Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jirí, Pacherník"'
Autor:
Stjepan Uldrijan, Zbynek Zdrahal, David Potesil, Kristyna Hrazdilova, Dominika Hrossova, Dmytro Ustianenko, Katerina Chalupnikova, Jir̆í Pacherník, Katerina Cetkovska, Stepanka Vanacova
Publikováno v:
RNA
The mechanisms of gene expression regulation by miRNAs have been extensively studied. However, the regulation of miRNA function and decay has long remained enigmatic. Only recently, 3′ uridylation via LIN28A-TUT4/7 has been recognized as an essenti
Publikováno v:
Neuro endocrinology letters. 29(5)
Intracellularly generated reactive oxygen species (ROS) are thought to modulate redox sensitive signaling pathways and thus regulate cell physiology including proliferation and differentiation. However, the role of ROS in neuronal differentiation of
Publikováno v:
Reproduction, nutrition, development. 42(4)
To drive neural differentiation of mouse embryonic stem (ES) cells, various culture protocols have been previously developed that all require the formation of embryoid bodies, usually combined with a treatment by all-trans retinoic acid (aRA). Here,
Autor:
Helena, Preclíková, Vítezslav, Bryja, Jirí, Pacherník, Pavel, Krejcí, Petr, Dvorák, Ales, Hampl
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 13(9)
Changes to cell cycle-regulating machinery that occur during differentiation of cells are thought to be responsible mostly for withdrawal from cycling. Here, embryonal carcinoma (EC) cell lines were found that differ in their basal levels of p27 inhi
Autor:
Klára Hilscherová, John P. Giesy, Matti Verta, Jaroslav Janošek, Tereza Šídlová, Ludĕk Bláha, Hannu Kiviranta, Jiri Novak, Martin Beníšek, Jir̆í Pacherník
Publikováno v:
Environmental Toxicology and Chemistry. 26:1591
Retinoids are known to regulate important processes such as differentiation, development, and embryogenesis. Some effects, such as malformations in frogs or changes in metabolism of birds, could be related to disruption of the retinoid signaling path