Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jitka Yehudith Sagiv"'
Autor:
Avital Eisenberg-Lerner, Ron Benyair, Noa Hizkiahou, Neta Nudel, Roey Maor, Matthias P. Kramer, Merav D. Shmueli, Inbal Zigdon, Marina Cherniavsky Lev, Adi Ulman, Jitka Yehudith Sagiv, Molly Dayan, Bareket Dassa, Mercedes Rosenwald, Idit Shachar, Jie Li, Yanzhuang Wang, Nili Dezorella, Suman Khan, Ziv Porat, Eyal Shimoni, Ori Avinoam, Yifat Merbl
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Correct Golgi assembly is important to cellular homeostasis but regulation of its structure under stress remains unclear. Here, the authors identify stress-induced degradation of GM130 by Golgi-localized 26S proteasomes, leading to Golgi dispersal.
Externí odkaz:
https://doaj.org/article/ff1a3445dde44826a238fff8d76ba365
Autor:
Michal Dranitzki Elhalel, Mark L. Tykocinski, Noam Shani, Fanny Shkedy, Jitka Yehudith Sagiv, Liat Ben Gigi–Tamir, Yosi Meir Gozlan, Kobi Tzdaka, Tatyana B. Prigozhina, Alexandra Aronin, Shira Amsili, Efi Makdasi
Cytotoxic T-lymphocyte antigen 4 (CTLA4)-FasL, a homo-hexameric signal converter protein, is capable of inducing robust apoptosis in malignant cells of the B-cell lineage expressing its cognate B7 and Fas targets, while sparing nonmalignant ones. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8acdcf063baf664e37a78b4888b1cb1
https://doi.org/10.1158/1535-7163.c.6542272.v1
https://doi.org/10.1158/1535-7163.c.6542272.v1
Autor:
Michal Dranitzki Elhalel, Mark L. Tykocinski, Noam Shani, Fanny Shkedy, Jitka Yehudith Sagiv, Liat Ben Gigi–Tamir, Yosi Meir Gozlan, Kobi Tzdaka, Tatyana B. Prigozhina, Alexandra Aronin, Shira Amsili, Efi Makdasi
(a) Receptors expression on human cell lines and mouse BCL-1 splenocytes. (b) Anti CTLA4-FasL antibodies are formed in treated mice. (c) Neutralizing anti CTLA4-FasL antibodies are formed in treated mice.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b964846c2e67de8d26eac159f86a21bb
https://doi.org/10.1158/1535-7163.22519081.v1
https://doi.org/10.1158/1535-7163.22519081.v1
Autor:
Michal Dranitzki Elhalel, Mark L. Tykocinski, Noam Shani, Fanny Shkedy, Jitka Yehudith Sagiv, Liat Ben Gigi–Tamir, Yosi Meir Gozlan, Kobi Tzdaka, Tatyana B. Prigozhina, Alexandra Aronin, Shira Amsili, Efi Makdasi
Table S1. Summary of the Toxicokinetic Parameters of CTLA4-FasL in mouse Plasma at the first injection (Day 1) and the third injection (Day 5) Table S2. Summary of the Pharmacokinetic parameters in a single dose of CTLA4-FasL in Cynomolgus monkey pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c90efa3cfd76a11505c99d79171c4e
https://doi.org/10.1158/1535-7163.22519057.v1
https://doi.org/10.1158/1535-7163.22519057.v1
Autor:
Michal Dranitzki Elhalel, Mark L. Tykocinski, Noam Shani, Fanny Shkedy, Jitka Yehudith Sagiv, Liat Ben Gigi–Tamir, Yosi Meir Gozlan, Kobi Tzdaka, Tatyana B. Prigozhina, Alexandra Aronin, Shira Amsili, Efi Makdasi
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1700b3bdd4de82a3cc3d1d6b0fa0dc1e
https://doi.org/10.1158/1535-7163.22519060.v1
https://doi.org/10.1158/1535-7163.22519060.v1
Autor:
Ron Benyair, Neta Nudel, Nili Dezorella, Mercedes Rosenwald, Roey Maor, Avital Eisenberg-Lerner, Bareket Dassa, Matthias P. Kramer, Suman Khan, Marina Cherniavsky Lev, Inbal Zigdon, Adi Ulman, Molly Dayan, Idit Shachar, Eyal Shimoni, Yifat Merbl, Noa Hizkiahou, Yanzhuang Wang, Merav D. Shmueli, Jie Li, Ziv Porat, Ori Avinoam, Jitka Yehudith Sagiv
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The Golgi is a dynamic organelle whose correct assembly is crucial for cellular homeostasis. Perturbations in Golgi structure are associated with numerous disorders from neurodegeneration to cancer. However, whether and how dispersal of the Golgi app
Autor:
Alexandra Aronin, Shira Amsili, Yosi Gozlan, Liat Ben Gigi Tamir, Jitka Yehudith Sagiv, Fanny Shkedy, Tatyana B. Prigozhina, Michal Dranitzki Elhalel, Noam Shani, Efi Makdasi, Kobi Tzdaka, Mark L. Tykocinski
Publikováno v:
Molecular cancer therapeutics. 19(2)
Cytotoxic T-lymphocyte antigen 4 (CTLA4)-FasL, a homo-hexameric signal converter protein, is capable of inducing robust apoptosis in malignant cells of the B-cell lineage expressing its cognate B7 and Fas targets, while sparing nonmalignant ones. Thi