Type of calcineurin inhibitor and long-term outcomes following liver transplantation in patients with primary biliary cholangitis – an ELTR study

Autor: Maria C. van Hooff, Rozanne C. de Veer, Vincent Karam, Rene Adam, Pavel Taimr, Wojciech G. Polak, Hasina Pashtoun, Sarwa Darwish Murad, Christophe Corpechot, Darius Mirza, Michael Heneghan, Peter Lodge, Gabriel C. Oniscu, Douglas Thorburn, Michael Allison, Herold J. Metselaar, Caroline M. den Hoed, Adriaan J. van der Meer, Gabriel Oniscu, Johann Pratschke, Derek Manas, William Bennet, Pal-Dag Line, Emir Hot, Krzysztof Zieniewicz, Bo Goran Ericzon, Jiri Fronek, Jurgen L. Klempnauer, Allan Rasmussen, Renato Romagnoli, Petr Nemec, Arno Nordin, Andreas Paul, Paolo De Simone, R.J. Porte, Gabriela Berlakovich, Daniel Cherqui, Jacques Pirenne, Etienne Sokal, Giorgio Rossi, Daniel Candinas, Philippe Bachellier, Oleg Rummo, Karim Boudjema, Anna Mrzljak, Olivier Soubrane, Herold Metselaar, Stefan Schneeberger, Francis Navarro, Thierry Berney, Christophe Duvoux, Michele Colledan, Luciano De Carlis, Olivier Boillot, Jean Hardwigsen, Francois Rene Pruvot, Bertrand Suc, Marco Vivarelli, Pierre Alain Clavien, Hauke Lang, Maciej Kosieradzki, Frederik Berrevoet, Bruno Heyd, Matteo Cescon, Laurence Chiche, Eberhard Kochs, Umberto Baccarani, Olivier Detry, Michael Bartels, Massimo Rossi, Olivier Scatton, Vasileios Papanikolaou, Ian Alwayn, Peter Schemmer, N. Senninger, Christian Ducerf, Fabrizio Di Benedetto, Giuseppe Tisone, Silvio Nadalin, Zoltan Mathe, Marija Ribnikar, Utz Settmacher, Thomas Becker, Nuno Silva, Jorge Daniel, Irinel Popescu, Valerio Lucidi, Wolf O. Bechstein, Thomas Decaens, Jean Gugenheim, Salvatore Gruttadauria, Frausto Zamboni, Murat Zeytunlu, Jorg C. Kalff, Toomas Vali, Yaman Tokat, Ernst Klar, Julius Janek, Murat Kilic, Krum Katzarov, Lutz Fisher, Emmanuel Buc, Marco Castagneto, Tarkan Unek, Lubomir Spassov, Dirk Stippel, Christiane Bruns, Hans Schlitt, Ephrem Salame, Piotr Kalicinski, Koray Acarli

Publikováno v: JHEP Reports, Vol 6, Iss 8, Pp 101100- (2024)

Background & Aims: Tacrolimus has been associated with recurrence of primary biliary cholangitis (PBC) after liver transplantation (LT), which in turn may reduce survival. This study aimed to assess the association between the type of calcineurin inh

Externí odkaz: https://doaj.org/article/c0595d19bc354a8797ef79da5ed77889

Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes

Autor: Vaclav Janovec, Jan Hodek, Kamila Clarova, Tomas Hofman, Pavel Dostalik, Jiri Fronek, Jaroslav Chlupac, Laurence Chaperot, Sarah Durand, Thomas F. Baumert, Iva Pichova, Barbora Lubyova, Ivan Hirsch, Jan Weber

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

Abstract Recombinant interferon-α (IFN-α) treatment functionally cures chronic hepatitis B virus (HBV) infection in some individuals and suppresses virus replication in hepatocytes infected in vitro. We studied the antiviral effect of conditioned m

Externí odkaz: https://doaj.org/article/d66559148ab3479e9a9a72c1b20bba42

Rapid Drop in Coronary Heart Disease Mortality in Czech Male Population—What Was Actually behind It?

Autor: Rudolf Poledne, Anna Kralova, Hana Bartuskova, Karel Paukner, Sona Kauerova, Jiri Fronek, Vera Lanska, Ivana Kralova Lesna

Publikováno v: Biomedicines, Vol 10, Iss 11, p 2871 (2022)

The high mortality of coronary heart disease (CHD) among Czech men—one of the highest worldwide—began to decline in 1991 soon after the abolition of government subsidies to all foodstuffs rich in animal fat. As participants in the WHO MONICA Proj

Externí odkaz: https://doaj.org/article/d2afcdf98b7243e98637f027481df2b2

Vascular Remodeling of Clinically Used Patches and Decellularized Pericardial Matrices Recellularized with Autologous or Allogeneic Cells in a Porcine Carotid Artery Model

Autor: Jaroslav Chlupac, Roman Matejka, Miroslav Konarik, Robert Novotny, Zuzana Simunkova, Iveta Mrazova, Ondrej Fabian, Milan Zapletal, Zdenek Pulda, Jan Falk Lipensky, Jana Stepanovska, Karel Hanzalek, Antonin Broz, Tomas Novak, Alena Lodererova, Ludek Voska, Theodor Adla, Jiri Fronek, Miroslav Rozkot, Serhiy Forostyak, Peter Kneppo, Lucie Bacakova, Jan Pirk

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 6, p 3310 (2022)

Background: Cardiovascular surgery is confronted by a lack of suitable materials for patch repair. Acellular animal tissues serve as an abundant source of promising biomaterials. The aim of our study was to explore the bio-integration of decellulariz

Externí odkaz: https://doaj.org/article/4e8aac5d548142759998e34086b3a41c

NIRS-based monitoring of kidney graft perfusion.

Autor: Stepan Maly, Libor Janousek, Radoslav Bortel, Jan Sebek, Jiri Hospodka, Jiri Skapa, Jiri Fronek

Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0243154 (2020)

IntroductionAcute early vascular complications are rare, but serious complications after kidney transplantation. They often result in graft loss. For this reason, shortening the diagnostic process is crucial. Currently, it is standard procedure to mo

Externí odkaz: https://doaj.org/article/ac5e189fa2954e8bb9261c7710759392