Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jir̆í Pacherník"'
Autor:
Canan Celiker, Stefan Zelenak, Samuel Lietava, Jiri Pachernik, Marketa Bebarova, Jana Zidkova, Tomas Novotny, Tomas Barta
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103541- (2024)
Human induced pluripotent stem cell (iPSC) lines were generated from peripheral blood mononuclear cells (PBMCs) isolated from two related patients diagnosed with either idiopathic ventricular fibrillation or catecholaminergic polymorphic ventricular
Externí odkaz:
https://doaj.org/article/77ac4ee2b2ac4b0a95245b0f8e25dc88
Autor:
Stjepan Uldrijan, Zbynek Zdrahal, David Potesil, Kristyna Hrazdilova, Dominika Hrossova, Dmytro Ustianenko, Katerina Chalupnikova, Jir̆í Pacherník, Katerina Cetkovska, Stepanka Vanacova
Publikováno v:
RNA
The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e94d25b35a53734505c1f0d0ae2fdcd
https://pubmed.ncbi.nlm.nih.gov/24141620
https://pubmed.ncbi.nlm.nih.gov/24141620
Publikováno v:
Neuro endocrinology letters. 29(5)
Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus regulate cell physiology including proliferation and differentiation. However, the role of ROS in neuronal differentiation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0cc63ee09afb7e709c8c2b3035e3a94
https://pubmed.ncbi.nlm.nih.gov/18987612
https://pubmed.ncbi.nlm.nih.gov/18987612
Publikováno v:
Reproduction, nutrition, development. 42(4)
To drive neural differentiation of mouse embryonic stem (ES) cells, various culture protocols have been previously developed that all require the formation of embryoid bodies, usually combined with a treatment by all-trans retinoic acid (aRA). Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87c730c9ace4ab887de1821a444360b7
https://pubmed.ncbi.nlm.nih.gov/12510873
https://pubmed.ncbi.nlm.nih.gov/12510873
Autor:
Helena, Preclíková, Vítezslav, Bryja, Jirí, Pacherník, Pavel, Krejcí, Petr, Dvorák, Ales, Hampl
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 13(9)
Changes to cell cycle-regulating machinery that occur during differentiation of cells are thought to be responsible mostly for withdrawal from cycling. Here, embryonal carcinoma (EC) cell lines were found that differ in their basal levels of p27 inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfcf611a57b55f728855c7d2d0d70001
https://pubmed.ncbi.nlm.nih.gov/12354751
https://pubmed.ncbi.nlm.nih.gov/12354751
Autor:
Klára Hilscherová, John P. Giesy, Matti Verta, Jaroslav Janošek, Tereza Šídlová, Ludĕk Bláha, Hannu Kiviranta, Jiri Novak, Martin Beníšek, Jir̆í Pacherník
Publikováno v:
Environmental Toxicology and Chemistry. 26:1591
Retinoids are known to regulate important processes such as differentiation, development, and embryogenesis. Some effects, such as malformations in frogs or changes in metabolism of birds, could be related to disruption of the retinoid signaling path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4345e02b80e5946e981a6a3bd04aac28
https://doi.org/10.1897/06-513r.1
https://doi.org/10.1897/06-513r.1
Autor:
Josef Večeřa, Jiřina Procházková, Veronika Šumberová, Veronika Pánská, Hana Paculová, Martina Kohutková Lánová, Jan Mašek, Dáša Bohačiaková, Emma Rachel Andersson, Jiří Pacherník
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Embryonic neural stem cells (NSCs), comprising neuroepithelial and radial glial cells, are indispensable precursors of neurons and glia in the mammalian developing brain. Since the process of neurogenesis occurs in a hypoxic environment, the question
Externí odkaz:
https://doaj.org/article/03ba4a2983a04dd9ab7c2dc8a299f4a1
Autor:
Kateřina Štefková, Markéta Hanáčková, Jan Kučera, Katarzyna Anna Radaszkiewicz, Barbora Ambrůžová, Lukáš Kubala, Jiří Pacherník
Publikováno v:
Stem Cells International, Vol 2019 (2019)
The activation of p38alpha kinase mediates cell response to various extracellular factors including many interleukins and growth factors important for haematopoiesis. The role of p38alpha kinase was previously analysed in particular haematopoietic ce
Externí odkaz:
https://doaj.org/article/f2497d2e3dd24380b85a2b536015e7f2
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Extensive research in the field of stem cells and developmental biology has revealed evidence of the role of hypoxia as an important factor regulating self-renewal and differentiation. However, comprehensive information about the exact hypoxia-mediat
Externí odkaz:
https://doaj.org/article/c54437dd1483473cafa204c9866f700f
Autor:
Katarzyna Anna Radaszkiewicz, Dominika Sýkorová, Lucia Binó, Jana Kudová, Markéta Bébarová, Jiřina Procházková, Hana Kotasová, Lukáš Kubala, Jiří Pacherník
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173140 (2017)
The differentiation of pluripotent embryonic stem (ES) cells into various lineages in vitro represents an important tool for studying the mechanisms underlying mammalian embryogenesis. It is a key technique in studies evaluating the molecular mechani
Externí odkaz:
https://doaj.org/article/4c24f865053945c683e5f4b9f4f65f94