Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Jirkof P"'
Autor:
Anna Munk, Vanessa Philippi, Verena Buchecker, Marion Bankstahl, Aylina Glasenapp, Andreas Blutke, Effrosyni Michelakaki, Steven Roger Talbot, Jörg Huwyler, Paulin Jirkof, Marcin Kopaczka, Dorit Merhof, Rupert Palme, Heidrun Potschka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract While neurosurgical interventions are frequently used in laboratory mice, refinement efforts to optimize analgesic management based on multimodal approaches appear to be rather limited. Therefore, we compared the efficacy and tolerability of
Externí odkaz:
https://doaj.org/article/2e35bbed975645f2aa6e47c7be571254
Autor:
Angelique Wolter, Christian H. Bucher, Sebastian Kurmies, Viktoria Schreiner, Frank Konietschke, Katharina Hohlbaum, Robert Klopfleisch, Max Löhning, Christa Thöne-Reineke, Frank Buttgereit, Jörg Huwyler, Paulin Jirkof, Anna E. Rapp, Annemarie Lang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Adequate pain management is essential for ethical and scientific reasons in animal experiments and should completely cover the period of expected pain without the need for frequent re-application. However, current depot formulations of Bupre
Externí odkaz:
https://doaj.org/article/a3a6e5e452f34a039c52216254fc8390
Akademický článek
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Autor:
Hannah King, Maria Reiber, Vanessa Philippi, Helen Stirling, Katharina Aulehner, Marion Bankstahl, André Bleich, Verena Buchecker, Aylina Glasenapp, Paulin Jirkof, Nina Miljanovic, Katharina Schönhoff, Lara von Schumann, Cathalijn Leenaars, Heidrun Potschka
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Experimental craniotomies are a common surgical procedure in neuroscience. Because inadequate analgesia appears to be a problem in animal-based research, we conducted this review and collected information on management of craniotomy-associated pain i
Externí odkaz:
https://doaj.org/article/801a5678ce2f410fa2eae9361acd21f2
Autor:
Steven R. Talbot, Birgitta Struve, Laura Wassermann, Miriam Heider, Nora Weegh, Tilo Knape, Martine C. J. Hofmann, Andreas von Knethen, Paulin Jirkof, Christine Häger, André Bleich
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Good science in translational research requires good animal welfare according to the principles of 3Rs. In many countries, determining animal welfare is a mandatory legal requirement, implying a categorization of animal suffering, traditionally domin
Externí odkaz:
https://doaj.org/article/a4fc9e7b330b43b6bb9893ea57bb909b
Autor:
Katharina Aulehner, Cathalijn Leenaars, Verena Buchecker, Helen Stirling, Katharina Schönhoff, Hannah King, Christine Häger, Ines Koska, Paulin Jirkof, André Bleich, Marion Bankstahl, Heidrun Potschka
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Several studies suggested an informative value of behavioral and grimace scale parameters for the detection of pain. However, the robustness and reliability of the parameters as well as the current extent of implementation are still largely unknown.
Externí odkaz:
https://doaj.org/article/23030b4e1e6c4f649c5557650a915b66
Lidocaine and bupivacaine as part of multimodal pain management in a C57BL/6J laparotomy mouse model
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract While the use of local anesthesia as part of multimodal pain management is common practice in human and veterinarian surgery, these drugs are not applied routinely in rodent surgery. Several recommendations on the use of local anesthesia exi
Externí odkaz:
https://doaj.org/article/4b9c9702432e4c7a948890367209718d
Autor:
Anke Tappe-Theodor, Claudia Pitzer, Lars Lewejohann, Paulin Jirkof, Katja Siegeler, Astra Segelcke, Natascha Drude, Bruno Pradier, Esther Pogatzki-Zahn, Britta Hollinderbäumer, Daniel Segelcke
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The prospective severity assessment in animal experiments in the categories' non-recovery, mild, moderate, and severe is part of each approval process and serves to estimate the harm/benefit. Harms are essential for evaluating ethical justifiability,
Externí odkaz:
https://doaj.org/article/6710302be71640a7b86a5a4dfea7f037
Analysis of Pain and Analgesia Protocols in Acute Cerulein-Induced Pancreatitis in Male C57BL/6 Mice
Autor:
Mattea Durst, Theresia Reding Graf, Rolf Graf, Mareike Kron, Margarete Arras, Dietmar Zechner, Rupert Palme, Steven R. Talbot, Paulin Jirkof
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Pancreatitis is known to be painful in humans and companion animals. However, the extent of pain in experimental mouse models of acute pancreatitis is unknown. Consequently, the severity classification of acute pancreatitis in mice is controversially
Externí odkaz:
https://doaj.org/article/d6f4ca10b124429e90c5ca8998d56365
Akademický článek
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