Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jiuchun Zhang"'
Autor:
Yoko Shibata, Emily E. Mazur, Buyan Pan, Joao A. Paulo, Steven P. Gygi, Suyog Chavan, L. Sebastian Alexis Valerio, Jiuchun Zhang, Tom A. Rapoport
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The endoplasmic reticulum (ER) is shaped by abundant membrane curvature-generating proteins that include the REEP family member REEP5. The REEP1 subfamily, consisting of four proteins in mammals (REEP1-4), is less abundant and lack a N-termi
Externí odkaz:
https://doaj.org/article/65a6f1af4e0d4c628c2c71d3e810cabe
Autor:
Haining Zhou, Wenzhi Feng, Juntao Yu, Tiasha A. Shafiq, Joao A. Paulo, Jiuchun Zhang, Zhenhua Luo, Steven P. Gygi, Danesh Moazed
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112339- (2023)
Summary: The rixosome and PRC1 silencing complexes are associated with deSUMOylating and deubiquitinating enzymes, SENP3 and USP7, respectively. How deSUMOylation and deubiquitylation contribute to rixosome- and Polycomb-mediated silencing is not ful
Externí odkaz:
https://doaj.org/article/366a72c562284fd0af51b5dbf8b37530
Autor:
Saritha S. D'Souza, John Maufort, Akhilesh Kumar, Jiuchun Zhang, Kimberley Smuga-Otto, James A. Thomson, Igor I. Slukvin
Publikováno v:
Stem Cell Reports, Vol 6, Iss 2, Pp 243-256 (2016)
Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy, safety, a
Externí odkaz:
https://doaj.org/article/d0c6f8b8ad2a4675ad21598db45837a3
Autor:
Haining Zhou, Chad B. Stein, Tiasha A. Shafiq, Gergana Shipkovenska, Marian Kalocsay, Joao A. Paulo, Jiuchun Zhang, Zhenhua Luo, Steven P. Gygi, Karen Adelman, Danesh Moazed
Publikováno v:
Nature. 604:167-174
Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) are histone-modifying and -binding complexes that mediate the formation of facultative heterochromatin and are required for silencing of developmental genes and maintenance of cell fate1–3. Mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97261721a906d1cdf375220331886211
https://doi.org/10.1038/s41586-022-04598-0
https://doi.org/10.1038/s41586-022-04598-0
Autor:
Felix Kraus, Ellen A. Goodall, Ian R. Smith, Yizhi Jiang, Julia C. Paoli, Frank Adolf, Jiuchun Zhang, Joao A. Paulo, Brenda A. Schulman, J. Wade Harper
The protein kinase PINK1 and ubiquitin ligase Parkin promote removal of damaged mitochondria via a feed-forward mechanism involving ubiquitin (Ub) phosphorylation (pUb), Parkin activation, and ubiquitylation of mitochondrial outer membrane proteins t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b15dedd19bfa4a75d26b4141cf6ced8
https://doi.org/10.1101/2022.11.02.514817
https://doi.org/10.1101/2022.11.02.514817
Autor:
Mahtab Dastpak, Hyunmin Kim, Christina L. Paraggio, Claudia E. Leonard, Shanye Yin, Binkai Chi, Kelsey W. Nassar, R. Grant Rowe, Zhonggang Hou, Jiuchun Zhang, Erin F. Cohn, Na Yang, William Marion, Yosra Zhang, George Q. Daley, Robin Reed
Mutation of the essential splicing factor SF3B1 is primarily associated with hematological cancers but also occurs in solid tumors. We edited the most common mutation, K700E, into human embryonic stem (ES) cells to determine the effects of this mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2aacbf019327c01fb81bf37dde2267
https://doi.org/10.1101/2022.03.31.485699
https://doi.org/10.1101/2022.03.31.485699
Autor:
Tim Ahfeldt, J. Wade Harper, Heeseon An, Felix Kraus, Joao A. Paulo, Sookhee Park, Jiuchun Zhang, Alban Ordureau
Publikováno v:
Mol Cell
Cell state changes are associated with proteome remodeling to serve newly emergent cell functions. Here, we show that NGN2-driven conversion of human embryonic stem cells to induced neurons (iNeurons) is associated with increased PINK1-independent mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f2a9e467eb0548bf8cfcf5827309ef
https://europepmc.org/articles/PMC8688335/
https://europepmc.org/articles/PMC8688335/
Autor:
Jiuchun Zhang
This protocol is about making E8 medium for ES/iPS culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f8384782ac92bde4fb4651b13193a3
https://doi.org/10.17504/protocols.io.bsacnaaw
https://doi.org/10.17504/protocols.io.bsacnaaw
Autor:
Jiuchun Zhang
This protocol describes the electroporation of Cas9 protein into human pluripotent stem cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db51fc49e29c15545c6bddeac272688
https://doi.org/10.17504/protocols.io.br87m9zn
https://doi.org/10.17504/protocols.io.br87m9zn
Autor:
Jiuchun Zhang
This protocol is about human pluripotent stem cell culture. Some facts about human pluripotent stem cells They attach to several extra cellular matrices, including Matrigel, laminin, vitronectin, fibronectin and high-density RGD peptides. The best an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417c8b38847961bf7533cdafb73babca
https://doi.org/10.17504/protocols.io.br9cm92w
https://doi.org/10.17504/protocols.io.br9cm92w