Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jitka, Sokolová"'
Autor:
Thomas Olsen, Kathrine J. Vinknes, Kristýna Barvíková, Emma Stolt, Sindre Lee-Ødegård, Hannibal Troensegaard, Hanna Johannessen, Amany Elshorbagy, Jitka Sokolová, Jakub Krijt, Michaela Křížková, Tamás Ditrói, Péter Nagy, Bente Øvrebø, Helga Refsum, Magne Thoresen, Kjetil Retterstøl, Viktor Kožich
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103192- (2024)
Background: In animals, dietary sulfur amino acid restriction (SAAR) improves metabolic health, possibly mediated by altering sulfur amino acid metabolism and enhanced anti-obesogenic processes in adipose tissue. Aim: To assess the effects of SAAR ov
Externí odkaz:
https://doaj.org/article/25c59b32605a4c42bd104f1491f8959c
Autor:
Viktor Kožich, Bernd C Schwahn, Jitka Sokolová, Michaela Křížková, Tamas Ditroi, Jakub Krijt, Youssef Khalil, Tomáš Křížek, Tereza Vaculíková-Fantlová, Blanka Stibůrková, Philippa Mills, Peter Clayton, Kristýna Barvíková, Holger Blessing, Jolanta Sykut-Cegielska, Carlo Dionisi-Vici, Serena Gasperini, Ángeles García-Cazorla, Tobias B Haack, Tomáš Honzík, Pavel Ješina, Alice Kuster, Lucia Laugwitz, Diego Martinelli, Francesco Porta, René Santer, Guenter Schwarz, Peter Nagy
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102517- (2022)
Regulation of H2S homeostasis in humans is poorly understood. Therefore, we assessed the importance of individual enzymes in synthesis and catabolism of H2S by studying patients with respective genetic defects. We analyzed sulfur compounds (including
Externí odkaz:
https://doaj.org/article/c104284c656d4baba6f0fc3dc95350b4
Autor:
Samuel, Stanovský, Josef, Bártl, Kristýna, Barvíková, Petr, Chrastina, Jakub, Krijt, Jitka, Sokolová, Klára, Berková, Zbyněk, Straňák, Katarína, Tichá, Jan, Janota, Mária, Eliášová, Richard, Plavka, Jiří, Zach, Viktor, Kožich, Tomáš, Honzík
Publikováno v:
Czecho-Slovak Pediatrics / Česko-Slovenská Pediatrie; 2024, Vol. 79 Issue 3, p145-149, 5p
Autor:
Aixa Gonzalez, Geoffrey Hughes Smith, Michael J. Gambello, Jitka Sokolová, Viktor Kožich, Hong Li
Publikováno v:
American Journal of Medical Genetics Part A. 191:130-134
Elevated total plasma homocysteine (hyperhomocysteinemia) is a marker of cardiovascular, thrombotic, and neuropsychological disease. It has multiple causes, including the common nutritional vitamin B12 or folate deficiency. However, some rare but tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ad536eef78cd627bc5ec003072c7b1
https://doi.org/10.1002/ajmg.a.63001
https://doi.org/10.1002/ajmg.a.63001
Autor:
Sailendra N. Nichenametla, Dwight A. L. Mattocks, Diana Cooke, Vishal Midya, Virginia L. Malloy, Wilfredo Mansilla, Bente Øvrebø, Cheryl Turner, Nasser E. Bastani, Jitka Sokolová, Markéta Pavlíková, John P. Richie, Anna K. Shoveller, Helga Refsum, Thomas Olsen, Kathrine J. Vinknes, Viktor Kožich, Gene P. Ables
Publikováno v:
Aging Cell. 21
SummaryDecreasing dietary intake of methionine exerts robust anti-adiposity effects in rodents but modest effects in humans. Since cysteine can be synthesized from methionine, animal diets are formulated by decreasing methionine and eliminating cyste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edeeca84f3bd1c0853b2baa779003c10
https://doi.org/10.1111/acel.13739
https://doi.org/10.1111/acel.13739
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97646 (2014)
Uric acid is the end product of purine metabolism in humans, and increased serum uric acid concentrations lead to gout. The objective of the current study was to identify factors that are independently associated with serum uric acid concentrations i
Externí odkaz:
https://doaj.org/article/0ec39de737654739bbcf52da2096423d
Autor:
Jitka Sokolová, Viktor Kožich, Jakub Krijt, Tamás Ditrói, Péter Nagy, Michaela Křížková, Pavel Ješina
Publikováno v:
British Journal of Pharmacology. 176:594-606
Background and purpose Homocystinurias are rare genetic defects characterized by altered fluxes of sulfur compounds including homocysteine and cysteine. We explored whether the severely perturbed sulfur amino acid metabolism in patients with homocyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee5574e8b459247c097eaadb799fc96
https://doi.org/10.1111/bph.14523
https://doi.org/10.1111/bph.14523
Autor:
Jitka Sokolová, Roman Vozdek, Viktor Kožich, Jakub Krijt, Petra Melenovská, Tomas Majtan, Jan P. Kraus, Pavel Ješina
Publikováno v:
Biochimie. 126:14-20
Two enzymes in the transsulfuration pathway of homocysteine -cystathionine beta-synthase (CBS) and gamma-cystathionase (CTH)-use cysteine and/or homocysteine to produce the important signaling molecule hydrogen sulfide (H2S) and simultaneously the th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560578e2be9a8b1e32d3a596b2482066
https://doi.org/10.1016/j.biochi.2016.01.001
https://doi.org/10.1016/j.biochi.2016.01.001
Publikováno v:
Urolithiasis. 43:441-445
Renal hypouricemia is a rare heterogeneous inherited disorder characterized by impaired tubular uric acid transport with severe complications, such as acute kidney injury. Type 1 and 2 are caused by loss-of-function mutations in the SLC22A12 and SLC2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a2b3c75a43e3745259580ab9ac3dcf
https://doi.org/10.1007/s00240-015-0790-4
https://doi.org/10.1007/s00240-015-0790-4
Autor:
Michele Frapolli, D. Sean Froese, Terttu Suormala, Brian Fowler, Till Rummel, Hans-Georg Koch, Alexandra Schäfer, Hana Vlaskova, Cecilia Giunta, Dorothea M. Heuberger, Matthias R. Baumgartner, Viktor Kožich, Céline Bürer, Patricie Burda, Jitka Sokolová
Publikováno v:
Human mutation
5,10-Methylenetetrahydrofolate reductase (MTHFR) deficiency is the most common inherited disorder of folate metabolism and causes severe hyperhomocysteinaemia. To better understand the relationship between mutation and function, we performed molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1661d494fd89513c703730bbfe2e613