Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jiu-Qiang Wang"'
Autor:
Xiao Li, Kai Cheng, Meng-Di Shang, Yong Yang, Bin Hu, Xi Wang, Xiao-Dan Wei, Yan-Chun Han, Xiao-Gang Zhang, Meng-Hua Dong, Zhen-Lin Yang, Jiu-Qiang Wang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background TBK1 positively regulates the growth factor-mediated mTOR signaling pathway by phosphorylating mTOR. However, it remains unclear how the TBK1-mTOR signaling pathway is regulated. Considering that STING not only interacts with TBK1
Externí odkaz:
https://doaj.org/article/c13acb335ac04ab9ae46c41fd07f1121
Autor:
Jian-Ping Ren, Hao-Long Cong, Li-Jie Gao, Dong-Fang Jiang, Xin-Tong Li, Yun Wang, Jiu-Qiang Wang, Tie-Shan Tang
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTAs a member of the pattern recognition receptors (PRRs) involving in the innate immune system, Toll-like receptors (TLRs) can sense a wide range of microbial pathogens and combat infections by producing antimicrobial products, inflammatory cy
Externí odkaz:
https://doaj.org/article/4813f9235dd64e1aad3b76c7dfe7b3eb
Autor:
Zhongshuai Sun, Qingyin Zheng, Xi Wang, Tie-Shan Tang, Haiyan Tan, Hao Chai, Jie Yu, Shu Zhu, Bing Zhang, Caixia Guo, Fengli Wang, Yang Li, Heng Wang, Yang Liu, Aimin Zhou, Quan Chen, Qiao Chu Wang, Maojun Yang, Yuxiu Yang, Xiaoling Li, Qiaoxia Zheng, Jiu Qiang Wang
Publikováno v:
Cell. 165:1454-1466
Summary Maintaining homeostasis of Ca 2+ stores in the endoplasmic reticulum (ER) is crucial for proper Ca 2+ signaling and key cellular functions. The Ca 2+ -release-activated Ca 2+ (CRAC) channel is responsible for Ca 2+ influx and refilling after
Autor:
Zhongshuai, Sun, Hui, Zhang, Xi, Wang, Qiao-Chu, Wang, Chuanchao, Zhang, Jiu-Qiang, Wang, Yi-Han, Wang, Chao-Qiang, An, Ke-Yan, Yang, Yun, Wang, Fei, Gao, Caixia, Guo, Tie-Shan, Tang
Publikováno v:
Cell death and differentiation. 25(9)
TMCO1 (transmembrane and coiled-coil domains 1) is an endoplasmic reticulum (ER) transmembrane protein that actively prevents Ca
Autor:
Xiaoling Li, Qiao-Chu Wang, Hui Zheng, Jiu-Qiang Wang, Junjie Fang, Yun Wang, X L Zhu, Caixia Guo, Min Huang, Fengli Wang, Lingyu Xing, Hongmei Liu, Yingfeng Tu, Zhongshuai Sun, Xi Wang, Xiaolu Ma, Juanjuan Gong, Tie-Shan Tang
Publikováno v:
Nucleic Acids Research
DNA damage response (DDR) is essential for genome stability and human health. Recently, several RNA binding proteins (RBPs), including fused-in-sarcoma (FUS), have been found unexpectedly to modulate this process. The role of FUS in DDR is closely li
Autor:
Tie-Shan Tang, Xiaolu Ma, Yun Wang, Xiaoling Li, Hongmei Liu, Min Huang, Jiu-Qiang Wang, Yingfeng Tu, Shu Zhu, Caixia Guo, Yang Liu, Hongyan Shen, Juanjuan Gong, X L Zhu, Qian Chen, Fengli Wang
Publikováno v:
Oncotarget
// Xuefei Zhu 1, * , Xiaolu Ma 2, * , Yingfeng Tu 1, * , Min Huang 2 , Hongmei Liu 1 , Fengli Wang 1 , Juanjuan Gong 1 , Jiuqiang Wang 1 , Xiaoling Li 1 , Qian Chen 1 , Hongyan Shen 2 , Shu Zhu 1 , Yun Wang 1 , Yang Liu 2 , Caixia Guo 2 , Tie-Shan Ta
Autor:
Fengli Wang, Xiwen Lin, You-Qi Liao, Wenjuan Xie, Dandan Wang, Shu Zhu, Tie-Shan Tang, Caixia Guo, Qinmiao Sun, Huai-Rong Luo, Jiu-Qiang Wang, Yun-Gui Yang, Chunsheng Han, Yeran Yang, Yong-Sheng Wu
Publikováno v:
Human Molecular Genetics. 22:3641-3653
5-Hydroxymethylcytosine (5-hmC) may represent a new epigenetic modification of cytosine. While the dynamics of 5-hmC during neurodevelopment have recently been reported, little is known about its genomic distribution and function(s) in neurodegenerat
Autor:
Qiao-Chu Wang, Caixia Guo, Heping Cheng, Xianhua Wang, Qian Chen, Yun Wang, Qinmiao Sun, Quan Chen, Jiu-Qiang Wang, Tie-Shan Tang
Publikováno v:
Journal of Biological Chemistry. 288:3070-3084
Huntington disease (HD) is an inherited, fatal neurodegenerative disorder characterized by the progressive loss of striatal medium spiny neurons. Indications of oxidative stress are apparent in brain tissues from both HD patients and HD mouse models;
Publikováno v:
Schizophrenia research. 193
Currently, numerous antipsychotic agents have been developed in the area of pharmacological treatment of schizophrenia. However, the molecular mechanism underlying multi targets of antipsychotics were yet to be explored. In this study we performed a
Autor:
Ying-li Shang, Su-su Qu, Lei Gao, Jiu-Qiang Wang, Hong-lei Sun, Xue-xin Gao, Yue Qu, Si-dang Liu
Publikováno v:
Oncotarget
// Xue-xin Gao 1, * , Lei Gao 2, * , Jiu-qiang Wang 3 , Su-su Qu 4 , Yue Qu 5 , Hong-lei Sun 6 , Si-dang Liu 7 , Ying-li Shang 7 1 Department of Thoracic Surgery, Central Hospital of Tai’an, Tai’an, Shandong, China 2 Department of Shandong Provin