Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jir̆í Pacherník"'
Autor:
Canan Celiker, Stefan Zelenak, Samuel Lietava, Jiri Pachernik, Marketa Bebarova, Jana Zidkova, Tomas Novotny, Tomas Barta
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103541- (2024)
Human induced pluripotent stem cell (iPSC) lines were generated from peripheral blood mononuclear cells (PBMCs) isolated from two related patients diagnosed with either idiopathic ventricular fibrillation or catecholaminergic polymorphic ventricular
Externí odkaz:
https://doaj.org/article/77ac4ee2b2ac4b0a95245b0f8e25dc88
Autor:
Stjepan Uldrijan, Zbynek Zdrahal, David Potesil, Kristyna Hrazdilova, Dominika Hrossova, Dmytro Ustianenko, Katerina Chalupnikova, Jir̆í Pacherník, Katerina Cetkovska, Stepanka Vanacova
Publikováno v:
RNA
The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essenti
Publikováno v:
Neuro endocrinology letters. 29(5)
Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus regulate cell physiology including proliferation and differentiation. However, the role of ROS in neuronal differentiation of
Publikováno v:
Reproduction, nutrition, development. 42(4)
To drive neural differentiation of mouse embryonic stem (ES) cells, various culture protocols have been previously developed that all require the formation of embryoid bodies, usually combined with a treatment by all-trans retinoic acid (aRA). Here,
Autor:
Helena, Preclíková, Vítezslav, Bryja, Jirí, Pacherník, Pavel, Krejcí, Petr, Dvorák, Ales, Hampl
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 13(9)
Changes to cell cycle-regulating machinery that occur during differentiation of cells are thought to be responsible mostly for withdrawal from cycling. Here, embryonal carcinoma (EC) cell lines were found that differ in their basal levels of p27 inhi
Autor:
Klára Hilscherová, John P. Giesy, Matti Verta, Jaroslav Janošek, Tereza Šídlová, Ludĕk Bláha, Hannu Kiviranta, Jiri Novak, Martin Beníšek, Jir̆í Pacherník
Publikováno v:
Environmental Toxicology and Chemistry. 26:1591
Retinoids are known to regulate important processes such as differentiation, development, and embryogenesis. Some effects, such as malformations in frogs or changes in metabolism of birds, could be related to disruption of the retinoid signaling path
Autor:
Josef Večeřa, Jiřina Procházková, Veronika Šumberová, Veronika Pánská, Hana Paculová, Martina Kohutková Lánová, Jan Mašek, Dáša Bohačiaková, Emma Rachel Andersson, Jiří Pacherník
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Embryonic neural stem cells (NSCs), comprising neuroepithelial and radial glial cells, are indispensable precursors of neurons and glia in the mammalian developing brain. Since the process of neurogenesis occurs in a hypoxic environment, the question
Externí odkaz:
https://doaj.org/article/03ba4a2983a04dd9ab7c2dc8a299f4a1
Autor:
Eva Šafaříková, Jiří Ehlich, Stanislav Stříteský, Martin Vala, Martin Weiter, Jiří Pacherník, Lukáš Kubala, Jan Víteček
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1107 (2022)
Organic semiconductors are constantly gaining interest in regenerative medicine. Their tunable physico-chemical properties, including electrical conductivity, are very promising for the control of stem-cell differentiation. However, their use for com
Externí odkaz:
https://doaj.org/article/e8ac52504a0141fda03c76db8ec2fa6c
Autor:
Kateřina Skopalová, Katarzyna Anna Radaszkiewicz, Markéta Kadlečková, Jiří Pacherník, Antonín Minařík, Zdenka Capáková, Věra Kašpárková, Aleš Mráček, Eliška Daďová, Petr Humpolíček
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11943 (2021)
An innovative multi-step phase separation process was used to prepare tissue culture for the polystyrene-based, hierarchically structured substrates, which mimicked in vivo microenvironment and architecture. Macro- (pore area from 3000 to 18,000 µm2
Externí odkaz:
https://doaj.org/article/63c113fdf8c44fd3898603fa17024988
Autor:
Kateřina Štefková, Markéta Hanáčková, Jan Kučera, Katarzyna Anna Radaszkiewicz, Barbora Ambrůžová, Lukáš Kubala, Jiří Pacherník
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The activation of p38alpha kinase mediates cell response to various extracellular factors including many interleukins and growth factors important for haematopoiesis. The role of p38alpha kinase was previously analysed in particular haematopoietic ce
Externí odkaz:
https://doaj.org/article/f2497d2e3dd24380b85a2b536015e7f2