Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jitender Kumar Bhardwaj"'
Autor:
Kiran Siwach, Amit Kumar, Harish Panchal, Rajiv Kumar, Jitender Kumar Bhardwaj, Andrea Angeli, Claudiu T. Supuran, Pawan K. Sharma
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1454-1463 (2022)
In search of selective carbonic anhydrase (CA) IX inhibitors endowed with apoptotic inducing properties, we designed and synthesised two subsets of 4- and 3-(5-aryl-(4-phenylsulphonyl)-1H-1,2,3-triazol-1-yl)benzenesulphonamides. All compounds were as
Externí odkaz:
https://doaj.org/article/19eccdca83fb45188fb0710d2c1acedd
Autor:
Sunita Khatkar, Santosh Kumar Dubey, Priyanka Saraf, Jitender Kumar Bhardwaj, Satish Kumar, V. Kumar, Gaje Singh, Shayoraj
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100481- (2022)
Ruthenium (Ru) Dimethylsulphoxide complexes have appeared as a prominent compound among the potential metal-based drug for the cure of cancer. Cancer is marked with the uncontrolled proliferative activity that can be treated with apoptosis inducers.
Externí odkaz:
https://doaj.org/article/5324026bb39c4bf8a7bde97a4126acb4
Publikováno v:
Toxicology International. :105-115
In the present investigation, the toxicity of imidacloprid was tested on the embryos (fertilized eggs) and hatchlings of Cyprinus carpio in terms of mortality (%), hatching success (%) and abnormal/malformed hatchling along with their growth performa
Publikováno v:
Ultrastructural Pathology. 45:407-413
The agricultural pesticide poisoning is currently the most thrust area of human health concern. Pesticide-induced cytotoxicity and the corresponding reproductive toxicity in today's scenario is not a concealed reality that has to be considered for th
Publikováno v:
Journal of Cellular Physiology. 237:1157-1170
The reproductive life span of the organism mainly depends on follicular development that maintains the primordial follicle pool in the cohort of follicles within the ovary. The total count of primordial follicles decreases with age due to ovulation a
Autor:
Lalit Vats, Kiran Siwach, Andrea Angeli, Prerna Bikal, Jitender Kumar Bhardwaj, Claudiu T. Supuran, Pawan K. Sharma
Publikováno v:
Archiv der PharmazieREFERENCES.
Inhibition of human carbonic anhydrase (hCA) isoform IX with concurrent induction of apoptosis is a promising approach for targeting cancer in humans. Prompted by the scope, novel benzenesulfonamides containing the 1,2,3-triazolylthiazolotriazole tai
Publikováno v:
Environmental and Molecular Mutagenesis. 62:374-384
Cadmium (Cd), anenvironmental toxic heavy metal, has been reported to cause testicular toxicity, which contributes to the recent decline in male fertility worldwide. Quercetin (Qcn), a major dietary antioxidant, has been shown to have protective effe
Publikováno v:
Reproductive Sciences. 28:1227-1256
The prevalence of female infertility cases has been increasing at a frightening rate, affecting approximately 48 million women across the world. However, oxidative stress has been recognized as one of the main mediators of female infertility by causi
Publikováno v:
Journal of Applied Toxicology. 41:105-117
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body. Due to a considerably long biological half-life and very low rate of excretion, accumulation of Cd in different body organs (eg, liver, kidney, and testes) over
Autor:
Monika Ola, Madhulika Bhagat, Jitender Kumar Bhardwaj, Prabodh Chander Sharma, Archana Sharma, Vijay Kumar Thakur, Diksha Sharma, Ramesh K. Goyal
Publikováno v:
Seminars in cancer biology. 86(Pt 3)
It is a major concern to treat cancer successfully, due to the distinctive pathophysiology of cancer cells and the gradual manifestation of resistance. Specific action, adverse effects and development of resistance has prompted the urgent requirement