Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jishnu K.S. Krishnan"'
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141ce3ea526168cf1e23195f9bd37f7a
https://doi.org/10.1096/fasebj.2019.33.1_supplement.868.34
https://doi.org/10.1096/fasebj.2019.33.1_supplement.868.34
Autor:
Jishnu K.S. Krishnan, Kyle Anderson, Moriah Hunstiger, Benjamin Boswell, Scott Ryan Oliver, Jace Rogers, Matthew T. Andrews
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240a0eafa3d08525ad11b78c60e08a82
https://doi.org/10.1096/fasebj.2019.33.1_supplement.701.13
https://doi.org/10.1096/fasebj.2019.33.1_supplement.701.13
Autor:
Moriah Hunstiger, Kelly L. Drew, S. Ryan Oliver, Sarah A Rice, Jishnu K.S. Krishnan, Monica L Mikes
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77ef72e823df851cf29a37f8ae2bac9
https://doi.org/10.1096/fasebj.2020.34.s1.09342
https://doi.org/10.1096/fasebj.2020.34.s1.09342
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f96908e0022261e427632dbc0669bf98
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb231
https://doi.org/10.1096/fasebj.2018.32.1_supplement.lb231
Autor:
Jishnu K.S. Krishnan, Peethambaran Arun, John R. Moffett, Abhilash P. Appu, Taiza H. Figueiredo, Aryan M.A. Namboodiri, Narayanan Puthillathu, Thomas P. Flagg, Maria F. M. Braga
Publikováno v:
Neurotoxicology. 63
Organophosphate chemical threat agents (OP-CTA) exert toxic effects through cholinergic over-activation. However, after the initial cholinergic phase, the pathophysiology shifts to a non-cholinergic phase which leads to prolonged status epilepticus (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53d31bd9e35988a9c05640321216f3e
https://pubmed.ncbi.nlm.nih.gov/28939237
https://pubmed.ncbi.nlm.nih.gov/28939237
Autor:
Sean Moran, Peethambaran Arun, Aryan M.A. Namboodiri, John R. Moffett, Abhilash P. Appu, Vikram Nambiar, Jishnu K.S. Krishnan, Narayanan Puthillathu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Canavan disease is caused by mutations in the gene encoding aspartoacylase (ASPA), a deacetylase that catabolizes N-acetylaspartate (NAA). The precise involvement of elevated NAA in the pathogenesis of Canavan disease is an ongoing debate. In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ae04c308efb7e69c956a51273b3010
http://journal.frontiersin.org/article/10.3389/fnmol.2017.00161/full
http://journal.frontiersin.org/article/10.3389/fnmol.2017.00161/full
Autor:
Narayanan Puthillathu, John R. Moffett, Abhilash P. Appu, Aryan M.A. Namboodiri, Bhadra Chembukave, Jishnu K.S. Krishnan, Peethambaran Arun, Nivetha Vijayakumar
Publikováno v:
Journal of neuroscience methods. 286
Background The intranasal route of administration has proven to be an effective method for bypassing the blood brain barrier and avoiding first pass hepatic metabolism when targeting drugs to the brain. Most small molecules gain rapid access to CNS p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d17dbbb4f2e674524ce1dc87dd47781
https://pubmed.ncbi.nlm.nih.gov/28499841
https://pubmed.ncbi.nlm.nih.gov/28499841
Autor:
Taiza H. Figueiredo, James P. Apland, Maria F. M. Braga, Volodymyr I. Pidoplichko, Steven L. Miller, Jishnu K.S. Krishnan, Vassiliki Aroniadou-Anderjaska
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 360(1)
Exposure to organophosphorus toxins induces seizures that progress to status epilepticus (SE), which can cause brain damage or death. Seizures are generated by hyperstimulation of muscarinic receptors, subsequent to inhibition of acetylcholinesterase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789cf853cbdb2f6ec4ab1eb815dce85e
https://pubmed.ncbi.nlm.nih.gov/27799295
https://pubmed.ncbi.nlm.nih.gov/27799295
Autor:
Aryan M.A. Namboodiri, Maria F. M. Braga, Natalia Farkas, William H. Frey, Nivetha Vijayakumar, Sudikshya Baskota, John R. Moffett, Taiza H. Figueiredo, John A. Dagata, Abhilash P. Appu, Jishnu K.S. Krishnan, Peethambaran Arun, Cara H. Olsen
Intranasal delivery is an emerging method for bypassing the blood brain barrier (BBB) and targeting therapeutics to the CNS. Oximes are used to counteract the effects of organophosphate poisoning, but they do not readily cross the BBB. Therefore, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df163a536d113b0eeea35212fc903075
https://europepmc.org/articles/PMC4808345/
https://europepmc.org/articles/PMC4808345/
Autor:
John R. Moffett, Abhilash P. Appu, Jishnu K.S. Krishnan, Peethambaran Arun, Aryan M.A. Namboodiri
Publikováno v:
Journal of neuroscience methods. 259
Background The blood brain barrier (BBB) is critical for maintaining central nervous system (CNS) homeostasis by restricting entry of potentially toxic substances. However, the BBB is a major obstacle in the treatment of neurotoxicity and neurologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15bbfb64e18c8a44daf070d67033dc3
https://pubmed.ncbi.nlm.nih.gov/26688469
https://pubmed.ncbi.nlm.nih.gov/26688469