Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Jiri Zavadil"'
Autor:
Sriram Vijayraghavan, Thomas Blouin, James McCollum, Latarsha Porcher, François Virard, Jiri Zavadil, Carol Feghali-Bostwick, Natalie Saini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Systemic sclerosis is a connective tissue disorder characterized by excessive fibrosis that primarily affects women, and can present as a multisystem pathology. Roughly 4-22% of patients with systemic sclerosis develop cancer, which drastica
Externí odkaz:
https://doaj.org/article/9922427373d4473b9e26d8079f0b5aff
Autor:
Dinesh Kumar Barupal, Mary K. Schubauer-Berigan, Michael Korenjak, Jiri Zavadil, Kathryn Z. Guyton
Publikováno v:
Environment International, Vol 156, Iss , Pp 106624- (2021)
Background: Systematic evaluation of literature data on the cancer hazards of human exposures is an essential process underlying cancer prevention strategies. The scope and volume of evidence for suspected carcinogens can range from very few to thous
Externí odkaz:
https://doaj.org/article/b282f6c920bf4492b2eedf31a0e2d25c
Autor:
Shefali Thakur, Vincent Cahais, Tereza Turkova, Tomas Zikmund, Claire Renard, Tomáš Stopka, Michael Korenjak, Jiri Zavadil
Publikováno v:
Cells, Vol 11, Iss 5, p 808 (2022)
Smarca5, an ATPase of the ISWI class of chromatin remodelers, is a key regulator of chromatin structure, cell cycle and DNA repair. Smarca5 is deregulated in leukemia and breast, lung and gastric cancers. However, its role in oncogenesis is not well
Externí odkaz:
https://doaj.org/article/a8ac3bed259a4190a1e6f7bf17570abe
Autor:
Daniele Viarisio, Karin Müller-Decker, Rosita Accardi, Alexis Robitaille, Matthias Dürst, Katrin Beer, Lars Jansen, Christa Flechtenmacher, Matthias Bozza, Richard Harbottle, Catherine Voegele, Maude Ardin, Jiri Zavadil, Sandra Caldeira, Lutz Gissmann, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006783 (2018)
Cutaneous beta human papillomavirus (HPV) types are suspected to be involved, together with ultraviolet (UV) radiation, in the development of non-melanoma skin cancer (NMSC). Studies in in vitro and in vivo experimental models have highlighted the tr
Externí odkaz:
https://doaj.org/article/7fa4403cea6f40ffa5dbfb8e53cb8dce
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179645 (2017)
MicroRNAs are considered as promising prognostic and diagnostic biomarkers of human cancer since their profiles differ between tumor types. Most of the tumor profiling studies were performed on rarely available fresh frozen (FF) samples. Alternativel
Externí odkaz:
https://doaj.org/article/db6ac7e2688b422eba983772f3668f5c
Global Reprogramming of the Cellular Translational Landscape Facilitates Cytomegalovirus Replication
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 9-17 (2014)
Unlike many viruses that suppress cellular protein synthesis, host mRNA translation and polyribosome formation are stimulated by human cytomegalovirus (HCMV). How HCMV impacts the translationally regulated cellular mRNA repertoire and its contributio
Externí odkaz:
https://doaj.org/article/8533250449ce4cd38f966a5a9c5a9da8
Autor:
Eva Hernando, Anna Pavlick, Jiri Zavadil, Judy Zhong, Sung Won Han, Laura Poliseno, Erica Friedman, Miguel F. Segura, Kathryn E. O'Reilly, Eleazar Vega-Saenz de Miera, Iman Osman
Publikováno v:
Pharmaceuticals, Vol 6, Iss 11, Pp 1429-1450 (2013)
Previous reports have demonstrated a role for hedgehog signaling in melanoma progression, prompting us to explore the therapeutic benefit of targeting this pathway in melanoma. We profiled a panel of human melanoma cell lines and control melanocytes
Externí odkaz:
https://doaj.org/article/d9f6fdcc9f12438483534027a1844c36
Autor:
David S. Park, Rose O. Tompkins, Fangyu Liu, Jie Zhang, Colin K. L. Phoon, Jiri Zavadil, Glenn I. Fishman
Publikováno v:
Biology Open, Vol 2, Iss 9, Pp 968-978 (2013)
Summary During development, the ventricular conduction system (VCS) arises from the trabecular or spongy myocardium. VCS and trabecular myocytes proliferate at a significantly slower rate than compact zone myocardial cells, establishing a transmural
Externí odkaz:
https://doaj.org/article/8ccd066739a341888535bbc82e9595af
Autor:
Sachin Jhawar, Prabhjot Singh, Daniel Torres, Francisco Ramirez-Valle, Hania Kassem, Trina Banerjee, Igor Dolgalev, Adriana Heguy, Jiri Zavadil, Jerome Lowenstein
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118703 (2015)
Chronic renal failure is characterized by progressive renal scarring and accelerated arteriosclerotic cardiovascular disease despite what is considered to be adequate hemodialysis or peritoneal dialysis. In rodents with reduced renal mass, renal scar
Externí odkaz:
https://doaj.org/article/8887cc23a89149948fd31d4123f87ac0
Autor:
Felipe Vaca-Paniagua, Rosa María Alvarez-Gomez, Hector Aquiles Maldonado-Martínez, Carlos Pérez-Plasencia, Veronica Fragoso-Ontiveros, Federico Lasa-Gonsebatt, Luis Alonso Herrera, David Cantú, Enrique Bargallo-Rocha, Alejandro Mohar, Geoffroy Durand, Nathalie Forey, Catherine Voegele, Maxime Vallée, Florence Le Calvez-Kelm, James McKay, Maude Ardin, Stéphanie Villar, Jiri Zavadil, Magali Olivier
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126762 (2015)
Triple negative breast cancer (TNBC), defined by the lack of expression of the estrogen receptor, progesterone receptor and human epidermal receptor 2, is an aggressive form of breast cancer that is more prevalent in certain populations, in particula
Externí odkaz:
https://doaj.org/article/617f7987f3844922893738eb8f8daf3f