Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jiusong Sun"'
Autor:
Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedin C. Culhane, Jiusong Sun, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108879- (2024)
Summary: One of the major barriers that have restricted successful use of chimeric antigen receptor (CAR) T cells in the treatment of solid tumors is an unfavorable tumor microenvironment (TME). We engineered CAR-T cells targeting carbonic anhydrase
Externí odkaz:
https://doaj.org/article/0c2301842fd04b6197a7bca08f019c78
Autor:
Allison F. O’Neill, Evelyn M. Nguyen, Evelyn D. Maldonado, Matthew R. Chang, Jiusong Sun, Quan Zhu, Wayne A. Marasco
Publikováno v:
Antibodies, Vol 13, Iss 1, p 24 (2024)
Background: Ewing sarcoma is a rare tumor of the bone or soft tissues characterized by diffuse membranous staining for CD99. As this tumor remains incurable in the metastatic, relapsed, and refractory settings, we explored the downstream immune impli
Externí odkaz:
https://doaj.org/article/24871d08246d4aeba068e517403e57c6
Autor:
Ying Fu, Zhen Zhang, Jared Sheehan, Yuval Avnir, Callie Ridenour, Thomas Sachnik, Jiusong Sun, M. Jaber Hossain, Li-Mei Chen, Quan Zhu, Ruben O. Donis, Wayne A. Marasco
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
A major goal of vaccine design is to protect against a broad range of pathogen strains. Here the authors isolate a new broadly neutralizing antibody against influenza haemagglutinin from human memory B cells, and identify mutations that increase and
Externí odkaz:
https://doaj.org/article/bdbf5311bd834c67bd4c3bb2bd03af22
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14525 (2011)
Leukocyte adhesion to the vascular endothelium and subsequent transendothelial migration play essential roles in the pathogenesis of cardiovascular diseases such as atherosclerosis. The leukocyte adhesion is mediated by localized activation of the en
Externí odkaz:
https://doaj.org/article/3e54bbfabf0e493996372294250815f9
Autor:
Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedin C. Culhane, Jiusong Sun, David Braun, Toni Choueiri, Catherine Wu, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco
Chimeric antigen receptor (CAR) T cells are routinely used in the treatment of hematologic malignancies, but there are several barriers that have restricted their successful use in the treatment of solid tumors. It has been hypothesized that one of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7e5374365b6a4cc0ace42518f7c10f
Publikováno v:
Fire Technology. 53:947-966
When there are multiple openings with different heights in fire rooms after flashover, the spill flame acquires relatively high initial momentum due to strong buoyancy force compared to that in a fire room with only a single opening. The high initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e4cd952daf0a027739fbc573491572
https://doi.org/10.1007/s10694-016-0612-4
https://doi.org/10.1007/s10694-016-0612-4
Publikováno v:
Tunnelling and Underground Space Technology. 56:118-124
Smoke layer interface height is an important parameter in fire safety science. In this paper, a series of experiments were conducted in a 1/6th scale model tunnel for determining the smoke layer interface height in medium scale tunnel fire scenarios.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a585de05d89975f172595c1a8ed3c3
https://doi.org/10.1016/j.tust.2016.02.009
https://doi.org/10.1016/j.tust.2016.02.009
Publikováno v:
Applied Thermal Engineering. 102:1314-1319
This paper presents an experimental investigation to explore the effect of tunnel sidewall on flame characteristics and air entrainment factor of methanol pool fires with decreasing distance to the sidewall. Experimental results show that owing to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7435576ae70cb358bc84dd5451473700
https://doi.org/10.1016/j.applthermaleng.2016.03.025
https://doi.org/10.1016/j.applthermaleng.2016.03.025
Publikováno v:
Applied Thermal Engineering. 101:390-401
A set of experiments was conducted in a scaled building model with 12 floors to study the effect of different ventilation conditions on combustion characteristics in a compartment connected to a stairwell with single opening. The results show that wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e759075f8fe72fd124d70c24afc7e73
https://doi.org/10.1016/j.applthermaleng.2016.01.117
https://doi.org/10.1016/j.applthermaleng.2016.01.117
Autor:
Chang De Kuan, Jiusong Sun, Eloah Rabello Suarez, Jianhua Sui, Wayne A. Marasco, Quan Zhu, Sabina Signoretti, Gordon J. Freeman
Publikováno v:
Oncotarget
Advances in the treatment of metastatic clear cell renal cell carcinoma (ccRCC) have led to improved progression-free survival of many patients; however the therapies are toxic, rarely achieve durable long-term complete responses and are not curative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbee88660889ea7df341af0228062b4
https://doi.org/10.18632/oncotarget.9114
https://doi.org/10.18632/oncotarget.9114