that Zika virus (ZIKV) is closely related to neurological disorders such as microcephaly and Guillain-Barré syndrome. There are currently no effective vaccines and FDA-approved inhibitors against ZIKV infection. The flavi
Externí odkaz:
https://doaj.org/article/cc4bd219e6674d95ad1b0f52e9a65a46
Autor:
Congjie Zhai, Ling Ma, Zhixin Zhang, Jiwei Ding, Jing Wang, Yongxin Zhang, Xiaoyu Li, Fei Guo, Liyan Yu, Jinming Zhou, Shan Cen
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 7, Iss 5, Pp 571-582 (2017)
Human APOBEC3G (hA3G) is a cytidine deaminase which inhibits HIV-1 replication. The HIV-1 accessory protein viral infectivity factor (Vif) counteracts with hA3G by targeting it for proteasomal degradation. In this work, we constructed and optimized m
Externí odkaz:
https://doaj.org/article/f5876401a22448b2b96504d44540b2f5
Autor:
Jing Wang, Yongxin Zhang, Quanjie Li, Jianyuan Zhao, Dongrong Yi, Jiwei Ding, Fei Zhao, Siqi Hu, Jinming Zhou, Tao Deng, Xiaoyu Li, Fei Guo, Chen Liang, Shan Cen
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3295-3304.e4 (2019)
Summary: Long noncoding RNAs (lncRNAs) participate in host antiviral defense by modulating immune responses. However, it remains largely unexplored how viruses exploit interferon (IFN)-independent host lncRNAs to facilitate viral replication. Here, w
Externí odkaz:
https://doaj.org/article/e3420c6d81df4796941c7fde6da7068b