Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jitka Ourednik"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103025- (2024)
Summary: The Rice-Vannucci model in rodent pups is subject to substantial loss of animals, result inconsistency, and high lab-to-lab variability in extent and composition of induced injury. This protocol allows for highly predictable and reproducible
Externí odkaz:
https://doaj.org/article/ac4d03ed669946dfb5c8b52c9deee080
Autor:
Václav Ourednik Ph.D., Jitka Ourednik
Publikováno v:
Cell Transplantation, Vol 16 (2007)
It is hoped that stem cell biology will play a major role in the treatment of a number of so far incurable diseases via transplantation therapy. Today, we know that neural stem cell grafts not only represent a valuable source of missing cells and mol
Externí odkaz:
https://doaj.org/article/6819bd4cf77e4c938534f05839bf6d16
Autor:
Jitka Ourednik, Václav Ourednik
Publikováno v:
Cell Transplantation, Vol 13 (2004)
In this review we trace back the history of an idea that takes a new approach in restorative neurotransplantation by focusing on the “multifaceted dialogue” between graft and host and assigns a central role to graft-evoked host plasticity. In sev
Externí odkaz:
https://doaj.org/article/c15ba16c6b094f408dbb1ee05e0bde32
Publikováno v:
Stem Cells. 26:254-265
Recent studies indicate that transplanted neural stem/progenitor cells (NSPs) can interact with the environment of the central nervous system and stimulate protection and regeneration of host cells exposed to oxidative stress. Here, a set of animals
Publikováno v:
STEM CELLS. 24:2110-2119
Although the potential value of transplanted and endogenous neural stem cells (NSCs) for the treatment of the impaired central nervous system (CNS) has widely been accepted, almost nothing is known about their sensitivity to the hostile microenvironm
Autor:
Vaclav Ourednik, Richard L. Sidman, Evan Y. Snyder, Stephen Gullans, Kook In Park, Philip E. Stieg, Michael A. Hack, Jitka Ourednik, Francis E. Jensen, Booma D. Yandava, Jonathan D. Flax
Publikováno v:
Experimental Neurology. 199:156-178
Clonal neural cells with stem-like features integrate appropriately into the developing and degenerating central and peripheral nervous system throughout the neuraxis. In response to hypoxic-ischemic (HI) injury, previously engrafted, integrated, and
Publikováno v:
Annals of the New York Academy of Sciences. 1049:ix-xii
Publikováno v:
Annals of the New York Academy of Sciences. 1049:185-188
Here, we present our preliminary data showing that neural stem cells (NSCs) can prevent the degeneration of striatal neurons when transplanted into the CNS prior to intoxication with 3-nitropropionic acid (3-NP). In the adult CNS, the number of NSCs,
Autor:
Mahesh Lachyankar, Sahar Nisim, Richard L. Sidman, Jitka Ourednik, Evan Y. Snyder, Samia J. Khoury, Anthony Atala, René Yiou, Kook In Park, Jaime Imitola, Mark H. Tuszynski, Yang D. Teng, Franz Josef Mueller
Publikováno v:
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 359:823-837
The thesis advanced in this essay is that stem cells—particularly those in the nervous system—are components in a series of inborn ‘programs’ that not only ensure normal development, but persist throughout life so as to maintain homeostasis i
Publikováno v:
Nature Biotechnology. 20:1103-1110
We investigated the hypothesis that neural stem cells (NSCs) possess an intrinsic capacity to "rescue" dysfunctional neurons in the brains of aged mice. The study focused on a neuronal cell type with stereotypical projections that is commonly comprom