Výsledky vyhledávání - "Jitendra Vishwakarma"

Arsenic Induces GSK3β-Dependent p-Tau, Neuronal Apoptosis, and Cognitive Impairment via an Interdependent Hippocampal ERα and IL-1/IL-1R1 Mechanism in Female Rats

Autor: Keerti Gupta, Jitendra Vishwakarma, Asmita Garg, Rukmani Pandey, Veena Jain, Raksha Gupta, Uttara Das, Somendu Roy, Sanghamitra Bandyopadhyay

Publikováno v: Toxicological Sciences. 190:79-98

Arsenic is an environmental contaminant with potential neurotoxicity. We previously reported that arsenic promoted hippocampal neuronal apoptosis, inducing cognitive loss. Here, we correlated it with tau pathology. We observed that environmentally re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6731342e7b09b6538240851e45153ef0
https://doi.org/10.1093/toxsci/kfac087

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Hypothyroidism induces motor deficit via altered cerebellar HB-EGF/EGFR and autophagy

Autor: Jitendra Vishwakarma, Keerti Gupta, Juhi Mishra, Asmita Garg, Rafat Malik, Amit Kashyap, Manoj Shukla, Dhirendra Singh, Sanghamitra Bandyopadhyay

Publikováno v: Journal of Endocrinology. 257

Thyroid hormones (TH) are vital for brain functions, while TH deficiency, i.e. hypothyroidism, induces neurological impairment in children and adults. Cerebellar neuronal apoptosis and motor deficits are crucial events in hypothyroidism; however, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c47c0a30ffc821f91862ba176ef26d5e
https://doi.org/10.1530/joe-22-0338

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Hypothyroidism Induces Interleukin-1-Dependent Autophagy Mechanism as a Key Mediator of Hippocampal Neuronal Apoptosis and Cognitive Decline in Postnatal Rats

Autor: Jitendra Vishwakarma, Rukmani Pandey, Juhi Mishra, Shailendra Kumar Maurya, Manoj Kumar Shukla, Asmita Garg, Sanghamitra Bandyopadhyay, Naibedya Chattopadhyay, Keerti Gupta, Rafat Malik

Publikováno v: Molecular Neurobiology. 58:1196-1211

Thyroid hormone (TH) is essential for brain development, and hypothyroidism induces cognitive deficits in children and young adults. However, the participating mechanisms remain less explored. Here, we examined the molecular mechanism, hypothesizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c103c318a422be661bf42a65555ddd61
https://doi.org/10.1007/s12035-020-02178-9

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Hypothyroidism Induces Interleukin-1-Dependent Autophagy Mechanism as a Key Mediator of Hippocampal Neuronal Apoptosis and Cognitive Decline in Postnatal Rats

Autor: Juhi, Mishra, Jitendra, Vishwakarma, Rafat, Malik, Keerti, Gupta, Rukmani, Pandey, Shailendra Kumar, Maurya, Asmita, Garg, Manoj, Shukla, Naibedya, Chattopadhyay, Sanghamitra, Bandyopadhyay

Publikováno v: Molecular neurobiology. 58(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d3510289112b6077cfcbf9941210680
https://pubmed.ncbi.nlm.nih.gov/33106949

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Rosiglitazone up-regulates glial fibrillary acidic protein via HB-EGF secreted from astrocytes and neurons through PPARγ pathway and reduces apoptosis in high-fat diet-fed mice

Autor: Juhi Mishra, Keerti Gupta, Jitendra Vishwakarma, Sanghamitra Bandyopadhyay, Rajesh Kushwaha, Naibedya Chattopadhyay, Mohan Kamthan, Jiaur R. Gayen, Anand P. Gupta

Publikováno v: Journal of neurochemistry. 149(5)

The anti-diabetic drug and peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, rosiglitazone, alters astrocyte activation; however, its mechanism remains less-known. We hypothesized participation of epidermal growth factor receptor (EG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e971f8e8eb0184e5fa7b317e0f646ac2
https://pubmed.ncbi.nlm.nih.gov/30311190

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