Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jiuyi Lu"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63353 (2013)
Smoothened (Smo) mediated Hedgehog (Hh) signaling plays an essential role in regulating embryonic development and postnatal tissue homeostasis. Aberrant activation of the Hh pathway contributes to the formation and progression of various cancers. In
Externí odkaz:
https://doaj.org/article/5ad50d91188746c7bfc0d1cce7ee1328
Autor:
Chuangxun Cheng, Jiuyi Lu
Publikováno v:
Journal of Number Theory. 245:187-202
Autor:
Anna Mae Diehl, Albert S. Baldwin, Steve S. Choi, Thiago A. Pereira, Blair R. Anderson, Wing-Kin Syn, Leandi Krüger, Guanhua Xie, Gamze Karaca, Gregory A. Michelotti, Marzena Swiderska-Syn, Jiuyi Lu, Yuping Chen, Cynthia D. Guy, Isaac S. Chan
PDF file - 54K, Related primer sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b8d2ec0b2169b14befff350b31cf6d
https://doi.org/10.1158/0008-5472.22395345
https://doi.org/10.1158/0008-5472.22395345
Autor:
Anna Mae Diehl, Albert S. Baldwin, Steve S. Choi, Thiago A. Pereira, Blair R. Anderson, Wing-Kin Syn, Leandi Krüger, Guanhua Xie, Gamze Karaca, Gregory A. Michelotti, Marzena Swiderska-Syn, Jiuyi Lu, Yuping Chen, Cynthia D. Guy, Isaac S. Chan
PDF file - 82K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3304070a7fc7230316683cf540b13403
https://doi.org/10.1158/0008-5472.22395348.v1
https://doi.org/10.1158/0008-5472.22395348.v1
Autor:
Anna Mae Diehl, Albert S. Baldwin, Steve S. Choi, Thiago A. Pereira, Blair R. Anderson, Wing-Kin Syn, Leandi Krüger, Guanhua Xie, Gamze Karaca, Gregory A. Michelotti, Marzena Swiderska-Syn, Jiuyi Lu, Yuping Chen, Cynthia D. Guy, Isaac S. Chan
PDF file - 127K, S1. Panc 10.05 cells do not generate functional Hh ligands. S2. Other malignant hepatoma lines can increase MF Hh and glycolytic activity. S3. Summary of glycolytic metabolism. S4. MF-derived lactate provides energy source for lipoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f58c258ea1f64c97b029fe142a172ee
https://doi.org/10.1158/0008-5472.22395351.v1
https://doi.org/10.1158/0008-5472.22395351.v1
Autor:
Chris Hwang, Jason Walther, Jiuyi Lu, Jean McLarty, Myles Hollenbach, Kevin Brower, Marcella Yu
Publikováno v:
Biotechnology journal. 14(2)
In this study, the authors compared the impacts of fed-batch and perfusion platforms on process and product attributes for IgG1- and IgG4-producing cell lines. A "plug-and-play" approach is applied to both platforms at bench scale, using commercially
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:2187-2191
The Wnt signal transduction pathway is dysregulated in many highly prevalent diseases, including cancer. Unfortunately, drug discovery efforts have been hampered by the paucity of targets and drug-like lead molecules amenable to drug discovery. Recen
Autor:
Thiago A. Pereira, Yuping Chen, Albert S. Baldwin, Wing-Kin Syn, Jiuyi Lu, Guanhua Xie, Blair R. Anderson, Gregory A. Michelotti, Cynthia D. Guy, Gamze Karaca, Anna Mae Diehl, Isaac S. Chan, Leandi Krüger, Marzena Swiderska-Syn, Steve S. Choi
Publikováno v:
Cancer Research. 72:6344-6350
Hepatocellular carcinoma (HCC) typically develops in cirrhosis, a condition characterized by Hedgehog (Hh) pathway activation and accumulation of Hh-responsive myofibroblasts. Although Hh signaling generally regulates stromal–epithelial interaction
Autor:
Wei Chen, Tama Evron, Jiuyi Lu, Marc G. Caron, Alison R. Meloni, Martin D. Burkhalter, Melanie Philipp
Publikováno v:
Journal of Biological Chemistry. 286:27676-27686
The G protein-coupled receptor (GPCR)-like molecule Smoothened (Smo) undergoes dynamic intracellular trafficking modulated by the microtubule associated kinase GRK2 and recruitment of β-arrestin. Of this trafficking, especially the translocation of
Autor:
Wei Chen, Cynthia D. Guy, Ayako Suzuki, Jiuyi Lu, Anna Mae Diehl, Fatima A. Rangwala, Manal F. Abdelmalek, James L. Burchette
Publikováno v:
The Journal of Pathology. 224:401-410
Ballooned hepatocytes distinguish non-alcoholic steatohepatitis (NASH) from steatosis. Such cells contain dilated endoplasmic reticulum and ubiquitin aggregates, characteristics of endoplasmic reticulum stress. Hepatocyte ballooning increases the ris