Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jiri Keirsse"'
Autor:
Jaitip Tipanee, Mario Di Matteo, Warut Tulalamba, Ermira Samara-Kuko, Jiri Keirsse, Jo A. Van Ginderachter, Marinee Khim Chuah, Thierry VandenDriessche
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1309-1329 (2020)
We established a semi-high-throughput in vivo screening platform using hyperactive piggyBac (hyPB) transposons (designated as PB-miR) to identify microRNAs (miRs) that inhibit hepatocellular carcinoma (HCC) development in vivo, following miR overexpr
Externí odkaz:
https://doaj.org/article/892c893b67c94af681db97ef39bae16c
Autor:
Damya Laoui, Jiri Keirsse, Yannick Morias, Eva Van Overmeire, Xenia Geeraerts, Yvon Elkrim, Mate Kiss, Evangelia Bolli, Qods Lahmar, Dorine Sichien, Jens Serneels, Charlotte L. Scott, Louis Boon, Patrick De Baetselier, Massimiliano Mazzone, Martin Guilliams, Jo A. Van Ginderachter
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
Dendritic cells are antigen-presenting cells consisting of distinct subsets originating from different lineages. Here, the authors identify the subsets of dendritic cells populating the tumour tissue in both mice and humans and find they have opposin
Externí odkaz:
https://doaj.org/article/a203b2adbb4344c7be80bcf4c68f425a
Publikováno v:
Bio-Protocol, Vol 9, Iss 1 (2019)
Inflammatory Ly6Chi monocytes can give rise to distinct mononuclear myeloid cells in the tumor microenvironment, such as monocytic myeloid-derived suppressor cells (Mo-MDSC), immature macrophages, M2-like tumor-associated macrophages (TAMs), M1-like
Externí odkaz:
https://doaj.org/article/96f82bac472c43bb8f979b768ca655e5
Autor:
Jennifer Cnops, Carl De Trez, Benoit Stijlemans, Jiri Keirsse, Florence Kauffmann, Mark Barkhuizen, Roanne Keeton, Louis Boon, Frank Brombacher, Stefan Magez
Publikováno v:
PLoS Pathogens, Vol 11, Iss 6, p e1004964 (2015)
African trypanosomes are the causative agents of Human African Trypanosomosis (HAT/Sleeping Sickness) and Animal African Trypanosomosis (AAT/Nagana). A common hallmark of African trypanosome infections is inflammation. In murine trypanosomosis, the o
Externí odkaz:
https://doaj.org/article/341592b48dc444e99d9cf83031d20148
Autor:
Benoit Stijlemans, Amanda Sparkes, Chloé Abels, Jiri Keirsse, Lea Brys, Yvon Elkrim, Patrick Baetselier, Alain Beschin, Jo Ginderachter
Publikováno v:
Bio-Protocol, Vol 5, Iss 10 (2015)
In homeostasis, the liver is critical for the metabolism of nutrients including sugars, lipids, proteins and iron, for the clearance of toxins, and to induce immune tolerance to gut-derived antigens. These functions predispose the liver to infection
Externí odkaz:
https://doaj.org/article/2d25a723fb274302aff3ebd034be7362
Publikováno v:
Bio-Protocol, Vol 4, Iss 22 (2014)
Tumors are heterogeneous microenvironments where complex interactions take place between neoplastic cells and infiltrating inflammatory cells, such as tumor-associated macrophages (TAM) and tumor-associated dendritic cells (TADC). The relevance of tu
Externí odkaz:
https://doaj.org/article/8146a82533164bb3a948cea178fd2aaa
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
Supplementary Figures 1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ac555aa6d9d63833368748b3be0a555
https://doi.org/10.1158/2326-6066.22543494
https://doi.org/10.1158/2326-6066.22543494
Autor:
Damya Laoui, Jo A. Van Ginderachter, Mohamed Lamkanfi, Andy Wullaert, Alain Beschin, Massimiliano Mazzone, Diether Lambrechts, Geert van Loo, Geert Raes, Louis Boon, Amelie Fossoul, Ayla Debraekeleer, Jan Brughmans, Maryse Schmoetten, Yvon Elkrim, Sana M. Arnouk, Pauline M.R. Bardet, Jiri Keirsse, Evangelia Bolli, Samantha Pretto, Manuel Ehling, Junbin Qian, Aleksandar Murgaski, Helena Van Damme, Els Lebegge, Pedro H.V. Saavedra, Lieselotte Vande Walle, Máté Kiss
IL1β is a central mediator of inflammation. Secretion of IL1β typically requires proteolytic maturation by the inflammasome and formation of membrane pores by gasdermin D (GSDMD). Emerging evidence suggests an important role for IL1β in promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17834bb72b19f02c483a544d32dc5d61
https://doi.org/10.1158/2326-6066.c.6550290
https://doi.org/10.1158/2326-6066.c.6550290
Autor:
Damya Laoui, Carola H. Ries, Martina Schmittnaegel, Greetje Vande Velde, Abhishek D. Garg, Sophie Janssens, Sofie Deschoemaeker, Niels Vandamme, Sabine Hoves, Louis Boon, Yvon Elkrim, Victor Bosteels, Ayla Debraekeleer, Ahmed E.I. Hamouda, Sana M. Arnouk, Jan Brughmans, Eva Hadadi, Jiri Keirsse, Isaure Vanmeerbeek, Daliya Kancheva, Helena Van Damme, Máté Kiss, Aleksandar Murgaski
Agonistic αCD40 therapy has been shown to inhibit cancer progression in only a fraction of patients. Understanding the cancer cell–intrinsic and microenvironmental determinants of αCD40 therapy response is therefore crucial to identify responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8705c56f1955289a0b4fab89b0fdd1
https://doi.org/10.1158/0008-5472.c.6514056.v1
https://doi.org/10.1158/0008-5472.c.6514056.v1
Autor:
Damya Laoui, Carola H. Ries, Martina Schmittnaegel, Greetje Vande Velde, Abhishek D. Garg, Sophie Janssens, Sofie Deschoemaeker, Niels Vandamme, Sabine Hoves, Louis Boon, Yvon Elkrim, Victor Bosteels, Ayla Debraekeleer, Ahmed E.I. Hamouda, Sana M. Arnouk, Jan Brughmans, Eva Hadadi, Jiri Keirsse, Isaure Vanmeerbeek, Daliya Kancheva, Helena Van Damme, Máté Kiss, Aleksandar Murgaski
Supplementary Figure from Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08db7c20b68f67424db03239cdfb9dc3
https://doi.org/10.1158/0008-5472.22432053
https://doi.org/10.1158/0008-5472.22432053