Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Jiro Kikuchi"'
Autor:
Jiro Kikuchi, Mitsuo Hori, Naoki Osada, Sae Matsuoka, Atsushi Suzuki, Satoshi Kakugawa, Hiroshi Yasui, Takeshi Harada, Hirofumi Tenshin, Masahiro Abe, Hideki Nakasone, Yusuke Furukawa
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/e14a95c44b6d4444a7baef0a978500e9
Autor:
Naoki Osada, Jiro Kikuchi, Hidekatsu Iha, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Yusuke Furukawa
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 8, Pp n/a-n/a (2023)
Abstract Background The immunomodulatory drug lenalidomide, which is now widely used for the treatment of multiple myeloma (MM), exerts pharmacological action through the ubiquitin‐dependent degradation of IKZF1 and subsequent down‐regulation of
Externí odkaz:
https://doaj.org/article/0a3208aa7bc9414d92ad8a167dd711c6
Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system.
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0261699 (2022)
We report expression and purification of a FLT3 protein with ITD mutation (FLT3-ITD) with a steady tyrosine kinase activity using a silkworm-baculovirus system, and its application as a fast screening system of tyrosine kinase inhibitors. The FLT3-IT
Externí odkaz:
https://doaj.org/article/ef4d0ae41f084aeeb6ee51e4c4380495
Autor:
Naoki Osada, Jiro Kikuchi, Daisuke Koyama, Yoshiaki Kuroda, Hiroshi Yasui, Joel D. Leverson, Yusuke Furukawa
Publikováno v:
Haematologica, Vol 106, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/4ef063f73f424606b2a6a9d98867c450
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Externí odkaz:
https://doaj.org/article/18e3d3d7b6314dbbbc17b62a0a5a91c0
Autor:
Kazuya Takahashi, Takeshi Inukai, Toshihiko Imamura, Mio Yano, Chihiro Tomoyasu, David M Lucas, Atsushi Nemoto, Hiroki Sato, Meixian Huang, Masako Abe, Keiko Kagami, Tamao Shinohara, Atsushi Watanabe, Shinpei Somazu, Hiroko Oshiro, Koshi Akahane, Kumiko Goi, Jiro Kikuchi, Yusuke Furukawa, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto, Kanji Sugita
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188680 (2017)
Prognosis of childhood acute lymphoblastic leukemia (ALL) has been dramatically improved. However, prognosis of the cases refractory to primary therapy is still poor. Recent phase 2 study on the efficacy of combination chemotherapy with bortezomib (B
Externí odkaz:
https://doaj.org/article/60b8cd64dce84a0c8627f02db4c51794
Autor:
Nobuya Hiraoka, Jiro Kikuchi, Takahiro Yamauchi, Daisuke Koyama, Taeko Wada, Mitsuyo Uesawa, Miyuki Akutsu, Shigehisa Mori, Yuichi Nakamura, Takanori Ueda, Yasuhiko Kano, Yusuke Furukawa
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90675 (2014)
Bendamustine has shown considerable clinical activity against indolent lymphoid malignancies as a single agent or in combination with rituximab, but combination with additional anti-cancer drugs may be required for refractory and/or relapsed cases as
Externí odkaz:
https://doaj.org/article/86532434e6ac4ca184c34d22daf3e22a
Autor:
Jiro Kikuchi, Naoya Shibayama, Satoshi Yamada, Taeko Wada, Masaharu Nobuyoshi, Tohru Izumi, Miyuki Akutsu, Yasuhiko Kano, Kanako Sugiyama, Mio Ohki, Sam-Yong Park, Yusuke Furukawa
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60649 (2013)
The proteasome is a proteolytic machinery that executes the degradation of polyubiquitinated proteins to maintain cellular homeostasis. Proteasome inhibition is a unique and effective way to kill cancer cells because they are sensitive to proteotoxic
Externí odkaz:
https://doaj.org/article/f4d1bbfc9fca4b3085df27986acf46d8
Autor:
Jiro Kikuchi, Nobuyuki Kodama, Masataka Takeshita, Sho Ikeda, Takahiro Kobayashi, Yoshiaki Kuroda, Michihiro Uchiyama, Naoki Osada, Bjarne Bogen, Hiroshi Yasui, Naoto Takahashi, Akiyoshi Miwa, Yusuke Furukawa
Publikováno v:
Blood Advances. 7:508-524
Extramedullary disease (EMD) is known to be associated with chemoresistance and poor prognosis in multiple myeloma (MM); however, the mechanisms of its development are not fully understood. Elucidating the mechanism of EMD development and its therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e410fda829e678290a13c83ddf2125f9
https://doi.org/10.1182/bloodadvances.2022007291
https://doi.org/10.1182/bloodadvances.2022007291
Autor:
Nakanobu Hayashi, Chikako Abe, Jiro Kikuchi, Momoko Hayashi, Sakura Hayashi, Masahiro Ueda, Koyu Suzuki, Masahiko Sugitani, Hiroaki Taniguchi, Toru Wake, Yusuke Furukawa
The development of mRNA vaccines and oral drugs against SARS-CoV-2 has been useful in protecting against Covid-19 infection. Since then, however, many variants of delta and omicron strains with enhanced infectivity and immune escape capacity have eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0bb0c474b679595c45cb1270adef37c
https://doi.org/10.21203/rs.3.rs-2609957/v2
https://doi.org/10.21203/rs.3.rs-2609957/v2
