Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jiuyang Liu"'
Autor:
Pingting Ying, Can Chen, Zequn Lu, Shuoni Chen, Ming Zhang, Yimin Cai, Fuwei Zhang, Jinyu Huang, Linyun Fan, Caibo Ning, Yanmin Li, Wenzhuo Wang, Hui Geng, Yizhuo Liu, Wen Tian, Zhiyong Yang, Jiuyang Liu, Chaoqun Huang, Xiaojun Yang, Bin Xu, Heng Li, Xu Zhu, Ni Li, Bin Li, Yongchang Wei, Ying Zhu, Jianbo Tian, Xiaoping Miao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Genome-wide association studies have identified numerous variants associated with human complex traits, most of which reside in the non-coding regions, but biological mechanisms remain unclear. However, assigning function to the non-coding e
Externí odkaz:
https://doaj.org/article/d8da8d297471458a8d73ff9caa654f66
Autor:
Adam H. Tencer, Jiuyang Liu, Jing Zhu, Nathaniel T. Burkholder, Yi Zhang, Wenwen Wu, Brian D. Strahl, Tomohiko Ohta, Tatiana G. Kutateladze
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The E3 ubiquitin ligase HERC2 has been linked to neurological diseases and cancer, however it remains a poorly characterized human protein. Here, we show that the ZZ domain of HERC2 (HERC2ZZ) recognizes a mimetic of the Nt-R cargo degradatio
Externí odkaz:
https://doaj.org/article/003cc22de27043328acd94df25cb60e4
Autor:
Xingxing Dong, Yalong Yang, Jinxuan Hou, Weizhen Chen, Qianqian Yuan, Gaoran Xu, Jiuyang Liu, Chengxin Li, Gaosong Wu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundAnaplastic thyroid carcinoma (ATC) is a rare but extremely malignant tumor, with a rapid growth rate and early metastasis thus leading to poor survival of patients. The molecular mechanisms underlying these aggressive traits of ATC remain u
Externí odkaz:
https://doaj.org/article/733211a61db34d1d948ab73f4b3b2352
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101842- (2022)
Summary: Dusquetide is a next-generation IDR (innate defense regulator) targeting the major autophagy receptor protein SQSTM1/p62 and modulating the innate immune response. Here, we describe a protocol for determining dusquetide-binding sites of p62
Externí odkaz:
https://doaj.org/article/30dbda97bdc64ebd908c2ab0d5700d99
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Infiltration of macrophages in and around tumor nest represents one of the most crucial hallmarks during tumor progression. The mutual interactions with tumor cells and stromal microenvironment contribute to phenotypically polarization of tu
Externí odkaz:
https://doaj.org/article/1c07cde13b1446cda761a0d2116b74d2
Autor:
Yi Zhang, Kyle Brown, Yucong Yu, Ziad Ibrahim, Mohamad Zandian, Hongwen Xuan, Steven Ingersoll, Thomas Lee, Christopher C. Ebmeier, Jiuyang Liu, Daniel Panne, Xiaobing Shi, Xiaojun Ren, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The histone acetyltransferase p300 mostly localizes to active chromatin; however, some repressed genes marked with H3K27me3 are also bound by p300. Here the authors show p300 is capable of phase separation, which relies on its catalytic core, and tha
Externí odkaz:
https://doaj.org/article/3a76054979544d3892894768400ab8c1
Autor:
Brianna J. Klein, Suk Min Jang, Catherine Lachance, Wenyi Mi, Jie Lyu, Shun Sakuraba, Krzysztof Krajewski, Wesley W. Wang, Simone Sidoli, Jiuyang Liu, Yi Zhang, Xiaolu Wang, Becka M. Warfield, Andrew J. Kueh, Anne K. Voss, Tim Thomas, Benjamin A. Garcia, Wenshe R. Liu, Brian D. Strahl, Hidetoshi Kono, Wei Li, Xiaobing Shi, Jacques Côté, Tatiana G. Kutateladze
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Acetylation of histone H3K23 has emerged as an essential posttranslational modification, yet this epigenetic mark remains poorly understood. Here, the authors identify the native MORF complex as a histone H3K23-specific acetyltransferase and show tha
Externí odkaz:
https://doaj.org/article/78758c527c604e018605e9ed73ff1cd5
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100155- (2020)
Summary: Since its discovery, several ligands of the ZZ domain have been identified; however, molecular and structural information underlying binding of these ligands remains limited. Here, we describe a protocol for biochemical and structural analys
Externí odkaz:
https://doaj.org/article/1999bffcef3648f38844ca6383a956b9
Autor:
Jiuyang Liu, Chaoqun Huang, Chunwei Peng, Fei Xu, Yan Li, Yonemura Yutaka, Bin Xiong, Xiaojun Yang
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background To investigate the influence of fibroblast activation protein alpha (FAP) derived from cancer-associated fibroblasts (CAFs), as well as potential mechanism of epithelial mesenchymal transition (EMT), on gastric cancer (GC) progres
Externí odkaz:
https://doaj.org/article/6f987bcf94cc45b49497ee5714ecf62d
Autor:
Wenlou Liu, Linwei Wang, Jiuyang Liu, Jingping Yuan, Jiamei Chen, Han Wu, Qingming Xiang, Guifang Yang, Yan Li
Publikováno v:
Translational Oncology, Vol 9, Iss 6, Pp 521-530 (2016)
Despite the extensive application of multispectral imaging (MSI) in biomedical multidisciplinary researches, there is a paucity of data available regarding the implication of MSI in tumor prognosis prediction. We compared the behaviors of multispectr
Externí odkaz:
https://doaj.org/article/a67104ca7a3a4fe197680a1b5b3833f8