Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Jitendra Kumar Saxena"'
Autor:
Rajendra K Baharia, Rati Tandon, Tanuj Sharma, Manish K Suthar, Sanchita Das, Mohammad Imran Siddiqi, Jitendra Kumar Saxena, Shyam Sundar, Anuradha Dube
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 4, p e0003742 (2015)
[This corrects the article DOI: 10.1371/journal.pntd.0003557.].
Externí odkaz:
https://doaj.org/article/f3d2b4c02ef04caf80babb329d2588d8
Autor:
Rajendra K Baharia, Rati Tandon, Tanuj Sharma, Manish K Suthar, Sanchita Das, Mohammad Imran Siddiqi, Jitendra Kumar Saxena, Shaym Sundar, Anuradha Dube
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 3, p e0003557 (2015)
BACKGROUND: The development of a vaccine conferring long-lasting immunity remains a challenge against visceral leishmaniasis (VL). Immunoproteomic characterization of Leishmania donovani proteins led to the identification of a novel protein NAD+-depe
Externí odkaz:
https://doaj.org/article/f632526349984a9391a36ce6a5687ed6
Autor:
Sunita Yadav, Smita Gupta, Chandrabose Selvaraj, Pawan Kumar Doharey, Anita Verma, Sanjeev Kumar Singh, Jitendra Kumar Saxena
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106413 (2014)
Filarial parasites modulate effective immune response of their host by releasing a variety of immunomodulatory molecules, which help in the long persistence of the parasite within the host. The present study was aimed to characterize an immunomodulat
Externí odkaz:
https://doaj.org/article/a519234b3f724d9d94d136fd8004189f
Autor:
Meenakshi Kaushik, Sugeerappa L. Hoti, Jitendra Kumar Saxena, Rajesh Joshi, Ishwar Singh, Sharada Metgud, Harsha V. Hegde
Purpose: Globally, 859 million people in 50 countries are threatened by lymphatic filariasis. Due to its severity, the available drugs are mainly used for microfilaricidal and do not kill efficiently the adult parasites, which continue to produce mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b033393e805e73aaabc538b113fb873
https://doi.org/10.21203/rs.3.rs-2545927/v1
https://doi.org/10.21203/rs.3.rs-2545927/v1
Autor:
Sunita Yadav, Smita Gupta, Mohd Saeed, Huma Mustafa, Jitendra Kumar Saxena, Puvvada Kalpana Murthy
Publikováno v:
Acta Parasitologica. 67:784-793
We identified calreticulin in human filaria Brugia malayi (BmCRT) that shares 97% homology with Wuchereria bancrofti calreticulin (WbCRT), but only 56% with human calreticulin. We found that BmCRT binds C1q and prevents complement-mediated parasite d
Autor:
Pankaj Sharma, Laxmi Ganga, Jitendra Kumar Saxena, Mrigank Srivastava, Aditi Sharma, Sunita Yadav
Publikováno v:
ACS Infectious Diseases. 7:790-799
Lymphatic filariasis causes permanent and long-term disability worldwide. Lack of potent adulticidal drugs, the emergence of drug resistance, and the nonavailability of effective vaccines are the major drawbacks toward LF elimination. However, immuno
Publikováno v:
Protein Expression and Purification. 159:1-9
Arginase catalyzes the first committed step in the biosynthesis of polyamines that enable cell growth and hence potential drug target for the treatment of leishmaniasis. The arginase from Leishmania donovani (LdARG) was cloned, overexpressed and char
Autor:
Sunita, Yadav, Pankaj, Sharma, Aditi, Sharma, Laxmi, Ganga, Jitendra Kumar, Saxena, Mrigank, Srivastava
Publikováno v:
ACS infectious diseases. 7(4)
Lymphatic filariasis causes permanent and long-term disability worldwide. Lack of potent adulticidal drugs, the emergence of drug resistance, and the nonavailability of effective vaccines are the major drawbacks toward LF elimination. However, immuno
Autor:
Mrinal Ranjan Srivastava, Sharique Ahmad, Jitendra Kumar Saxena, Farzana Mahdi, Vishnu Kumar, Raj Kumar Singh
Publikováno v:
ERA'S JOURNAL OF MEDICAL RESEARCH. :30-37
Autor:
Sunita Yadav, Smita Gupta, Jitendra Kumar Saxena, Venkatesan Suryanarayanan, Sanjeev Kumar Singh
Publikováno v:
International Journal of Biological Macromolecules. 98:357-365
The present work deals with investigating the role of ionic interactions in the native conformation of BmGK by altering pH and salt concentration as well as by disruption of inter-subunit region. The study on structural and functional properties of B