Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jitesh K. Pillai"'
Autor:
Ishani Mondal, Mahanandeeshwar Gattu, Amitava Bhattacharyya, Pawan Goyal, Sudeshna Sarkar, Sukannya Purkayastha, Jitesh K. Pillai
Entity linking (or Normalization) is an essential task in text mining that maps the entity mentions in the medical text to standard entities in a given Knowledge Base (KB). This task is of great importance in the medical domain. It can also be used f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1668bce2a672baac1253e2191582ccb8
Publikováno v:
BIBE
Identification of potential Drug-Drug Interactions (DDI) for newly developed drugs is essential in public healthcare. Computational methods of DDI prediction rely on known interactions to learn possible interaction between drug pairs whose interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63da00682c2d0ea411efbfbc4d3b770
https://doi.org/10.1109/bibe.2019.00104
https://doi.org/10.1109/bibe.2019.00104
Autor:
Carlos Solano, Markus J. Tamás, Jianbo Yang, Timothy L. Stemmler, Nallani Vijay Kumar, Jitesh K. Pillai, Abhay Kumar, Barry P. Rosen, Swati Rawat, Morten Grøtli
Publikováno v:
Molecular and Cellular Biology. 36:913-922
The AP-1-like transcription factor Yap8 is critical for arsenic tolerance in the yeast Saccharomyces cerevisiae. However, the mechanism by which Yap8 senses the presence of arsenic and activates transcription of detoxification genes is unknown. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d243d1986c7cdbd3e0c47381fcf78669
https://doi.org/10.1128/mcb.00842-15
https://doi.org/10.1128/mcb.00842-15
Publikováno v:
Chemical Research in Toxicology
A synthetic gene encoding human As(III) S-adenosylmethionine (SAM) methyltransferase (hAS3MT) was expressed, and the purified enzyme was characterized. The synthetic enzyme is considerably more active than a cDNA-expressed enzyme using endogenous red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f589ebd2fec0904195b270a1326cf1ed
http://europepmc.org/articles/PMC4237493
http://europepmc.org/articles/PMC4237493
Publikováno v:
Analytical biochemistry. 480
Arsenic is a naturally existing toxin and carcinogen. As(III) S-adenosylmethionine methyltransferases (AS3MT in mammals and ArsM in microbes) methylate As(III) three times in consecutive steps and play a central role in arsenic metabolism from bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8c9f179fa12bba6c3e2e1f3e552a0d
https://pubmed.ncbi.nlm.nih.gov/25866076
https://pubmed.ncbi.nlm.nih.gov/25866076
Publikováno v:
Chemical research in toxicology. 27(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e552fc3f22098a935689ad0ef8a2762
https://pubmed.ncbi.nlm.nih.gov/25383631
https://pubmed.ncbi.nlm.nih.gov/25383631
The ArsA ATPase is the catalytic subunit of the ArsAB As(III) efflux pump. It receives trivalent As(III) from the intracellular metallochaperone ArsD. The interaction of ArsA and ArsD allows for resistance to As(III) at environmental concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6cb9d93aa82b7a0801d2c2b1df1e8e
https://europepmc.org/articles/PMC4224984/
https://europepmc.org/articles/PMC4224984/