Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jiri Kanta"'
Autor:
Jiri Kanta
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
A characteristic feature of liver cirrhosis is the accumulation of large amounts of connective tissue with the prevailing content of type I collagen. Elastin is a minor connective tissue component in normal liver but it is actively synthesized by hep
Externí odkaz:
https://doaj.org/article/25a7a5b6bdf4405195dea21f0779e1b4
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Externí odkaz:
https://doaj.org/article/f12d1b51739d4de2b7b03a80f960b05d
Metabolism of fibronectin, the protein that plays a key role in the healing of wounds, is changed in the patients with diabetes mellitus. Fibronectin can interact with other proteins and proteoglycans and organise them to form the extracellular matri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe11c9b18ea906528251ad8b13f858f0
Autor:
Anna Zavadakova, Jiri Kanta
Publikováno v:
Vascular Medicine. 25:588-597
Fibronectin (FN) circulating in the blood and produced by cells provides the basis of the extracellular matrix (ECM) formed in healing acute wounds. The time-dependent deposition of FN by macrophages, its synthesis by fibroblasts and myofibroblasts,
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Rat liver myofibroblasts (MFB) are the key cells involved in the deposition of extracellular matrix in fibrotic liver. They were isolated by repeated passaging of non-parenchymal cell fraction and cultured in 3-dimensional (3D) collagen gel mimicking
Autor:
Vlasta Tkacova, Renata Köhlerová, Burak Tahmazoglu, Alena Jiroutová, Vladimir Velebny, Jiri Kanta, Lubos Sobotka, Rastislav Slavkovsky, Martina Rezacova
Publikováno v:
Wound Repair and Regeneration. 19:515-525
Impaired diabetic wound healing is an important current medical issue, mainly concerning patients recovering from complicated operations or patients with ulcers on their feet. The obese Zucker diabetic fatty rat, with a mutation in leptin receptors,
Autor:
Milena Hajzlerova, Lenka Majdiakova, Martina Cermakova, Ema Ruszova, Jiri Kanta, Alena Jiroutová, Rastislav Slavkovsky, Hana Radilova, Irena Hanovcova, Radka Bolehovska
Publikováno v:
Experimental and Toxicologic Pathology. 58:263-273
Hepatic stellate cells (HSC) and liver myofibroblasts (MFB) are two cell populations most likely responsible for the synthesis of most connective tissue components in fibrotic liver. They differ in their origin and location, and possibly in patterns
Publikováno v:
Acta Medica, Vol 48, Iss 3, Pp 137-144 (2005)
Hepatic stellate cells (HSC) are located in Disse spaces of normal rat liver. In their quiescent state they serve as a storage site for vitamin A. In fibrotic liver they become activated, proliferate and they undergo transdifferentiation into myofibr
Publikováno v:
Liver. 22:220-227
Background/Aims: Activated hepatic stellate cells (HSC) are regarded as the principal cells synthesizing extracellular matrix components in fibrotic liver. Elastin content is increased in cirrhotic livers, but the cellular source is not known. Contri
Autor:
Ulrich Werner, Karl-Heinz Baringhaus, Ludwig Schmidts, Michael Stapf, Jiri Kanta, Volkmar Günzler, Martin Gerl, Martin Bickel, Georg Tschank, Klaus Dr Weidmann
Publikováno v:
Hepatology. 28:404-411
Fibrosis and cirrhosis of the liver are often the result of chronic liver damage by a variety of different agents. Pathological accumulation of collagen, disruption of the lobular structure, and impaired hepatocellular function frequently lead to sys