Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jirina Martinkova"'
Autor:
Milan Kaska, Eduard Havel, Iva Selke-Krulichova, Petr Safranek, Jan Bezouska, Jirina Martinkova
Publikováno v:
Biomedical Papers, Vol 162, Iss 3, Pp 219-226 (2018)
Aims: Critically ill patients undergoing aggressive fluid resuscitation and treated empirically with hydrosoluble time-dependent beta-lactam antibiotics are at risk for sub-therapeutic plasma concentrations. The aim of this study was to assess the im
Externí odkaz:
https://doaj.org/article/1dbf3825358b4b0aacf4f2cb0d1ca7da
Autor:
Jirina Martinkova, Marian Hajduch, Daniel Enetoft, Ola Forsstrom-Olsson, Hana Kovarova, Suresh Jivan Gadher, Helena Kupcova Skalnikova, Marta Dziechciarkova, Andreas Hammar, Andreas Ekefjard, Rita Hrabakova, Petr Halada
Publikováno v:
Journal of Proteome Research. 10:404-415
Resistance to anti-cancer drugs is a well recognized problem and very often it is responsible for failure of the cancer treatment. In this study, the proteome alterations associated with the development of acquired resistance to cyclin-depedent kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dffe04135ebf53411947ea5d1ae8657
https://doi.org/10.1021/pr100468w
https://doi.org/10.1021/pr100468w
Autor:
Iva Selke-Krulichova, Václav Vobruba, Pavla Pokorná, Jirina Chládková, Jiri Zahora, Jirina Martinkova, Jaroslav Chládek
Publikováno v:
Clinical Therapeutics. 32:2400-2414
Aminoglycosides are bactericidal antibiotics used worldwide for the treatment of serious infections in critically ill patients, including neonates. Critically ill neonates constitute a unique challenge in dosing owing to the pathologic alterations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf97231740c48cbc6fde465a32cafd2
https://doi.org/10.1016/j.clinthera.2011.01.013
https://doi.org/10.1016/j.clinthera.2011.01.013
Autor:
Jaroslav Mokry, Frantisek Staud, Norbert Cibicek, Jolana Cermanova, Jan Österreicher, Leos Fuksa, Eva Brcakova, Stanislav Micuda, Jirina Martinkova
Publikováno v:
Journal of Gastroenterology and Hepatology. 23:e225-e230
Background and Aim: The present study was aimed to evaluate the hepatic zonation of multidrug resistance-associated protein 2 (mrp2), an important drug transporter, and its potential changes during the induction of its expression by known inducer, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35adffa6fb06750d916328f7cc12759
https://doi.org/10.1111/j.1440-1746.2007.05066.x
https://doi.org/10.1111/j.1440-1746.2007.05066.x
Autor:
Josef Chmelík, Michaela Zilvarova, Suresh Jivan Gadher, Helena Kupcova Skalnikova, Pavel Rehulka, Jirina Martinkova, Hana Kovarova
Publikováno v:
Analytical and Bioanalytical Chemistry. 389:1639-1645
We describe an optimised protocol for application of isobaric tags for relative and absolute quantitation (iTRAQ) and tandem mass spectrometry to obtain relative quantitative data from peptides derived from tryptic digestions of proteins fractionated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1db76bd62101f76f888f3cc558d88b9
https://doi.org/10.1007/s00216-007-1547-x
https://doi.org/10.1007/s00216-007-1547-x
Autor:
Leos Fuksa, Stanislav Micuda, Lucie Mundlova, Jan Österreicher, Jaroslav Mokry, Frantisek Staud, Jirina Martinkova, Jolana Cermanova, Pavla Pokorná, Eva Brcakova
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 34:296-303
SUMMARY 1 The effect of dexamethasone on hepatic and renal P-glycoprotein (P-gp) expression, localization and activity was investigated in rats after 4 days oral administration of two dose regimens (1 or 25 mg/kg per day). Simultaneous increases in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bb9ade147a82b17f9f3cb6853f5c2d6
https://doi.org/10.1111/j.1440-1681.2007.04558.x
https://doi.org/10.1111/j.1440-1681.2007.04558.x
Autor:
Hana Kovarova, Károly Vékey, Jirina Martinkova, Guenter Allmaier, Suresh Jivan Gadher, László Drahos
Publikováno v:
Expert Review of Proteomics. 7:15-17
The third Central and Eastern European Proteomic Conference was held at Hotel Benzcur, Budapest, Hungary, from the 6–9 October 2009. The meeting was the third in a series of proteomic conferences to be held in this region of Europe, with the key ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b863f2351fb937e140ebb006c036b78
https://doi.org/10.1586/epr.09.95
https://doi.org/10.1586/epr.09.95
Autor:
Jaroslav Chládek, Otakar Krs, Dasa Slizova, Šárka Studená, Marian Senkerik, Drahomira Springer, Jirina Martinkova
Publikováno v:
ResearcherID
A rat model of early sepsis induced by lipopolysaccharide (LPS) combined with interleukin-2 (IL-2) was developed. The primary aim was to assess the pharmacokinetics of gentamicin and sepsis-induced pathophysiological changes. Moreover, the effects on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a82f30a9534a29fdbe303c811eb6b3
https://pubmed.ncbi.nlm.nih.gov/23037160
https://pubmed.ncbi.nlm.nih.gov/23037160
Autor:
Hana Kovarova, Suresh Jivan Gadher, Jirina Martinkova, Karla Jarkovska, Petr Halada, Lucie Liskova, Karel Rezabek, Jiri Moos
Publikováno v:
Journal of proteome research. 9(3)
In vitro fertilization (IVF) is fraught with problems and currently proteomics approaches are being tried out to examine the microenvironment of the follicle in order to assess biological and immunological parameters that may affect its development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44613143414b876db339b8ef3beffbe8
https://pubmed.ncbi.nlm.nih.gov/20058866
https://pubmed.ncbi.nlm.nih.gov/20058866
Autor:
Zuzana Červinková, Eva Brcakova, Leos Fuksa, Petra Hirsova, Milos Hroch, Gabriela Kolouchova, Jolana Cermanova, Jirina Martinkova, Stanislav Micuda, Frantisek Staud, Jana Malakova, Otto Kucera
Publikováno v:
Pharmacological research. 61(2)
Although amiodarone (AMD) is known to produce drug–drug interactions through inhibition of transporter-mediated excretion of drugs, its impact on these mechanisms during chronic treatment has not been described yet. Therefore, the aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a3cc513a96da5391f480e1c1ccf2d3
https://pubmed.ncbi.nlm.nih.gov/19703566
https://pubmed.ncbi.nlm.nih.gov/19703566