Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jiujiao Gao"'
Autor:
He Liu, Meisuo Liu, Xibao Tian, Haina Wang, Jiujiao Gao, Hanrui Li, Zhehuan Zhao, Yu Liu, Caigang Liu, Xuan Chen, Yongliang Yang
Publikováno v:
eLife, Vol 12 (2023)
Background: The overactivation of NF-κB signaling is a key hallmark for the pathogenesis of extranodal natural killer/T cell lymphoma (ENKTL), a very aggressive subtype of non-Hodgkin’s lymphoma yet with rather limited control strategies. Previous
Externí odkaz:
https://doaj.org/article/cc948c2dee4b47448c7afef5dc1bc570
Publikováno v:
Tumor Biology, Vol 39 (2017)
Glycosylation of cell surface proteins plays an important role in the regulation of apoptosis. It has been demonstrated that knockdown of epithelial cell adhesion molecule promoted apoptosis, inhibited cell proliferation, and caused cell-cycle arrest
Externí odkaz:
https://doaj.org/article/50001b5e7810483fb13272aaf0d7139f
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102590 (2014)
Resistance to fluoropyrimidine-based chemotherapy is the main reason for the failure of cancer treatment, and drug resistance is associated with an inability of tumor cells to undergo apoptosis in response to treatment. Alterations in the expression
Externí odkaz:
https://doaj.org/article/4cad738e74994dfb985de9137fc59fc3
Autor:
He Liu, Meishuo Liu, Xibao Tian, Haina Wang, Jiujiao Gao, Hanrui Li, Zhehuan Zhao, Yu Liu, Caigang Liu, Xuan Chen, Yongliang Yang
BackgroundThe overactivation of NF-κB signaling is a key hallmark for the pathogenesis of extranodal natural killer/T cell lymphoma (ENKTL), a very aggressive subtype of non-Hodgkin’s lymphoma yet with rather limited control strategies. Previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23baf972c75918990bc93d9d8fd90fc3
https://doi.org/10.1101/2022.12.06.519362
https://doi.org/10.1101/2022.12.06.519362
Autor:
Caigang, Liu, Yixiao, Zhang, Jiujiao, Gao, Qi, Zhang, Lisha, Sun, Qingtian, Ma, Xinbo, Qiao, Xinnan, Li, Jinchi, Liu, Jiawen, Bu, Zhan, Zhang, Ling, Han, Dongyu, Zhao, Yongliang, Yang
Publikováno v:
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. 66
Breast cancer stem-like cells (BCSCs) have been suggested as the underlying cause of tumor recurrence, metastasis and drug resistance in triple-negative breast cancer (TNBC). Here, we report the discovery and biological evaluation of a highly potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c0d1cf1881a9822d8115c046c821992
https://pubmed.ncbi.nlm.nih.gov/36463808
https://pubmed.ncbi.nlm.nih.gov/36463808
Autor:
Caigang Liu, Yixiao Zhang, Jiujiao Gao, Qi Zhang, Lisha Sun, Qingtian Ma, Xinbo Qiao, Xinnan Li, Jinchi Liu, Jiawen Bu, Zhan Zhang, Ling Han, Dongyu Zhao, Yongliang Yang
Publikováno v:
Drug Resistance Updates. 66:100903
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe2b75334f2f7cfb5a733ad13e145ad9
https://doi.org/10.1016/j.drup.2022.100903
https://doi.org/10.1016/j.drup.2022.100903
Publikováno v:
Journal of Cellular Physiology. 235:3626-3633
Epithelial cell adhesion molecule (EpCAM), which is a transmembrane glycoprotein, is related to tumor progression. We demonstrated that EpCAM plays important roles in proliferation, apoptosis, and metastasis during breast cancer (BC) progression. But
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4cf37f99f419042cc89e3aeb969bd0
https://doi.org/10.1002/jcp.29252
https://doi.org/10.1002/jcp.29252
Publikováno v:
Traffic (Copenhagen, Denmark)REFERENCES. 22(7)
Dysregulation of the nuclear export machinery mediated by chromosomal maintenance 1 (CRM1, also known as exportin-1), is closely associated with various human disorders, such as breast cancer. Previously, we identified sulforaphene and its synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c613e8f857ef42c7d124732f88291c
https://pubmed.ncbi.nlm.nih.gov/34021516
https://pubmed.ncbi.nlm.nih.gov/34021516
Autor:
Xueliang Li, Minzhi Liang, Guohui Li, Yuqin Lei, Qingxiang Sun, Jin Chen, Feida Long, Huiying Chu, Jiali Gao, Xiangyu Long, Fangjun Wang, Meishuo Liu, Yongliang Yang, Cuixia Liu, Xibao Tian, Jiujiao Gao, Peng Chu
Publikováno v:
Journal of medicinal chemistry. 63(8)
Exportin-1 (also named as CRM1) plays a prominent role in autoimmune disorders and has emerged as a potential therapeutic target for colitis. Here we report on the rational structure-based discovery of a small-molecule antagonist of exportin-1, LFS-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f38dd1c0105626385a82ff7eeb03c74
https://pubmed.ncbi.nlm.nih.gov/32223194
https://pubmed.ncbi.nlm.nih.gov/32223194
Publikováno v:
Oncotarget
Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane protein that is expressed in the majority of normal epithelial tissues and is overexpressed in most epithelial cancers including breast cancer, where it plays an important role in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b57badd87866067e3d914d7d7578c2
https://doi.org/10.18632/oncotarget.4551
https://doi.org/10.18632/oncotarget.4551