Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jiri, Forejt"'
Autor:
Petr Simecek, Jiri Forejt, Robert W. Williams, Toshihiko Shiroishi, Toyoyuki Takada, Lu Lu, Thomas E. Johnson, Beth Bennett, Christian F. Deschepper, Marie-Pier Scott-Boyer, Fernando Pardo-Manuel de Villena, Gary A. Churchill
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 10, Pp 3427-3434 (2017)
Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ ×
Externí odkaz:
https://doaj.org/article/56ad0f6161d44b23a404ecacde21b422
Autor:
Jiri Forejt, Petr Jansa
Publikováno v:
Molecular Biology and Evolution. 40
Hybrid sterility (HS) is an early postzygotic reproductive isolation mechanism observed in all sexually reproducing species. Infertility of hybrids prevents gene flow between incipient species and leads to speciation. While Drosophila studies have fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ff3d5f0811b10ff2544e6a7fbd98eb0
https://doi.org/10.1093/molbev/msad083
https://doi.org/10.1093/molbev/msad083
Autor:
Markus Morkel, Bernhard G. Herrmann, Ralf Herwig, Bernd Timmermann, Jiri Forejt, Marta Caparros, Susanna H.M. Sluka, Heiner Kuhl, Christina Grimm, Matthias Lienhard, Alexandra L. Farrall
Supplementary Figures 1-7. Supplementary Figure 1: Assembly of the PWD genome and alignment to the C57BL/6 genome. Supplementary Figure 2: RNA-seq read assignment. Supplementary Figure 3: MeDIP-seq quality controls. Supplementary Figure 4: Histology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61528085d5e652659c890d8279f12770
https://doi.org/10.1158/0008-5472.22427491
https://doi.org/10.1158/0008-5472.22427491
Autor:
Markus Morkel, Bernhard G. Herrmann, Ralf Herwig, Bernd Timmermann, Jiri Forejt, Marta Caparros, Susanna H.M. Sluka, Heiner Kuhl, Christina Grimm, Matthias Lienhard, Alexandra L. Farrall
Genetic predisposition affects the penetrance of tumor-initiating mutations, such as APC mutations that stabilize β-catenin and cause intestinal tumors in mice and humans. However, the mechanisms involved in genetically predisposed penetrance are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f56271d096652a52d95a056ae79358
https://doi.org/10.1158/0008-5472.c.6512695.v1
https://doi.org/10.1158/0008-5472.c.6512695.v1
Autor:
Markus Morkel, Bernhard G. Herrmann, Ralf Herwig, Bernd Timmermann, Jiri Forejt, Marta Caparros, Susanna H.M. Sluka, Heiner Kuhl, Christina Grimm, Matthias Lienhard, Alexandra L. Farrall
Supplementary tables 1-7. Supplementary Table 1: GSEA signatures and references (Wnt target genes are taken from the HALLMARK Signature). Supplementary Table 2: 58 differentially expressed genes on chromosome 5, B6 vs C5 APC min normal intestine. Sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207acc7babae05de5529400a93fd5ab6
https://doi.org/10.1158/0008-5472.22427485
https://doi.org/10.1158/0008-5472.22427485
Autor:
Khawla FN AbuAlia, Elena Damm, Kristian K Ullrich, Amisa Mukaj, Emil Parvanov, Jiri Forejt, Linda Odenthal-Hesse
PRDM9-mediated reproductive isolation was first described in offspring ofMus musculus musculusstrain PWD/Ph andMus musculus domesticusstrain C57BL/6J. Male F1-hybrids do not complete chromosome synapsis and arrest meiosis at Prophase I. Currently, al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a55d12f75e2c9665a4a65b6f43923fc3
https://doi.org/10.1101/2023.01.17.524418
https://doi.org/10.1101/2023.01.17.524418
Publikováno v:
eLife, Vol 7 (2018)
PR domain containing 9 (Prdm9) is specifying hotspots of meiotic recombination but in hybrids between two mouse subspecies Prdm9 controls failure of meiotic chromosome synapsis and hybrid male sterility. We have previously reported that Prdm9-control
Externí odkaz:
https://doaj.org/article/b1c6bf96fb4747848e32560c73f5dc99
Autor:
Sona Gregorova, Vaclav Gergelits, Irena Chvatalova, Tanmoy Bhattacharyya, Barbora Valiskova, Vladana Fotopulosova, Petr Jansa, Diana Wiatrowska, Jiri Forejt
Publikováno v:
eLife, Vol 7 (2018)
Hybrid sterility is one of the reproductive isolation mechanisms leading to speciation. Prdm9, the only known vertebrate hybrid-sterility gene, causes failure of meiotic chromosome synapsis and infertility in male hybrids that are the offspring of tw
Externí odkaz:
https://doaj.org/article/64effb2f4fca487c99934d23ad635313
Autor:
Bernhard G. Herrmann, Bernd Timmermann, Susanna H. M. Sluka, Jiri Forejt, Ralf Herwig, Heiner Kuhl, Marta Caparros, Matthias Lienhard, Markus Morkel, Christina Grimm, Alexandra L. Farrall
Publikováno v:
Cancer research : an official organ of the American Association for Cancer Research
Genetic predisposition affects the penetrance of tumor-initiating mutations, such as APC mutations that stabilize β-catenin and cause intestinal tumors in mice and humans. However, the mechanisms involved in genetically predisposed penetrance are no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef41112547d481f0d3a206ff447172a
https://doi.org/10.1158/0008-5472.can-20-1480
https://doi.org/10.1158/0008-5472.can-20-1480
Autor:
Maria Balcova, Barbora Faltusova, Vaclav Gergelits, Tanmoy Bhattacharyya, Ondrej Mihola, Zdenek Trachtulec, Corinna Knopf, Vladana Fotopulosova, Irena Chvatalova, Sona Gregorova, Jiri Forejt
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005906 (2016)
Meiotic recombination safeguards proper segregation of homologous chromosomes into gametes, affects genetic variation within species, and contributes to meiotic chromosome recognition, pairing and synapsis. The Prdm9 gene has a dual role, it controls
Externí odkaz:
https://doaj.org/article/a71f05be23e34a5abf3ec431383f05a6