Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jitka Psotová"'
Autor:
Jaroslav Maceček, Hana Kolářová, Jitka Psotová, Robert Bajgar, Martin Huf, Pavla Nevřelová, Marek Tomečka, Jiří Mosinger
Publikováno v:
Acta Medica, Vol 47, Iss 4, Pp 327-329 (2004)
The aim of this study was analysis of DNA damage in the cell line of the human melanoma G361 after photodynamic therapy (PDT) by comet assay. Photodynamic therapy is based on cytotoxic action of sensitizers (10 µM ZnTPPS4 fixed into 1 mM cyclodextri
Externí odkaz:
https://doaj.org/article/8edad11ba8de4df3b3cbc8c7115a2eeb
Publikováno v:
Burns. 32:973-979
The administration of antioxidants has been shown to enhance repair and healing processes in cutaneous tissue. Silymarin, an extract from Silybum marianum has been reported to be beneficial in the treatment of chemically-induced oxidative stress in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8bebaf6511b829d97fd77761f74e150
https://doi.org/10.1016/j.burns.2006.04.004
https://doi.org/10.1016/j.burns.2006.04.004
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 84:167-174
UVA radiation provokes the generation of reactive oxygen species (ROS), which induce oxidative stress in the exposed cells leading to extensive cellular damage and cell death either by apoptosis or necrosis. One approach to protecting human skin agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f362c73ad447273a62c23eb3f89466
https://doi.org/10.1016/j.jphotobiol.2006.02.012
https://doi.org/10.1016/j.jphotobiol.2006.02.012
Autor:
Vladimír Křen, Marian Hajduch, Daniela Walterová, Jitka Psotová, Radek Gažák, Petr Sedmera, Petr Džubák, Alena Rajnochová Svobodová
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:3793-3810
Large series of O-alkyl derivatives (methyl and benzyl) of silybin and 2,3-dehydrosilybin was prepared. Selective alkylation of the silybin molecule was systematically investigated. For the first time we present here, for example, preparation of 19-n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6f56cb4a1e5444654279073b07b4b3
https://doi.org/10.1016/j.bmc.2006.01.035
https://doi.org/10.1016/j.bmc.2006.01.035
Autor:
Rostislav Vecera, Vilím Šimánek, Jitka Psotová, Borivoj Klejdus, Pavel Kosina, Jaroslav Vicar, Vlastimil Kuban, Jitka Ulrichová
Publikováno v:
Journal of Chromatography B. 830:165-172
Adult rats were orally administered with a single dose of sanguinarine (10 mg SA per 1 kg body weight) in 1.0 ml water. In the plasma and the liver, dihydrosanguinarine (DHSA) was identified as a SA metabolite by high performance liquid chromatograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9675de95ac2dee29c7edad2d937e400
https://doi.org/10.1016/j.jchromb.2005.10.030
https://doi.org/10.1016/j.jchromb.2005.10.030
Autor:
Věra Přikrylová, Alena Rajnochová Svobodová, Jitka Psotová, Petr Sedmera, Radek Gažák, Vladimír Křen, Daniela Walterová
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:5677-5687
Carboxylic acids derived from silybin (1) and 2,3-dehydrosilybin (2) with improved water solubility were prepared by selective oxidation of parent compounds and a new inexpensive method for preparation of 2,3-dehydrosilybin from silybin was developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5bccc33329684fb7567682ec6160d2
https://doi.org/10.1016/j.bmc.2004.07.064
https://doi.org/10.1016/j.bmc.2004.07.064
Publikováno v:
Phytotherapy Research. 18:107-110
Silymarin, an extract of flavonolignans from the dried fruits of milk thistle (Silybum marianum L. Gaertneri) and its constituents silibinin, dehydrosilibinin, silychristin and silydianin were tested for protective effects on rat cardiomyocytes expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ac6365df7db0e2c63c23940f35d8bc
https://doi.org/10.1002/ptr.1415
https://doi.org/10.1002/ptr.1415
Publikováno v:
Biomedical Papers. 147:147-153
Chelation, electrochemical, antioxidant and cytoprotective properties of six phenolics - cynarin and caffeic, chlorogenic, ferulic, protocatechuic and rosmarinic acids were studied on the following models: (i) chelation of transition metals, (ii) que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69ef0c2e19467a0d7169d7149a9d1ec
https://doi.org/10.5507/bp.2003.020
https://doi.org/10.5507/bp.2003.020
Publikováno v:
Biomedical Papers. 147:137-145
UV skin exposure induces extensive generation of reactive oxygen species (ROS). These can react with DNA, proteins, fatty acids and saccharides causing oxidative damage. Such injuries result in a number of harmful effects: disturbed cell metabolism,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca208ebd3d243f3aec815d34e42c7d5b
https://doi.org/10.5507/bp.2003.019
https://doi.org/10.5507/bp.2003.019
Publikováno v:
Phytotherapy Research. 17:1082-1087
The organic fraction (OF; 25.7% w/w of rosmarinic acid) of Prunella vulgaris (total extract) was found to exhibit the following: scavenging activity on diphenylpicrylhydrazyl radical (DPPH), inhibition of in vitro human LDL Cu(II)-mediated oxidation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320c5c21931fdfcf39e3f3bee22baa93
https://doi.org/10.1002/ptr.1324
https://doi.org/10.1002/ptr.1324