Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jiun‑Wen Guo"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 8, p 2016 (2023)
(1) Background: Human keratinocytes and murine skin express various cytochrome P450 enzymes. These include cytochrome P450 3A4, which may participate in the metabolism of cytochrome P450 3A4 substrate drugs. Desoximetasone, a topical corticosteroid a
Externí odkaz:
https://doaj.org/article/bca49ed62bc74026b7e1a822cca49332
Autor:
Chi-Cheng Huang, Ming-Hung Shen, Shao-Kuan Chen, Shung-Haur Yang, Chih-Yi Liu, Jiun-Wen Guo, Kang-Wei Chang, Chi-Jung Huang
Publikováno v:
Journal of Advanced Research, Vol 22, Iss , Pp 7-20 (2020)
Tumor metastasis or recurrence often occurs in patients with curative resection of colorectal cancer (CRC). Placental-specific 8 (PLAC8), which has increased expression in stool, may be associated with CRC recurrence. Insights into the role of PLAC8
Externí odkaz:
https://doaj.org/article/e5b647c0a5d846e1aa6efca5646f1de7
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6172 (2022)
(1) Background: Psoriasis is a T helper 1/T helper 17 cells-involved immune-mediated genetic disease. Lithospermic acid, one of the major phenolic acid compounds of Danshen, has antioxidation and anti-inflammation abilities. Due to the inappropriate
Externí odkaz:
https://doaj.org/article/c1039efb7f594d81ae4925ba3af8b1ad
Autor:
Jiun-Wen Guo, Shiou-Hwa Jee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6078 (2021)
Skin barrier functions, environmental insults, and genetic backgrounds are intricately linked and form the basis of common inflammatory skin disorders, such as atopic dermatitis, psoriasis, and seborrheic dermatitis, which may seriously affect one’
Externí odkaz:
https://doaj.org/article/73788e7ce8fa445ebdc3a392c252f79e
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 737 (2020)
Magnolol, which is a CYP3A substrate, is a well-known agent that can facilitate neuroprotection and reduce ischemic brain damage. However, a well-controlled release formulation is needed for the effective delivery of magnolol due to its poor water so
Externí odkaz:
https://doaj.org/article/d897fb2df9cf4b10a2fa9273cec54150
Autor:
Jiun-Wen Guo, Yu-Pin Cheng, Chih-Yi Liu, Haw-Yueh Thong, Chi-Jung Huang, Yang Lo, Chen-Yu Wu, Shiou-Hwa Jee
Publikováno v:
Pharmaceutics, Vol 12, Iss 5, p 457 (2020)
Psoriasis is a chronic inflammatory skin disorder with a pathogenesis involving the interleukin-23/interleukin-17 axis. Salvianolic acid B exerts several pharmacological effects, such as antioxidation, anti-inflammation, and antitumor effects. The an
Externí odkaz:
https://doaj.org/article/b5d34f6c4f3b40d786aef54d2a8d81fc
Autor:
Jiun-Wen Guo, 郭俊文
89
The main aim of this study is to explore the protection mechanism of glial-derived neurotrophic factor (GDNF) during excitotoxicity in hippocampus by kainic acid (KA). After microinjected with KA for 15 minutes, the excitotoxicity was induced
The main aim of this study is to explore the protection mechanism of glial-derived neurotrophic factor (GDNF) during excitotoxicity in hippocampus by kainic acid (KA). After microinjected with KA for 15 minutes, the excitotoxicity was induced
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/28185703906697467768
Autor:
Ming Hung Shen, Chih-Yi Liu, Chi Cheng Huang, Shung Haur Yang, Jiun‑Wen Guo, Chi Jung Huang, Shao Kuan Chen, Kang Wei Chang
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 22, Iss, Pp 7-20 (2020)
Journal of Advanced Research, Vol 22, Iss, Pp 7-20 (2020)
Graphical abstract
Highlights • Genes from stools have molecular significance with CRC tumorgenesis. • SCFAs, the metabolites of microbiota, can suppress CRC tumorigenesis. • Relationship between colonic genes, gut microbiota, or their met
Highlights • Genes from stools have molecular significance with CRC tumorgenesis. • SCFAs, the metabolites of microbiota, can suppress CRC tumorigenesis. • Relationship between colonic genes, gut microbiota, or their met
Publikováno v:
Pharmaceutics, Vol 12, Iss 737, p 737 (2020)
Pharmaceutics
Volume 12
Issue 8
Pharmaceutics
Volume 12
Issue 8
Magnolol, which is a CYP3A substrate, is a well-known agent that can facilitate neuroprotection and reduce ischemic brain damage. However, a well-controlled release formulation is needed for the effective delivery of magnolol due to its poor water so