Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jiri Novacek"'
Autor:
Elda Bauda, Benoit Gallet, Jana Moravcova, Gregory Effantin, Helena Chan, Jiri Novacek, Pierre-Henri Jouneau, Christopher D. A. Rodrigues, Guy Schoehn, Christine Moriscot, Cecile Morlot
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Bacterial spores owe their incredible resistance capacities to molecular structures that protect the cell content from external aggressions. Among the determinants of resistance are the quaternary structure of the chromosome and an extracell
Externí odkaz:
https://doaj.org/article/65c8735018a44e24869dfdb648bfbea7
Autor:
Sarah Clark, Janette B Myers, Ashleigh King, Radovan Fiala, Jiri Novacek, Grant Pearce, Jörg Heierhorst, Steve L Reichow, Elisar J Barbar
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/18e492cfab584fc69630a6263b204d40
Autor:
Jiri Novacek, Pavel Veverka, Tomas Brom, Matyas Pinkas, Ctirad Hofr, Tomáš Janovič, Martin Stojaspal
The RE1-Silencing Transcription factor (REST) is essential for neuronal differentiation. Here, we report the first 18.5-angstrom electron microscopy structure of human REST. The refined electron map suggests that REST forms a torus that can accommoda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6c97ccb64b22458d0a54f6dc81d45d
https://doi.org/10.1101/2022.10.06.511111
https://doi.org/10.1101/2022.10.06.511111
Autor:
David Zapletal, Eliska Taborska, Josef Pasulka, Radek Malik, Karel Kubicek, Martina Zanova, Christian Much, Marek Sebesta, Valeria Buccheri, Filip Horvat, Irena Jenickova, Michaela Prochazkova, Jan Prochazka, Matyas Pinkas, Jiri Novacek, Diego F. Joseph, Radislav Sedlacek, Carrie Bernecky, Dónal O’Carroll, Richard Stefl, Petr Svoboda
Publikováno v:
Zapletal, D, Taborska, E, Pasulka, J, Malik, R, Kubicek, K, Zanova, M, Much, C, Sebesta, M, Buccheri, V, Horvat, F, Jenickova, I, Prochazkova, M, Prochazka, J, Pinkas, M, Novacek, J, Joseph, D F, Sedlacek, R, Bernecky, C, O'Carroll, D, Stefl, R & Svoboda, P 2022, ' Structural and functional basis of mammalian microRNA biogenesis by Dicer ', Molecular Cell, vol. 82, no. 21, pp. 4064-4079.e13 . https://doi.org/10.1016/j.molcel.2022.10.010
MicroRNA (miRNA) and RNA interference (RNAi) pathways rely on small RNAs produced by Dicer endonucleases. Mammalian Dicer primarily supports the essential gene-regulating miRNA pathway, but how it is specifically adapted to miRNA biogenesis is unknow
Autor:
David Zapletal, Eliska Taborska, Josef Pasulka, Radek Malik, Karel Kubicek, Martina Zanova, Christian Much, Marek Sebesta, Valeria Buccheri, Filip Horvat, Irena Jenickova, Michaela Prochazkova, Jan Prochazka, Matyas Pinkas, Jiri Novacek, Diego F. Joseph, Radislav Sedlacek, Dónal O’Carroll, Richard Stefl, Petr Svoboda
Mammalian Dicer is the gatekeeper into the essential gene-regulating miRNA pathway. What is committing mammalian Dicer to the miRNA pathway remains unknown. We report that Dicer’s highly conserved DExD/H helicase domain is the key structural elemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::367d07d1ea5a3c80af87dfce0d1a622a
https://doi.org/10.1101/2022.04.13.488181
https://doi.org/10.1101/2022.04.13.488181
Autor:
Nina Kunová, Gabriela Ondrovičová, Jacob A. Bauer, Veronika Krajčovičová, Matyáš Pinkas, Barbora Stojkovičová, Henrieta Havalová, Veronika Lukáčová, Lenka Kohútová, Július Košťan, Lucia Martináková, Peter Baráth, Jiří Nováček, Sebastian Zoll, Sami Kereϊche, Eva Kutejová, Vladimír Pevala
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Phosphorylation plays a crucial role in the regulation of many fundamental cellular processes. Phosphorylation levels are increased in many cancer cells where they may promote changes in mitochondrial homeostasis. Proteomic studies on variou
Externí odkaz:
https://doaj.org/article/5368c6745a034ecba542e4c421929eab
Autor:
Michal Babiak, Katharina M. Rolfes, Ouldouz Ghashghaei, Rodolfo Lavilla, Marina Pedrola, Victor V Martin, Ricardo Zavarce, Frederick Hartung, Jiri Novacek, Francesca Seghetti, Thomas Haarmann-Stemmann
Publikováno v:
Angewandte Chemie. 133:2635-2640
The participation of reactants undergoing a polarity inversion along a multicomponent reaction allows the continuation of the transformation with productive domino processes. Thus, indole aldehydes in Groebke-Blackburn-Bienaymé reactions lead to an
Autor:
Jiri Novacek, Taras Sych, Erdinc Sezgin, Florian Weber, Birgit Plochberger, Markus Axmann, Herbert Stangl
Publikováno v:
Biochemistry
Lipid transfer from lipoprotein particles to cells is essential for lipid homeostasis. High density lipoprotein (HDL) particles are mainly captured by cell-membrane-associated scavenger receptor class B type 1 (SR-B1) from the blood stream while low
Autor:
Xabier Agirrezabala, Ekaterina Samatova, Meline Macher, Marija Liutkute, Manisankar Maiti, David Gil‐Carton, Jiri Novacek, Mikel Valle, Marina V Rodnina
Publikováno v:
The EMBO Journal
Cellular proteins begin to fold as they emerge from the ribosome. The folding landscape of nascent chains is not only shaped by their amino acid sequence but also by the interactions with the ribosome. Here, we combine biophysical methods with cryo-E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac7fd4b6df2313930ed5d83924f6ef7
https://hdl.handle.net/21.11116/0000-000A-CA95-A21.11116/0000-000A-CA98-7
https://hdl.handle.net/21.11116/0000-000A-CA95-A21.11116/0000-000A-CA98-7
Autor:
Aiste Kasiliauskaite, Karel Kubicek, Tomas Klumpler, Martina Zanova, David Zapletal, Eliska Koutna, Jiri Novacek, Richard Stefl
Publikováno v:
Nucleic acids research 50(10), 5961-5973 (2022). doi:10.1093/nar/gkac451
Nucleic acids research / Special publication 50(10), 5961 - 5973 (2022). doi:10.1093/nar/gkac451
Transcription elongation factor Spt6 associates with RNA polymerase II (Pol II) and acts as a histone chaperone, which promotes the reassembly of nu
Transcription elongation factor Spt6 associates with RNA polymerase II (Pol II) and acts as a histone chaperone, which promotes the reassembly of nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9ed38e5cc6c98e60fb529848e7c907