Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Jiri, Neuzil"'
Autor:
Radek Sindelka, Ravindra Naraine, Pavel Abaffy, Daniel Zucha, Daniel Kraus, Jiri Netusil, Karel Smetana, Lukas Lacina, Berwini Beduya Endaya, Jiri Neuzil, Martin Psenicka, Mikael Kubista
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background Embryos are regeneration and wound healing masters. They rapidly close wounds and scarlessly remodel and regenerate injured tissue. Regeneration has been extensively studied in many animal models using new tools such as single-cel
Externí odkaz:
https://doaj.org/article/ec44e75ff06d4af7b54c5b332a61430b
Autor:
Anne P. M. Beerkens, Daan F. Boreel, James A. Nathan, Jiri Neuzil, Gang Cheng, Balaraman Kalyanaraman, Micael Hardy, Gosse J. Adema, Sandra Heskamp, Paul N. Span, Johan Bussink
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Background Hypoxia is a common feature of many solid tumors and causes radiotherapy and immunotherapy resistance. Pharmacological inhibition of oxidative phosphorylation (OXPHOS) has emerged as a therapeutic strategy to reduce hypoxia. Howev
Externí odkaz:
https://doaj.org/article/6158a99077a34dd2a03b9ab6923fa43f
Autor:
Jaromir Novak, Jiri Neuzil
Publikováno v:
PLoS Biology, Vol 22, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/9ab34f0c41d7452487c74498d2ab5d64
Publikováno v:
Aspects of Molecular Medicine, Vol 3, Iss , Pp 100041- (2024)
Externí odkaz:
https://doaj.org/article/0665c6e991ee4ded9a3bbf7da97d3f65
Autor:
Patries Herst, Georgia Carson, Danielle Lewthwaite, David Eccles, Alfonso Schmidt, Andrew Wilson, Carole Grasso, David O’Sullivan, Jiri Neuzil, Melanie McConnell, Michael Berridge
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundFast adaptation of glycolytic and mitochondrial energy pathways to changes in the tumour microenvironment is a hallmark of cancer. Purely glycolytic ρ0 tumour cells do not form primary tumours unless they acquire healthy mitochondria from
Externí odkaz:
https://doaj.org/article/f9a225c869ff448984e6d3f04e25c9bd
Autor:
Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova, Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova, Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K. Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini, T. M. Iverson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Complex II (CII) activity controls phenomena that require crosstalk between metabolism and signaling, including neurodegeneration, cancer metabolism, immune activation, and ischemia-reperfusion injury. CII activity can be regulated at the le
Externí odkaz:
https://doaj.org/article/a63f5096183a4241a866d4154beb8b16
Autor:
Aneta Marvanova, Petr Kasik, Barbara Elsnicova, Veronika Tibenska, František Galatik, Daniela Hornikova, Veronika Zvolska, Pavel Vebr, Petr Vodicka, Lucie Hejnova, Petr Matous, Barbara Szeiff Bacova, Matus Sykora, Jiri Novotny, Jiri Neuzil, Frantisek Kolar, Olga Novakova, Jitka M. Zurmanova
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Moderate cold acclimation (MCA) is a non-invasive intervention mitigating effects of various pathological conditions including myocardial infarction. We aim to determine the shortest cardioprotective regimen of MCA and the response of β1/2/
Externí odkaz:
https://doaj.org/article/d34e3872bd694fb2a062b611ded5301a
Autor:
Marco Tomasetti, Federica Monaco, Olga Strogovets, Luca Volpini, Matteo Valentino, Monica Amati, Jiri Neuzil, Lory Santarelli
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Objectives Malignant pleural mesothelioma (MPM) is an aggressive disease with grim prognosis due to lack of effective treatment options. Disease prediction in association with early diagnosis may both contribute to improved MPM survival. Inf
Externí odkaz:
https://doaj.org/article/743579aa895a4c80a97db2277479d4f2
Autor:
Zuzana Bielcikova, Lukas Werner, Jan Stursa, Vladimir Cerny, Ludmila Krizova, Jan Spacek, Stanislav Hlousek, Michal Vocka, Olga Bartosova, Michal Pesta, Katarina Kolostova, Petr Klezl, Vladimir Bobek, Jaroslav Truksa, Sona Stemberkova-Hubackova, Lubos Petruzelka, Pavel Michalek, Jiri Neuzil
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Mitochondrially targeted anticancer drugs (mitocans) that disrupt the energy-producing systems of cancer are emerging as new potential therapeutics. Mitochondrially targeted tamoxifen (MitoTam), an inhibitor of mitochondrial respiration respiratory c
Externí odkaz:
https://doaj.org/article/269f239884f64e4ea206c5d48ff311b3
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Externí odkaz:
https://doaj.org/article/fdd04ecb021347da955dff1822a5cc59